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Items: 1 to 20 of 103


Localization Microscopy Analyses of MRE11 Clusters in 3D-Conserved Cell Nuclei of Different Cell Lines.

Eryilmaz M, Schmitt E, Krufczik M, Theda F, Lee JH, Cremer C, Bestvater F, Schaufler W, Hausmann M, Hildenbrand G.

Cancers (Basel). 2018 Jan 22;10(1). pii: E25. doi: 10.3390/cancers10010025.


Physiological protein blocks direct the Mre11-Rad50-Xrs2 and Sae2 nuclease complex to initiate DNA end resection.

Reginato G, Cannavo E, Cejka P.

Genes Dev. 2017 Dec 1;31(23-24):2325-2330. doi: 10.1101/gad.308254.117. Epub 2018 Jan 10.


Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

Lu H, Shamanna RA, de Freitas JK, Okur M, Khadka P, Kulikowicz T, Holland PP, Tian J, Croteau DL, Davis AJ, Bohr VA.

Nat Commun. 2017 Dec 11;8(1):2039. doi: 10.1038/s41467-017-02146-3.


The end-joining factor Ku acts in the end-resection of double strand break-free arrested replication forks.

Teixeira-Silva A, Ait Saada A, Hardy J, Iraqui I, Nocente MC, Fréon K, Lambert SAE.

Nat Commun. 2017 Dec 7;8(1):1982. doi: 10.1038/s41467-017-02144-5.


Sgs1 Binding to Rad51 Stimulates Homology-Directed DNA Repair in Saccharomyces cerevisiae.

Campos-Doerfler L, Syed S, Schmidt KH.

Genetics. 2018 Jan;208(1):125-138. doi: 10.1534/genetics.117.300545. Epub 2017 Nov 21.


AUNIP/C1orf135 directs DNA double-strand breaks towards the homologous recombination repair pathway.

Lou J, Chen H, Han J, He H, Huen MSY, Feng XH, Liu T, Huang J.

Nat Commun. 2017 Oct 17;8(1):985. doi: 10.1038/s41467-017-01151-w.


MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.

Lemaçon D, Jackson J, Quinet A, Brickner JR, Li S, Yazinski S, You Z, Ira G, Zou L, Mosammaparast N, Vindigni A.

Nat Commun. 2017 Oct 16;8(1):860. doi: 10.1038/s41467-017-01180-5.


A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining.

Runge KW, Li Y.

Curr Genet. 2018 Apr;64(2):359-364. doi: 10.1007/s00294-017-0760-1. Epub 2017 Oct 10. Review.


Dna2 initiates resection at clean DNA double-strand breaks.

Paudyal SC, Li S, Yan H, Hunter T, You Z.

Nucleic Acids Res. 2017 Nov 16;45(20):11766-11781. doi: 10.1093/nar/gkx830.


Genetic Separation of Sae2 Nuclease Activity from Mre11 Nuclease Functions in Budding Yeast.

Arora S, Deshpande RA, Budd M, Campbell J, Revere A, Zhang X, Schmidt KH, Paull TT.

Mol Cell Biol. 2017 Nov 28;37(24). pii: e00156-17. doi: 10.1128/MCB.00156-17. Print 2017 Dec 15.


Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair.

Myler LR, Gallardo IF, Soniat MM, Deshpande RA, Gonzalez XB, Kim Y, Paull TT, Finkelstein IJ.

Mol Cell. 2017 Sep 7;67(5):891-898.e4. doi: 10.1016/j.molcel.2017.08.002. Epub 2017 Aug 31.


Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.

Hollingworth R, Horniblow RD, Forrest C, Stewart GS, Grand RJ.

J Virol. 2017 Oct 27;91(22). pii: e00930-17. doi: 10.1128/JVI.00930-17. Print 2017 Nov 15.


SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.

Daddacha W, Koyen AE, Bastien AJ, Head PE, Dhere VR, Nabeta GN, Connolly EC, Werner E, Madden MZ, Daly MB, Minten EV, Whelan DR, Schlafstein AJ, Zhang H, Anand R, Doronio C, Withers AE, Shepard C, Sundaram RK, Deng X, Dynan WS, Wang Y, Bindra RS, Cejka P, Rothenberg E, Doetsch PW, Kim B, Yu DS.

Cell Rep. 2017 Aug 22;20(8):1921-1935. doi: 10.1016/j.celrep.2017.08.008.


DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair.

Tomimatsu N, Mukherjee B, Harris JL, Boffo FL, Hardebeck MC, Potts PR, Khanna KK, Burma S.

J Biol Chem. 2017 Jun 30;292(26):10779-10790. doi: 10.1074/jbc.M116.772475. Epub 2017 May 17.


Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe.

Li Y, Wang J, Zhou G, Lajeunesse M, Le N, Stawicki BN, Corcino YL, Berkner KL, Runge KW.

Genetics. 2017 May;206(1):481-496. doi: 10.1534/genetics.117.200972. Epub 2017 Mar 14.


A global view of meiotic double-strand break end resection.

Mimitou EP, Yamada S, Keeney S.

Science. 2017 Jan 6;355(6320):40-45. doi: 10.1126/science.aak9704.


Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks.

Kim HS, Williamson EA, Nickoloff JA, Hromas RA, Lee SH.

J Biol Chem. 2017 Jan 27;292(4):1414-1425. doi: 10.1074/jbc.M116.745646. Epub 2016 Dec 14.


Nucleolytic processing of aberrant replication intermediates by an Exo1-Dna2-Sae2 axis counteracts fork collapse-driven chromosome instability.

Colosio A, Frattini C, Pellicanò G, Villa-Hernández S, Bermejo R.

Nucleic Acids Res. 2016 Dec 15;44(22):10676-10690. Epub 2016 Sep 26.


Eukaryotic resectosomes: A single-molecule perspective.

Myler LR, Finkelstein IJ.

Prog Biophys Mol Biol. 2017 Aug;127:119-129. doi: 10.1016/j.pbiomolbio.2016.08.001. Epub 2016 Aug 3. Review.


β2-spectrin depletion impairs DNA damage repair.

Horikoshi N, Pandita RK, Mujoo K, Hambarde S, Sharma D, Mattoo AR, Chakraborty S, Charaka V, Hunt CR, Pandita TK.

Oncotarget. 2016 Jun 7;7(23):33557-70. doi: 10.18632/oncotarget.9677.

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