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Items: 1 to 20 of 71


Mechanical stability of talin rod controls cell migration and substrate sensing.

Rahikainen R, von Essen M, Schaefer M, Qi L, Azizi L, Kelly C, Ihalainen TO, Wehrle-Haller B, Bastmeyer M, Huang C, Hytönen VP.

Sci Rep. 2017 Jun 15;7(1):3571. doi: 10.1038/s41598-017-03335-2.


Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.

Lim D, Lu Y, Rudd CE.

Immunol Lett. 2016 Apr;172:40-6. doi: 10.1016/j.imlet.2016.02.004. Epub 2016 Feb 19.


Efficient Exploration of Membrane-Associated Phenomena at Atomic Resolution.

Vermaas JV, Baylon JL, Arcario MJ, Muller MP, Wu Z, Pogorelov TV, Tajkhorshid E.

J Membr Biol. 2015 Jun;248(3):563-82. doi: 10.1007/s00232-015-9806-9. Epub 2015 May 22. Review.


Structural and mechanistic insights into the recruitment of talin by RIAM in integrin signaling.

Chang YC, Zhang H, Franco-Barraza J, Brennan ML, Patel T, Cukierman E, Wu J.

Structure. 2014 Dec 2;22(12):1810-1820. doi: 10.1016/j.str.2014.09.020. Epub 2014 Nov 20.


The role of phosphoinositide-regulated actin reorganization in chemotaxis and cell migration.

Wu CY, Lin MW, Wu DC, Huang YB, Huang HT, Chen CL.

Br J Pharmacol. 2014 Dec;171(24):5541-54. doi: 10.1111/bph.12777. Epub 2014 Nov 24. Review.


Membrane-induced structural rearrangement and identification of a novel membrane anchor in talin F2F3.

Arcario MJ, Tajkhorshid E.

Biophys J. 2014 Nov 4;107(9):2059-69. doi: 10.1016/j.bpj.2014.09.022.


A talin mutant that impairs talin-integrin binding in platelets decelerates αIIbβ3 activation without pathological bleeding.

Stefanini L, Ye F, Snider AK, Sarabakhsh K, Piatt R, Paul DS, Bergmeier W, Petrich BG.

Blood. 2014 Apr 24;123(17):2722-31. doi: 10.1182/blood-2013-12-543363. Epub 2014 Feb 28.


Mechanisms of talin-dependent integrin signaling and crosstalk.

Das M, Ithychanda S, Qin J, Plow EF.

Biochim Biophys Acta. 2014 Feb;1838(2):579-88. doi: 10.1016/j.bbamem.2013.07.017. Epub 2013 Jul 24. Review.


c-Abl Kinase Is a Regulator of αvβ3 Integrin Mediated Melanoma A375 Cell Migration.

Zhang C, Yang C, Wang R, Jiao Y, Ampah KK, Wang X, Zeng X.

PLoS One. 2013 Jun 21;8(6):e66108. doi: 10.1371/journal.pone.0066108. Print 2013.


The SNARE protein Syp71 is essential for turnip mosaic virus infection by mediating fusion of virus-induced vesicles with chloroplasts.

Wei T, Zhang C, Hou X, Sanfaçon H, Wang A.

PLoS Pathog. 2013;9(5):e1003378. doi: 10.1371/journal.ppat.1003378. Epub 2013 May 16.


Regulation and physiological roles of the calpain system in muscular disorders.

Sorimachi H, Ono Y.

Cardiovasc Res. 2012 Oct 1;96(1):11-22. doi: 10.1093/cvr/cvs157. Epub 2012 Apr 27. Review.


Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics.

Bate N, Gingras AR, Bachir A, Horwitz R, Ye F, Patel B, Goult BT, Critchley DR.

PLoS One. 2012;7(4):e34461. doi: 10.1371/journal.pone.0034461. Epub 2012 Apr 4.


Subcellular localization of talin is regulated by inter-domain interactions.

Banno A, Goult BT, Lee H, Bate N, Critchley DR, Ginsberg MH.

J Biol Chem. 2012 Apr 20;287(17):13799-812. doi: 10.1074/jbc.M112.341214. Epub 2012 Feb 18.


The final steps of integrin activation: the end game.

Shattil SJ, Kim C, Ginsberg MH.

Nat Rev Mol Cell Biol. 2010 Apr;11(4):288-300. doi: 10.1038/nrm2871. Review.


Cdk5: A regulator of epithelial cell adhesion and migration.

Tripathi BK, Zelenka PS.

Cell Adh Migr. 2010 Jul-Sep;4(3):333-6. Epub 2010 Jul 5.


Structural basis for the autoinhibition of talin in regulating integrin activation.

Goksoy E, Ma YQ, Wang X, Kong X, Perera D, Plow EF, Qin J.

Mol Cell. 2008 Jul 11;31(1):124-33. doi: 10.1016/j.molcel.2008.06.011.


Integrin activation.

Banno A, Ginsberg MH.

Biochem Soc Trans. 2008 Apr;36(Pt 2):229-34. doi: 10.1042/BST0360229. Review.


Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo.

Nieswandt B, Moser M, Pleines I, Varga-Szabo D, Monkley S, Critchley D, Fässler R.

J Exp Med. 2007 Dec 24;204(13):3113-8. Epub 2007 Dec 17.

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