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Tuberculosis Biomarkers: From Diagnosis to Protection.

Goletti D, Petruccioli E, Joosten SA, Ottenhoff TH.

Infect Dis Rep. 2016 Jun 24;8(2):6568. doi: 10.4081/idr.2016.6568. eCollection 2016 Jun 24. Review.


The mc2-CMX vaccine induces an enhanced immune response against Mycobacterium tuberculosis compared to Bacillus Calmette-Guérin but with similar lung inflammatory effects.

Oliveira FM, Trentini MM, Junqueira-Kipnis AP, Kipnis A.

Mem Inst Oswaldo Cruz. 2016 Apr;111(4):223-31. doi: 10.1590/0074-02760150411.


The Secreted Protein Rv1860 of Mycobacterium tuberculosis Stimulates Human Polyfunctional CD8+ T Cells.

Satchidanandam V, Kumar N, Biswas S, Jumani RS, Jain C, Rani R, Aggarwal B, Singh J, Kotnur MR, Sridharan A.

Clin Vaccine Immunol. 2016 Apr 4;23(4):282-93. doi: 10.1128/CVI.00554-15. Print 2016 Apr.


Tissue Distribution of Memory T and B Cells in Rhesus Monkeys following Influenza A Infection.

Pichyangkul S, Yongvanitchit K, Limsalakpetch A, Kum-Arb U, Im-Erbsin R, Boonnak K, Thitithayanont A, Jongkaewwattana A, Wiboon-ut S, Mongkolsirichaikul D, Mahanonda R, Spring M, Chuang I, Mason CJ, Saunders DL.

J Immunol. 2015 Nov 1;195(9):4378-86. doi: 10.4049/jimmunol.1501702. Epub 2015 Sep 25.


Correlates of Vaccine-Induced Protection against Mycobacterium tuberculosis Revealed in Comparative Analyses of Lymphocyte Populations.

Kurtz SL, Elkins KL.

Clin Vaccine Immunol. 2015 Oct;22(10):1096-108. doi: 10.1128/CVI.00301-15. Epub 2015 Aug 12.


Alarmin IL-33 elicits potent TB-specific cell-mediated responses.

Villarreal DO, Siefert RJ, Weiner DB.

Hum Vaccin Immunother. 2015;11(8):1954-60. doi: 10.1080/21645515.2015.1026499.


Effects of the fusion design and immunization route on the immunogenicity of Ag85A-Mtb32 in adenoviral vectored tuberculosis vaccine.

Zhang Y, Feng L, Li L, Wang D, Li C, Sun C, Li P, Zheng X, Liu Y, Yang W, Niu X, Zhong N, Chen L.

Hum Vaccin Immunother. 2015;11(7):1803-13. doi: 10.1080/21645515.2015.1042193.


COMPASS identifies T-cell subsets correlated with clinical outcomes.

Lin L, Finak G, Ushey K, Seshadri C, Hawn TR, Frahm N, Scriba TJ, Mahomed H, Hanekom W, Bart PA, Pantaleo G, Tomaras GD, Rerks-Ngarm S, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Michael NL, Kim JH, Robb ML, O'Connell RJ, Karasavvas N, Gilbert P, C De Rosa S, McElrath MJ, Gottardo R.

Nat Biotechnol. 2015 Jun;33(6):610-6. doi: 10.1038/nbt.3187. Epub 2015 May 25.


Quest for correlates of protection against tuberculosis.

Bhatt K, Verma S, Ellner JJ, Salgame P.

Clin Vaccine Immunol. 2015 Mar;22(3):258-66. doi: 10.1128/CVI.00721-14. Epub 2015 Jan 14. Review.


T cell receptor binding affinity governs the functional profile of cancer-specific CD8+ T cells.

Tan MP, Gerry AB, Brewer JE, Melchiori L, Bridgeman JS, Bennett AD, Pumphrey NJ, Jakobsen BK, Price DA, Ladell K, Sewell AK.

Clin Exp Immunol. 2015 May;180(2):255-70. doi: 10.1111/cei.12570.


Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG.

Villarreal DO, Walters J, Laddy DJ, Yan J, Weiner DB.

Hum Vaccin Immunother. 2014;10(8):2188-98. doi: 10.4161/hv.29574.


A subset of circulating blood mycobacteria-specific CD4 T cells can predict the time to Mycobacterium tuberculosis sputum culture conversion.

Riou C, Gray CM, Lugongolo M, Gwala T, Kiravu A, Deniso P, Stewart-Isherwood L, Omar SV, Grobusch MP, Coetzee G, Conradie F, Ismail N, Kaplan G, Fallows D.

PLoS One. 2014 Jul 21;9(7):e102178. doi: 10.1371/journal.pone.0102178. eCollection 2014.


DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor B elicits polyfunctional CD8(+) T cell responses.

Lee J, Kim J, Lee J, Shin SJ, Shin EC.

Clin Exp Vaccine Res. 2014 Jul;3(2):235-43. doi: 10.7774/cevr.2014.3.2.235. Epub 2014 Jun 20.


Defining features of protective CD4 T cell responses to Mycobacterium tuberculosis.

Sakai S, Mayer-Barber KD, Barber DL.

Curr Opin Immunol. 2014 Aug;29:137-42. doi: 10.1016/j.coi.2014.06.003. Review.


Central memory CD4+ T cells are responsible for the recombinant Bacillus Calmette-Guérin ΔureC::hly vaccine's superior protection against tuberculosis.

Vogelzang A, Perdomo C, Zedler U, Kuhlmann S, Hurwitz R, Gengenbacher M, Kaufmann SH.

J Infect Dis. 2014 Dec 15;210(12):1928-37. doi: 10.1093/infdis/jiu347. Epub 2014 Jun 18.


Novel vaccination strategies against tuberculosis.

Andersen P, Kaufmann SH.

Cold Spring Harb Perspect Med. 2014 Jun 2;4(6). pii: a018523. doi: 10.1101/cshperspect.a018523. Review.


Functional Signatures of Human CD4 and CD8 T Cell Responses to Mycobacterium tuberculosis.

Prezzemolo T, Guggino G, La Manna MP, Di Liberto D, Dieli F, Caccamo N.

Front Immunol. 2014 Apr 22;5:180. doi: 10.3389/fimmu.2014.00180. eCollection 2014. Review.

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