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Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins.

Sathiyamoorthy K, Hu YX, Möhl BS, Chen J, Longnecker R, Jardetzky TS.

Nat Commun. 2016 Dec 8;7:13557. doi: 10.1038/ncomms13557.


Regulation of HSV glycoprotein induced cascade of events governing cell-cell fusion.

Atanasiu D, Saw WT, Eisenberg RJ, Cohen GH.

J Virol. 2016 Sep 14. pii: JVI.01501-16. [Epub ahead of print]


Structural and Mechanistic Insights into the Tropism of Epstein-Barr Virus.

Möhl BS, Chen J, Sathiyamoorthy K, Jardetzky TS, Longnecker R.

Mol Cells. 2016 Apr 30;39(4):286-91. doi: 10.14348/molcells.2016.0066. Epub 2016 Apr 6. Review.


Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein B.

Zeev-Ben-Mordehai T, Vasishtan D, Hernández Durán A, Vollmer B, White P, Prasad Pandurangan A, Siebert CA, Topf M, Grünewald K.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4176-81. doi: 10.1073/pnas.1523234113. Epub 2016 Mar 24.


Retargeting Strategies for Oncolytic Herpes Simplex Viruses.

Campadelli-Fiume G, Petrovic B, Leoni V, Gianni T, Avitabile E, Casiraghi C, Gatta V.

Viruses. 2016 Feb 26;8(3):63. doi: 10.3390/v8030063. Review.


gH/gL supercomplexes at early stages of herpesvirus entry.

Heldwein EE.

Curr Opin Virol. 2016 Jun;18:1-8. doi: 10.1016/j.coviro.2016.01.010. Epub 2016 Feb 2. Review.


Mutations in Pseudorabies Virus Glycoproteins gB, gD, and gH Functionally Compensate for the Absence of gL.

Schröter C, Vallbracht M, Altenschmidt J, Kargoll S, Fuchs W, Klupp BG, Mettenleiter TC.

J Virol. 2015 Dec 9;90(5):2264-72. doi: 10.1128/JVI.02739-15.


Comparative Mutagenesis of Pseudorabies Virus and Epstein-Barr Virus gH Identifies a Structural Determinant within Domain III of gH Required for Surface Expression and Entry Function.

Möhl BS, Schröter C, Klupp BG, Fuchs W, Mettenleiter TC, Jardetzky TS, Longnecker R.

J Virol. 2015 Dec 9;90(5):2285-93. doi: 10.1128/JVI.03032-15.


Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL.

Schultz EP, Lanchy JM, Ellerbeck EE, Ryckman BJ.

J Virol. 2015 Dec 9;90(5):2294-305. doi: 10.1128/JVI.01875-15.


Probing the interactions of CdTe quantum dots with pseudorabies virus.

Du T, Cai K, Han H, Fang L, Liang J, Xiao S.

Sci Rep. 2015 Nov 10;5:16403. doi: 10.1038/srep16403.


Functional Characterization of Glycoprotein H Chimeras Composed of Conserved Domains of the Pseudorabies Virus and Herpes Simplex Virus 1 Homologs.

Böhm SW, Backovic M, Klupp BG, Rey FA, Mettenleiter TC, Fuchs W.

J Virol. 2015 Oct 21;90(1):421-32. doi: 10.1128/JVI.01985-15.


Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry.

Gianni T, Massaro R, Campadelli-Fiume G.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3901-10. doi: 10.1073/pnas.1506846112. Epub 2015 Jul 8.


Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus Are Attributed to Epitopes on gD, gB, or Both and Can Be Type Specific.

Cairns TM, Huang ZY, Gallagher JR, Lin Y, Lou H, Whitbeck JC, Wald A, Cohen GH, Eisenberg RJ.

J Virol. 2015 Sep;89(18):9213-31. doi: 10.1128/JVI.01213-15. Epub 2015 Jun 24.


The Engineering of a Novel Ligand in gH Confers to HSV an Expanded Tropism Independent of gD Activation by Its Receptors.

Gatta V, Petrovic B, Campadelli-Fiume G.

PLoS Pathog. 2015 May 21;11(5):e1004907. doi: 10.1371/journal.ppat.1004907. eCollection 2015 May 21.


A Functional Interaction between Herpes Simplex Virus 1 Glycoprotein gH/gL Domains I and II and gD Is Defined by Using Alphaherpesvirus gH and gL Chimeras.

Fan Q, Longnecker R, Connolly SA.

J Virol. 2015 Jul;89(14):7159-69. doi: 10.1128/JVI.00740-15. Epub 2015 Apr 29.


A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL.

Xing Y, Oliver SL, Nguyen T, Ciferri C, Nandi A, Hickman J, Giovani C, Yang E, Palladino G, Grose C, Uematsu Y, Lilja AE, Arvin AM, Carfí A.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6056-61. doi: 10.1073/pnas.1501176112. Epub 2015 Apr 27.


Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes.

Ciferri C, Chandramouli S, Donnarumma D, Nikitin PA, Cianfrocco MA, Gerrein R, Feire AL, Barnett SW, Lilja AE, Rappuoli R, Norais N, Settembre EC, Carfi A.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1767-72. doi: 10.1073/pnas.1424818112. Epub 2015 Jan 26.


Structure-based functional analyses of domains II and III of pseudorabies virus glycoprotein H.

Böhm SW, Eckroth E, Backovic M, Klupp BG, Rey FA, Mettenleiter TC, Fuchs W.

J Virol. 2015 Jan 15;89(2):1364-76. doi: 10.1128/JVI.02765-14. Epub 2014 Nov 12.


Epstein-Barr virus infection mechanisms.

Chesnokova LS, Hutt-Fletcher LM.

Chin J Cancer. 2014 Nov;33(11):545-8. doi: 10.5732/cjc.014.10168. Epub 2014 Oct 17. Review.

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