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Items: 1 to 20 of 55

1.

Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.

Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP.

Cell. 2017 Jun 15;169(7):1303-1314.e18. doi: 10.1016/j.cell.2017.05.025. Epub 2017 Jun 8.

2.

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.

Steinman JB, Santarossa CC, Miller RM, Yu LS, Serpinskaya AS, Furukawa H, Morimoto S, Tanaka Y, Nishitani M, Asano M, Zalyte R, Ondrus AE, Johnson AG, Ye F, Nachury MV, Fukase Y, Aso K, Foley MA, Gelfand VI, Chen JK, Carter AP, Kapoor TM.

Elife. 2017 May 19;6. pii: e25174. doi: 10.7554/eLife.25174.

3.

Lissencephaly-1 is a context-dependent regulator of the human dynein complex.

Baumbach J, Murthy A, McClintock MA, Dix CI, Zalyte R, Hoang HT, Bullock SL.

Elife. 2017 Apr 13;6. pii: e21768. doi: 10.7554/eLife.21768.

4.

Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution.

Yogev S, Maeder CI, Cooper R, Horowitz M, Hendricks AG, Shen K.

Nat Commun. 2017 Apr 13;8:15063. doi: 10.1038/ncomms15063.

5.

Single Molecule Investigation of Kinesin-1 Motility Using Engineered Microtubule Defects.

Gramlich MW, Conway L, Liang WH, Labastide JA, King SJ, Xu J, Ross JL.

Sci Rep. 2017 Mar 13;7:44290. doi: 10.1038/srep44290.

6.

DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes.

Hoang HT, Schlager MA, Carter AP, Bullock SL.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1597-E1606. doi: 10.1073/pnas.1620141114. Epub 2017 Feb 14.

7.

Mechanism of nuclear movements in a multinucleated cell.

Gibeaux R, Politi AZ, Philippsen P, Nédélec F.

Mol Biol Cell. 2017 Mar 1;28(5):645-660. doi: 10.1091/mbc.E16-11-0806. Epub 2017 Jan 11.

8.

The mammalian dynein-dynactin complex is a strong opponent to kinesin in a tug-of-war competition.

Belyy V, Schlager MA, Foster H, Reimer AE, Carter AP, Yildiz A.

Nat Cell Biol. 2016 Sep;18(9):1018-24. doi: 10.1038/ncb3393. Epub 2016 Jul 25.

9.

Quantitative Determination of the Probability of Multiple-Motor Transport in Bead-Based Assays.

Li Q, King SJ, Gopinathan A, Xu J.

Biophys J. 2016 Jun 21;110(12):2720-8. doi: 10.1016/j.bpj.2016.05.015.

10.

Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis.

Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan YN.

Neuron. 2016 May 4;90(3):551-63. doi: 10.1016/j.neuron.2016.03.027. Epub 2016 Apr 21.

11.

Importance of anisotropy in detachment rates for force production and cargo transport by a team of motor proteins.

Takshak A, Kunwar A.

Protein Sci. 2016 May;25(5):1075-9. doi: 10.1002/pro.2905. Epub 2016 Mar 16.

12.

Axon Transport and Neuropathy: Relevant Perspectives on the Etiopathogenesis of Familial Dysautonomia.

Tourtellotte WG.

Am J Pathol. 2016 Mar;186(3):489-99. doi: 10.1016/j.ajpath.2015.10.022. Epub 2015 Dec 24. Review.

13.

Nanoparticle-assisted optical tethering of endosomes reveals the cooperative function of dyneins in retrograde axonal transport.

Chowdary PD, Che DL, Kaplan L, Chen O, Pu K, Bawendi M, Cui B.

Sci Rep. 2015 Dec 10;5:18059. doi: 10.1038/srep18059.

14.

The Altered Hepatic Tubulin Code in Alcoholic Liver Disease.

Groebner JL, Tuma PL.

Biomolecules. 2015 Sep 18;5(3):2140-59. doi: 10.3390/biom5032140. Review.

15.

Impact-Free Measurement of Microtubule Rotations on Kinesin and Cytoplasmic-Dynein Coated Surfaces.

Mitra A, Ruhnow F, Nitzsche B, Diez S.

PLoS One. 2015 Sep 14;10(9):e0136920. doi: 10.1371/journal.pone.0136920. eCollection 2015.

16.

Retrograde NGF axonal transport--motor coordination in the unidirectional motility regime.

Chowdary PD, Che DL, Zhang K, Cui B.

Biophys J. 2015 Jun 2;108(11):2691-703. doi: 10.1016/j.bpj.2015.04.036.

17.

Cytoplasmic dynein and early endosome transport.

Xiang X, Qiu R, Yao X, Arst HN Jr, Peñalva MA, Zhang J.

Cell Mol Life Sci. 2015 Sep;72(17):3267-80. doi: 10.1007/s00018-015-1926-y. Epub 2015 May 23. Review.

18.

Control of cytoplasmic dynein force production and processivity by its C-terminal domain.

Nicholas MP, Höök P, Brenner S, Wynne CL, Vallee RB, Gennerich A.

Nat Commun. 2015 Feb 11;6:6206. doi: 10.1038/ncomms7206.

19.

Distinct functional roles of cytoplasmic dynein defined by the intermediate chain isoforms.

Pfister KK.

Exp Cell Res. 2015 May 15;334(1):54-60. doi: 10.1016/j.yexcr.2014.12.013. Epub 2015 Jan 6. Review.

20.

Cooperative protofilament switching emerges from inter-motor interference in multiple-motor transport.

Ando D, Mattson MK, Xu J, Gopinathan A.

Sci Rep. 2014 Dec 1;4:7255. doi: 10.1038/srep07255.

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