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Recent insights into the molecular pathogenesis of Crohn's disease: a review of emerging therapeutic targets.

Manuc TE, Manuc MM, Diculescu MM.

Clin Exp Gastroenterol. 2016 Mar 15;9:59-70. doi: 10.2147/CEG.S53381. Review.


Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection.

Bretin A, Carrière J, Dalmasso G, Bergougnoux A, B'chir W, Maurin AC, Müller S, Seibold F, Barnich N, Bruhat A, Darfeuille-Michaud A, Nguyen HT.

Autophagy. 2016 May 3;12(5):770-83. doi: 10.1080/15548627.2016.1156823.


Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population.

Park HJ, Jung ES, Kong KA, Park EM, Cheon JH, Choi JH.

Sci Rep. 2016 Mar 11;6:22887. doi: 10.1038/srep22887.


Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.

Ro SH, Xue X, Ramakrishnan SK, Cho CS, Namkoong S, Jang I, Semple IA, Ho A, Park HW, Shah YM, Lee JH.

Elife. 2016 Feb 25;5:e12204. doi: 10.7554/eLife.12204.


Genetic association between CARD9 variants and inflammatory bowel disease was not replicated in a Chinese Han population.

Wang Z, Fan R, Wang L, Zhou J, Zheng S, Hu S, Chen M, Zhang T, Lin Y, Zhang M, Zhong J.

Int J Clin Exp Pathol. 2015 Oct 1;8(10):13465-70.


Phosphoethanolamine Modification of Neisseria gonorrhoeae Lipid A Reduces Autophagy Flux in Macrophages.

Zughaier SM, Kandler JL, Balthazar JT, Shafer WM.

PLoS One. 2015 Dec 7;10(12):e0144347. doi: 10.1371/journal.pone.0144347.


Physical Fitness in Adolescence and Subsequent Inflammatory Bowel Disease Risk.

Melinder C, Hiyoshi A, Hussein O, Halfvarson J, Ekbom A, Montgomery S.

Clin Transl Gastroenterol. 2015 Nov 5;6:e121. doi: 10.1038/ctg.2015.49.


Pathogenesis of Crohn's disease.

Boyapati R, Satsangi J, Ho GT.

F1000Prime Rep. 2015 Apr 2;7:44. doi: 10.12703/P7-44. Review.


Critical roles of intestinal epithelial vitamin D receptor signaling in controlling gut mucosal inflammation.

Li YC, Chen Y, Du J.

J Steroid Biochem Mol Biol. 2015 Apr;148:179-83. doi: 10.1016/j.jsbmb.2015.01.011. Review.


Prioritisation and network analysis of Crohn's disease susceptibility genes.

Muraro D, Lauffenburger DA, Simmons A.

PLoS One. 2014 Sep 30;9(9):e108624. doi: 10.1371/journal.pone.0108624.


Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases.

Guo B, Li Z.

Front Genet. 2014 Jul 25;5:242. doi: 10.3389/fgene.2014.00242. Review.


Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell.

Hosogi S, Kusuzaki K, Inui T, Wang X, Marunaka Y.

J Cell Mol Med. 2014 Jun;18(6):1124-33. doi: 10.1111/jcmm.12257.


ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients.

Wolfkamp SC, Verseyden C, Vogels EW, Meisner S, Boonstra K, Peters CP, Stokkers PC, te Velde AA.

World J Gastroenterol. 2014 Mar 14;20(10):2664-72. doi: 10.3748/wjg.v20.i10.2664.


Inflammasome activation has an important role in the development of spontaneous colitis.

Zhang J, Fu S, Sun S, Li Z, Guo B.

Mucosal Immunol. 2014 Sep;7(5):1139-50. doi: 10.1038/mi.2014.1.


Role of the advanced glycation end products receptor in Crohn's disease inflammation.

Ciccocioppo R, Vanoli A, Klersy C, Imbesi V, Boccaccio V, Manca R, Betti E, Cangemi GC, Strada E, Besio R, Rossi A, Falcone C, Ardizzone S, Fociani P, Danelli P, Corazza GR.

World J Gastroenterol. 2013 Dec 7;19(45):8269-81. doi: 10.3748/wjg.v19.i45.8269.


Association between variants of the autophagy related gene--IRGM and susceptibility to Crohn's disease and ulcerative colitis: a meta-analysis.

Lu XC, Tao Y, Wu C, Zhao PL, Li K, Zheng JY, Li LX.

PLoS One. 2013 Nov 13;8(11):e80602. doi: 10.1371/journal.pone.0080602.


Autophagosomes contribute to intracellular lipid distribution in enterocytes.

Khaldoun SA, Emond-Boisjoly MA, Chateau D, Carrière V, Lacasa M, Rousset M, Demignot S, Morel E.

Mol Biol Cell. 2014 Jan;25(1):118-32. doi: 10.1091/mbc.E13-06-0324.


An update on granulomatous diseases of the oral tissues.

Alawi F.

Dent Clin North Am. 2013 Oct;57(4):657-71. doi: 10.1016/j.cden.2013.07.004. Review.


Irgm1-deficient mice exhibit Paneth cell abnormalities and increased susceptibility to acute intestinal inflammation.

Liu B, Gulati AS, Cantillana V, Henry SC, Schmidt EA, Daniell X, Grossniklaus E, Schoenborn AA, Sartor RB, Taylor GA.

Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15;305(8):G573-84. doi: 10.1152/ajpgi.00071.2013.


Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis.

Liu W, Chen Y, Golan MA, Annunziata ML, Du J, Dougherty U, Kong J, Musch M, Huang Y, Pekow J, Zheng C, Bissonnette M, Hanauer SB, Li YC.

J Clin Invest. 2013 Sep;123(9):3983-96. doi: 10.1172/JCI65842.

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