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Items: 20

1.

A Universal Vaccine against Leptospirosis: Are We Going in the Right Direction?

Grassmann AA, Souza JD, McBride AJ.

Front Immunol. 2017 Mar 9;8:256. doi: 10.3389/fimmu.2017.00256. eCollection 2017.

2.

LigB subunit vaccine confers sterile immunity against challenge in the hamster model of leptospirosis.

Conrad NL, Cruz McBride FW, Souza JD, Silveira MM, Félix S, Mendonça KS, Santos CS, Athanazio DA, Medeiros MA, Reis MG, Dellagostin OA, McBride AJ.

PLoS Negl Trop Dis. 2017 Mar 16;11(3):e0005441. doi: 10.1371/journal.pntd.0005441. eCollection 2017 Mar.

3.

Leptospira Immunoglobulin-Like Protein B (LigB) Binds to Both the C-Terminal 23 Amino Acids of Fibrinogen αC Domain and Factor XIII: Insight into the Mechanism of LigB-Mediated Blockage of Fibrinogen α Chain Cross-Linking.

Hsieh CL, Chang E, Tseng A, Ptak C, Wu LC, Su CL, McDonough SP, Lin YP, Chang YF.

PLoS Negl Trop Dis. 2016 Sep 13;10(9):e0004974. doi: 10.1371/journal.pntd.0004974. eCollection 2016 Sep.

4.

What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira.

Fouts DE, Matthias MA, Adhikarla H, Adler B, Amorim-Santos L, Berg DE, Bulach D, Buschiazzo A, Chang YF, Galloway RL, Haake DA, Haft DH, Hartskeerl R, Ko AI, Levett PN, Matsunaga J, Mechaly AE, Monk JM, Nascimento AL, Nelson KE, Palsson B, Peacock SJ, Picardeau M, Ricaldi JN, Thaipandungpanit J, Wunder EA Jr, Yang XF, Zhang JJ, Vinetz JM.

PLoS Negl Trop Dis. 2016 Feb 18;10(2):e0004403. doi: 10.1371/journal.pntd.0004403. eCollection 2016 Feb.

5.
6.

Evaluation of cell binding activities of Leptospira ECM adhesins.

Robbins GT, Hahn BL, Evangelista KV, Padmore L, Aranda PS, Coburn J.

PLoS Negl Trop Dis. 2015 Apr 14;9(4):e0003712. doi: 10.1371/journal.pntd.0003712. eCollection 2015 Apr.

7.

Thermal control of virulence factors in bacteria: a hot topic.

Lam O, Wheeler J, Tang CM.

Virulence. 2014;5(8):852-62. doi: 10.4161/21505594.2014.970949. Review.

8.

The leptospiral outer membrane.

Haake DA, Zückert WR.

Curr Top Microbiol Immunol. 2015;387:187-221. doi: 10.1007/978-3-662-45059-8_8. Review.

9.

NMR solution structure of the terminal immunoglobulin-like domain from the leptospira host-interacting outer membrane protein, LigB.

Ptak CP, Hsieh CL, Lin YP, Maltsev AS, Raman R, Sharma Y, Oswald RE, Chang YF.

Biochemistry. 2014 Aug 19;53(32):5249-60. doi: 10.1021/bi500669u. Epub 2014 Aug 4.

10.

A model system for studying the transcriptomic and physiological changes associated with mammalian host-adaptation by Leptospira interrogans serovar Copenhageni.

Caimano MJ, Sivasankaran SK, Allard A, Hurley D, Hokamp K, Grassmann AA, Hinton JC, Nally JE.

PLoS Pathog. 2014 Mar 13;10(3):e1004004. doi: 10.1371/journal.ppat.1004004. eCollection 2014 Mar.

11.

Role for cis-acting RNA sequences in the temperature-dependent expression of the multiadhesive lig proteins in Leptospira interrogans.

Matsunaga J, Schlax PJ, Haake DA.

J Bacteriol. 2013 Nov;195(22):5092-101. doi: 10.1128/JB.00663-13. Epub 2013 Sep 6.

12.

Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro.

Oliveira R, Domingos RF, Siqueira GH, Fernandes LG, Souza NM, Vieira ML, de Morais ZM, Vasconcellos SA, Nascimento AL.

PLoS Negl Trop Dis. 2013 Aug 29;7(8):e2396. doi: 10.1371/journal.pntd.0002396. eCollection 2013.

13.

Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis.

Kumar S, Puniya BL, Parween S, Nahar P, Ramachandran S.

PLoS One. 2013 Jul 29;8(7):e69790. doi: 10.1371/journal.pone.0069790. Print 2013.

14.

Accuracy of a dual path platform (DPP) assay for the rapid point-of-care diagnosis of human leptospirosis.

Nabity SA, Ribeiro GS, Aquino CL, Takahashi D, Damião AO, Gonçalves AH, Miranda-Filho DB, Greenwald R, Esfandiari J, Lyashchenko KP, Reis MG, Medeiros MA, Ko AI.

PLoS Negl Trop Dis. 2012;6(11):e1878. doi: 10.1371/journal.pntd.0001878. Epub 2012 Nov 1.

15.

Leptospira and inflammation.

Gonçalves-de-Albuquerque CF, Burth P, Silva AR, Younes-Ibrahim M, Castro-Faria-Neto HC, Castro-Faria MV.

Mediators Inflamm. 2012;2012:317950. doi: 10.1155/2012/317950. Epub 2012 Oct 21.

16.

Leptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins.

Pinne M, Matsunaga J, Haake DA.

J Bacteriol. 2012 Nov;194(22):6074-87. doi: 10.1128/JB.01119-12. Epub 2012 Sep 7.

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18.

Positive regulation of Leptospira interrogans kdp expression by KdpE as Demonstrated with a novel β-galactosidase reporter in Leptospira biflexa.

Matsunaga J, Coutinho ML.

Appl Environ Microbiol. 2012 Aug;78(16):5699-707. doi: 10.1128/AEM.00713-12. Epub 2012 Jun 8.

19.

A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans.

Coutinho ML, Choy HA, Kelley MM, Matsunaga J, Babbitt JT, Lewis MS, Aleixo JA, Haake DA.

PLoS Negl Trop Dis. 2011 Dec;5(12):e1422. doi: 10.1371/journal.pntd.0001422. Epub 2011 Dec 13.

20.

Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin.

Figueira CP, Croda J, Choy HA, Haake DA, Reis MG, Ko AI, Picardeau M.

BMC Microbiol. 2011 Jun 9;11:129. doi: 10.1186/1471-2180-11-129.

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