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Items: 18


Clinical Advancements in the Targeted Therapies against Liver Fibrosis.

Bansal R, Nagórniewicz B, Prakash J.

Mediators Inflamm. 2016;2016:7629724. doi: 10.1155/2016/7629724. Epub 2016 Nov 24. Review.


Autophagy in Diabetic Retinopathy.

Rosa MD, Distefano G, Gagliano C, Rusciano D, Malaguarnera L.

Curr Neuropharmacol. 2016;14(8):810-825. Review.


Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice.

Hurez V, Dao V, Liu A, Pandeswara S, Gelfond J, Sun L, Bergman M, Orihuela CJ, Galvan V, Padrón Á, Drerup J, Liu Y, Hasty P, Sharp ZD, Curiel TJ.

Aging Cell. 2015 Dec;14(6):945-56. doi: 10.1111/acel.12380. Epub 2015 Aug 28.


One-Year Outcomes of the SAVE Study: Sirolimus as a Therapeutic Approach for UVEitis.

Ibrahim MA, Sepah YJ, Watters A, Bittencourt M, Vigil EM, Do DV, Nguyen QD.

Transl Vis Sci Technol. 2015 Mar 10;4(2):4. eCollection 2015 Mar.


The two faces of miR-29.

Ślusarz A, Pulakat L.

J Cardiovasc Med (Hagerstown). 2015 Jul;16(7):480-90. doi: 10.2459/JCM.0000000000000246. Review.


Regulation of cardiac expression of the diabetic marker microRNA miR-29.

Arnold N, Koppula PR, Gul R, Luck C, Pulakat L.

PLoS One. 2014 Jul 25;9(7):e103284. doi: 10.1371/journal.pone.0103284. eCollection 2014.


Postoperative complications associated with perioperative sirolimus prior to pediatric cardiac retransplantation.

Goldberg JF, Jeewa A, Dreyer WJ, Adams GJ, Cabrera AG, Price JF, Heinle JS, Denfield SW.

J Pediatr Pharmacol Ther. 2014 Jan;19(1):30-4. doi: 10.5863/1551-6776-19.1.30.


Systemic and nonrenal adverse effects occurring in renal transplant patients treated with mTOR inhibitors.

Zaza G, Tomei P, Ria P, Granata S, Boschiero L, Lupo A.

Clin Dev Immunol. 2013;2013:403280. doi: 10.1155/2013/403280. Epub 2013 Sep 19. Review.


Peripheral administration of translation inhibitors reverses increased hyperalgesia in a model of chronic pain in the rat.

Ferrari LF, Bogen O, Chu C, Levine JD.

J Pain. 2013 Jul;14(7):731-8. doi: 10.1016/j.jpain.2013.01.779. Epub 2013 May 8.


Glucosamine activates autophagy in vitro and in vivo.

Caramés B, Kiosses WB, Akasaki Y, Brinson DC, Eap W, Koziol J, Lotz MK.

Arthritis Rheum. 2013 Jul;65(7):1843-52. doi: 10.1002/art.37977.


Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE Study.

Nguyen QD, Ibrahim MA, Watters A, Bittencourt M, Yohannan J, Sepah YJ, Dunn JP, Naor J, Shams N, Shaikh O, Leder HA, Do DV.

J Ophthalmic Inflamm Infect. 2013 Feb 11;3(1):32. doi: 10.1186/1869-5760-3-32.


Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: implications for iron metabolism.

La P, Yang G, Dennery PA.

J Biol Chem. 2013 May 3;288(18):12901-9. doi: 10.1074/jbc.M112.424499. Epub 2013 Mar 18.


Cytopenia and autoimmune diseases: a vicious cycle fueled by mTOR dysregulation in hematopoietic stem cells.

Zheng P, Chang X, Lu Q, Liu Y.

J Autoimmun. 2013 Mar;41:182-7. doi: 10.1016/j.jaut.2012.12.011. Epub 2013 Feb 1. Review.


Cellular and molecular mechanisms of intestinal fibrosis.

Speca S, Giusti I, Rieder F, Latella G.

World J Gastroenterol. 2012 Jul 28;18(28):3635-61. doi: 10.3748/wjg.v18.i28.3635.


The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.

Madhunapantula SV, Mosca PJ, Robertson GP.

Cancer Biol Ther. 2011 Dec 15;12(12):1032-49. doi: 10.4161/cbt.12.12.18442. Epub 2011 Dec 15. Review.


Potential Therapeutic Roles for Inhibition of the PI3K/Akt/mTOR Pathway in the Pathophysiology of Diabetic Retinopathy.

Jacot JL, Sherris D.

J Ophthalmol. 2011;2011:589813. doi: 10.1155/2011/589813. Epub 2011 Oct 30.


Convergent pathogenic pathways in Alzheimer's and Huntington's diseases: shared targets for drug development.

Ehrnhoefer DE, Wong BK, Hayden MR.

Nat Rev Drug Discov. 2011 Oct 21;10(11):853-67. doi: 10.1038/nrd3556. Review.


Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA.

Lotz MK, Caramés B.

Nat Rev Rheumatol. 2011 Aug 2;7(10):579-87. doi: 10.1038/nrrheum.2011.109. Review.

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