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Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy.

Medrano RFV, Hunger A, Mendonça SA, Barbuto JAM, Strauss BE.

Oncotarget. 2017 Jul 25;8(41):71249-71284. doi: 10.18632/oncotarget.19531. eCollection 2017 Sep 19. Review.


Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania.

Amelio P, Portevin D, Reither K, Mhimbira F, Mpina M, Tumbo A, Nickel B, Marti H, Knopp S, Ding S, Penn-Nicholson A, Darboe F, Ohmiti K, Scriba TJ, Pantaleo G, Daubenberger C, Perreau M.

PLoS Negl Trop Dis. 2017 Jul 31;11(7):e0005817. doi: 10.1371/journal.pntd.0005817. eCollection 2017 Jul.


Targeting Pattern Recognition Receptors (PRR) for Vaccine Adjuvantation: From Synthetic PRR Agonists to the Potential of Defective Interfering Particles of Viruses.

Vasou A, Sultanoglu N, Goodbourn S, Randall RE, Kostrikis LG.

Viruses. 2017 Jul 13;9(7). pii: E186. doi: 10.3390/v9070186. Review.


Peg-Interferon Lambda Treatment Induces Robust Innate and Adaptive Immunity in Chronic Hepatitis B Patients.

Phillips S, Mistry S, Riva A, Cooksley H, Hadzhiolova-Lebeau T, Plavova S, Katzarov K, Simonova M, Zeuzem S, Woffendin C, Chen PJ, Peng CY, Chang TT, Lueth S, De Knegt R, Choi MS, Wedemeyer H, Dao M, Kim CW, Chu HC, Wind-Rotolo M, Williams R, Cooney E, Chokshi S.

Front Immunol. 2017 May 29;8:621. doi: 10.3389/fimmu.2017.00621. eCollection 2017.


Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus.

Uebele J, Stein C, Nguyen MT, Schneider A, Kleinert F, Tichá O, Bierbaum G, Götz F, Bekeredjian-Ding I.

PLoS Pathog. 2017 May 25;13(5):e1006387. doi: 10.1371/journal.ppat.1006387. eCollection 2017 May.


CpG oligodeoxynucleotide nanomedicines for the prophylaxis or treatment of cancers, infectious diseases, and allergies.

Hanagata N.

Int J Nanomedicine. 2017 Jan 16;12:515-531. doi: 10.2147/IJN.S114477. eCollection 2017. Review.


Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine.

Raeven RH, Brummelman J, Pennings JL, van der Maas L, Tilstra W, Helm K, van Riet E, Jiskoot W, van Els CA, Han WG, Kersten GF, Metz B.

Sci Rep. 2016 Dec 1;6:38240. doi: 10.1038/srep38240.


Pretreatment of activated human CD8 T cells with IL-12 leads to enhanced TCR-induced signaling and cytokine production.

Vacaflores A, Freedman SN, Chapman NM, Houtman JC.

Mol Immunol. 2017 Jan;81:1-15. doi: 10.1016/j.molimm.2016.11.008. Epub 2016 Nov 22.


Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2V617F allelic burden.

Kovacsovics-Bankowski M, Kelley TW, Efimova O, Kim SJ, Wilson A, Swierczek S, Prchal J.

Exp Hematol Oncol. 2016 Sep 27;5:28. eCollection 2015.


Increased attenuation but decreased immunogenicity by deletion of multiple vaccinia virus immunomodulators.

Sumner RP, Ren H, Ferguson BJ, Smith GL.

Vaccine. 2016 Sep 14;34(40):4827-34. doi: 10.1016/j.vaccine.2016.08.002. Epub 2016 Aug 17.


Deletion of A44L, A46R and C12L Vaccinia Virus Genes from the MVA Genome Improved the Vector Immunogenicity by Modifying the Innate Immune Response Generating Enhanced and Optimized Specific T-Cell Responses.

Holgado MP, Falivene J, Maeto C, Amigo M, Pascutti MF, Vecchione MB, Bruttomesso A, Calamante G, Del Médico-Zajac MP, Gherardi MM.

Viruses. 2016 May 23;8(5). pii: E139. doi: 10.3390/v8050139.


Sensitivity of African swine fever virus to type I interferon is linked to genes within multigene families 360 and 505.

Golding JP, Goatley L, Goodbourn S, Dixon LK, Taylor G, Netherton CL.

Virology. 2016 Jun;493:154-61. doi: 10.1016/j.virol.2016.03.019. Epub 2016 Apr 1.


STAT4-mediated transcriptional repression of the IL5 gene in human memory Th2 cells.

Gonzales-van Horn SR, Estrada LD, van Oers NS, Farrar JD.

Eur J Immunol. 2016 Jun;46(6):1504-10. doi: 10.1002/eji.201546050. Epub 2016 Apr 8.


Type I Interferons Regulate the Magnitude and Functionality of Mouse Polyomavirus-Specific CD8 T Cells in a Virus Strain-Dependent Manner.

Qin Q, Shwetank, Frost EL, Maru S, Lukacher AE.

J Virol. 2016 Apr 29;90(10):5187-99. doi: 10.1128/JVI.00199-16. Print 2016 May 15.


In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens.

Alyaqoub FS, Aldhamen YA, Koestler BJ, Bruger EL, Seregin SS, Pereira-Hicks C, Godbehere S, Waters CM, Amalfitano A.

J Immunol. 2016 Feb 15;196(4):1741-52. doi: 10.4049/jimmunol.1501272. Epub 2016 Jan 20.


Analysis of Th17 and Tc17 Frequencies and Antiviral Defenses in Gut-Associated Lymphoid Tissue of Chronic HIV-1 Positive Patients.

d'Ettorre G, Ceccarelli G, Andreotti M, Selvaggi C, Giustini N, Serafino S, Schietroma I, Nunnari G, Antonelli G, Vullo V, Scagnolari C.

Mediators Inflamm. 2015;2015:395484. doi: 10.1155/2015/395484. Epub 2015 Jun 28.


Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation.

Borrego B, Rodríguez-Pulido M, Revilla C, Álvarez B, Sobrino F, Domínguez J, Sáiz M.

Viruses. 2015 Jul 17;7(7):3954-73. doi: 10.3390/v7072807.


Interferon at the crossroads of allergy and viral infections.

Gonzales-van Horn SR, Farrar JD.

J Leukoc Biol. 2015 Aug;98(2):185-94. doi: 10.1189/jlb.3RU0315-099R. Epub 2015 May 29. Review.


Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes.

Lieskovská J, Páleníková J, Langhansová H, Campos Chagas A, Calvo E, Kotsyfakis M, Kopecký J.

Parasit Vectors. 2015 May 15;8:275. doi: 10.1186/s13071-015-0887-1.

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