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Items: 1 to 20 of 26


Toward understanding of the mechanisms of Mediator function in vivo: Focus on the preinitiation complex assembly.

Eychenne T, Werner M, Soutourina J.

Transcription. 2017;8(5):328-342. doi: 10.1080/21541264.2017.1329000. Epub 2017 Aug 25. Review.


ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain.

Currie SL, Doane JJ, Evans KS, Bhachech N, Madison BJ, Lau DKW, McIntosh LP, Skalicky JJ, Clark KA, Graves BJ.

J Mol Biol. 2017 Oct 13;429(20):2975-2995. doi: 10.1016/j.jmb.2017.06.024. Epub 2017 Jul 17.


Control of Muscle Metabolism by the Mediator Complex.

Amoasii L, Olson EN, Bassel-Duby R.

Cold Spring Harb Perspect Med. 2018 Feb 1;8(2). pii: a029843. doi: 10.1101/cshperspect.a029843. Review.


Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition.

Fan W, Lam SM, Xin J, Yang X, Liu Z, Liu Y, Wang Y, Shui G, Huang X.

PLoS Genet. 2017 Mar 8;13(3):e1006664. doi: 10.1371/journal.pgen.1006664. eCollection 2017 Mar.


Regulation of metabolism by the Mediator complex.

Youn DY, Xiaoli AM, Pessin JE, Yang F.

Biophys Rep. 2016;2(2):69-77. doi: 10.1007/s41048-016-0031-6. Epub 2016 Nov 1.


Synergistic activation of Arg1 gene by retinoic acid and IL-4 involves chromatin remodeling for transcription initiation and elongation coupling.

Lee B, Wu CY, Lin YW, Park SW, Wei LN.

Nucleic Acids Res. 2016 Sep 19;44(16):7568-79. doi: 10.1093/nar/gkw392. Epub 2016 May 10.


Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9.

Englert NA, Luo G, Goldstein JA, Surapureddi S.

J Biol Chem. 2015 Jan 23;290(4):2264-78. doi: 10.1074/jbc.M114.579474. Epub 2014 Nov 12.


Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity.

Chu Y, Gómez Rosso L, Huang P, Wang Z, Xu Y, Yao X, Bao M, Yan J, Song H, Wang G.

Cell Res. 2014 Oct;24(10):1250-65. doi: 10.1038/cr.2014.120. Epub 2014 Sep 16.


Med25 is required for estrogen receptor alpha (ERα)-mediated regulation of human CYP2C9 expression.

Shi Z, Yang W, Goldstein JA, Zhang SY.

Biochem Pharmacol. 2014 Aug 15;90(4):425-31. doi: 10.1016/j.bcp.2014.06.016. Epub 2014 Jun 21.


Kin28 regulates the transient association of Mediator with core promoters.

Jeronimo C, Robert F.

Nat Struct Mol Biol. 2014 May;21(5):449-55. doi: 10.1038/nsmb.2810. Epub 2014 Apr 6.


Liver-type fatty acid binding protein interacts with hepatocyte nuclear factor 4α.

McIntosh AL, Petrescu AD, Hostetler HA, Kier AB, Schroeder F.

FEBS Lett. 2013 Nov 29;587(23):3787-91. doi: 10.1016/j.febslet.2013.09.043. Epub 2013 Oct 15.


The Mediator complex and transcription regulation.

Poss ZC, Ebmeier CC, Taatjes DJ.

Crit Rev Biochem Mol Biol. 2013 Nov-Dec;48(6):575-608. doi: 10.3109/10409238.2013.840259. Epub 2013 Oct 3. Review.


Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

Kaikkonen MU, Spann NJ, Heinz S, Romanoski CE, Allison KA, Stender JD, Chun HB, Tough DF, Prinjha RK, Benner C, Glass CK.

Mol Cell. 2013 Aug 8;51(3):310-25. doi: 10.1016/j.molcel.2013.07.010.


The Mediator Complex and Lipid Metabolism.

Zhang Y, Xiaoli, Zhao X, Yang F.

J Biochem Pharmacol Res. 2013 Mar;1(1):51-55.


The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members.

Verger A, Baert JL, Verreman K, Dewitte F, Ferreira E, Lens Z, de Launoit Y, Villeret V, Monté D.

Nucleic Acids Res. 2013 May;41(9):4847-59. doi: 10.1093/nar/gkt199. Epub 2013 Mar 26.


Proteasome-mediated turnover of Arabidopsis MED25 is coupled to the activation of FLOWERING LOCUS T transcription.

Iñigo S, Giraldez AN, Chory J, Cerdán PD.

Plant Physiol. 2012 Nov;160(3):1662-73. doi: 10.1104/pp.112.205500. Epub 2012 Sep 19.


MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells.

Han EH, Rha GB, Chi YI.

PLoS One. 2012;7(8):e44007. doi: 10.1371/journal.pone.0044007. Epub 2012 Aug 30.


The Arabidopsis mediator subunit MED25 differentially regulates jasmonate and abscisic acid signaling through interacting with the MYC2 and ABI5 transcription factors.

Chen R, Jiang H, Li L, Zhai Q, Qi L, Zhou W, Liu X, Li H, Zheng W, Sun J, Li C.

Plant Cell. 2012 Jul;24(7):2898-916. doi: 10.1105/tpc.112.098277. Epub 2012 Jul 20.


Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver.

Zhang SY, Surapureddi S, Coulter S, Ferguson SS, Goldstein JA.

Mol Pharmacol. 2012 Sep;82(3):529-40. doi: 10.1124/mol.112.078386. Epub 2012 Jun 20.


Charcot-Marie-Tooth disease and intracellular traffic.

Bucci C, Bakke O, Progida C.

Prog Neurobiol. 2012 Dec;99(3):191-225. doi: 10.1016/j.pneurobio.2012.03.003. Epub 2012 Mar 22. Review.

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