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Items: 1 to 20 of 328


Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury.

Souza T, Trairatphisan P, Piñero J, Furlong LI, Saez-Rodriguez J, Kleinjans J, Jennen D.

Front Genet. 2018 Nov 20;9:527. doi: 10.3389/fgene.2018.00527. eCollection 2018.


Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a.

Cheng Y, Wang ZM, Tan W, Wang X, Li Y, Bai B, Li Y, Zhang SF, Yan HL, Chen ZL, Liu CM, Mi TW, Xia S, Zhou Z, Liu A, Tang GB, Liu C, Dai ZJ, Wang YY, Wang H, Wang X, Kang Y, Lin L, Chen Z, Xie N, Sun Q, Xie W, Peng J, Chen D, Teng ZQ, Jin P.

Nat Neurosci. 2018 Dec;21(12):1689-1703. doi: 10.1038/s41593-018-0261-7. Epub 2018 Nov 5.


Using set theory to reduce redundancy in pathway sets.

Stoney RA, Schwartz JM, Robertson DL, Nenadic G.

BMC Bioinformatics. 2018 Oct 19;19(1):386. doi: 10.1186/s12859-018-2355-3.


Typing tumors using pathways selected by somatic evolution.

Wang S, Ma J, Zhang W, Shen JP, Huang J, Peng J, Ideker T.

Nat Commun. 2018 Oct 8;9(1):4159. doi: 10.1038/s41467-018-06464-y.


Computational identification and analysis of neurodegenerative disease associated protein kinases in hominid genomes.

Jayapalan S, Subramanian D, Natarajan J.

Genes Dis. 2016 Apr 23;3(3):228-237. doi: 10.1016/j.gendis.2016.04.004. eCollection 2016 Sep.


The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells.

Olney KC, Nyer DB, Vargas DA, Wilson Sayres MA, Haynes KA.

BMC Syst Biol. 2018 Sep 25;12(1):83. doi: 10.1186/s12918-018-0608-4.


Erianin inhibits human cervical cancer cell through regulation of tumor protein p53 via the extracellular signal-regulated kinase signaling pathway.

Li M, He Y, Peng C, Xie X, Hu G.

Oncol Lett. 2018 Oct;16(4):5006-5012. doi: 10.3892/ol.2018.9267. Epub 2018 Aug 3.


A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.

Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Delahaye-Duriez A, Steenwinckel JV, Gressens P, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Cardenas A, Vanclef F, Laaniste L, Niespodziany I, Keaney J, Gasser J, Gillet G, Shkura K, Chong SA, Behmoaras J, Kadiu I, Petretto E, Kaminski RM, Johnson MR.

Nat Commun. 2018 Sep 3;9(1):3561. doi: 10.1038/s41467-018-06008-4.


A DNA-Methylated Sight on Autoimmune Inflammation Network across RA, pSS, and SLE.

Wang X, Lei D, Ding J, Liu S, Tao L, Zhang F, Peng J, Xu J.

J Immunol Res. 2018 Aug 12;2018:4390789. doi: 10.1155/2018/4390789. eCollection 2018.


A New Strategy to Uncover the Anticancer Mechanism of Chinese Compound Formula by Integrating Systems Pharmacology and Bioinformatics.

Dai Y, Sun L, Qiang W.

Evid Based Complement Alternat Med. 2018 Jul 18;2018:6707850. doi: 10.1155/2018/6707850. eCollection 2018.


Differentially expressed genes related to major depressive disorder and antidepressant response: genome-wide gene expression analysis.

Woo HI, Lim SW, Myung W, Kim DK, Lee SY.

Exp Mol Med. 2018 Aug 3;50(8):92. doi: 10.1038/s12276-018-0123-0.


INBIA: a boosting methodology for proteomic network inference.

Sardina DS, Micale G, Ferro A, Pulvirenti A, Giugno R.

BMC Bioinformatics. 2018 Jul 9;19(Suppl 7):188. doi: 10.1186/s12859-018-2183-5.


NetControl4BioMed: a pipeline for biomedical data acquisition and analysis of network controllability.

Kanhaiya K, Rogojin V, Kazemi K, Czeizler E, Petre I.

BMC Bioinformatics. 2018 Jul 9;19(Suppl 7):185. doi: 10.1186/s12859-018-2177-3.


CIGene: a literature-based online resource for cancer initiation genes.

Liu Y, Luo M, Li Q, Lu J, Zhao M, Qu H.

BMC Genomics. 2018 Jul 25;19(1):552. doi: 10.1186/s12864-018-4944-y.


Assessment of the key regulatory genes and their Interologs for Turner Syndrome employing network approach.

Farooqui A, Tazyeen S, Ahmed MM, Alam A, Ali S, Malik MZ, Ali S, Ishrat R.

Sci Rep. 2018 Jul 4;8(1):10091. doi: 10.1038/s41598-018-28375-0.


Time Dependent Pathway Activation of Signalling Cascades in Rat Organs after Short-Term Hyperoxia.

Hinkelbein J, Braunecker S, Danz M, Böhm L, Hohn A.

Int J Mol Sci. 2018 Jul 4;19(7). pii: E1960. doi: 10.3390/ijms19071960.


Inference of patient-specific subpathway activities reveals a functional signature associated with the prognosis of patients with breast cancer.

Han J, Liu S, Jiang Y, Xu C, Zheng B, Jiang M, Yang H, Su F, Li C, Zhang Y.

J Cell Mol Med. 2018 Sep;22(9):4304-4316. doi: 10.1111/jcmm.13720. Epub 2018 Jul 4.


FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining.

Bachman JA, Gyori BM, Sorger PK.

BMC Bioinformatics. 2018 Jun 28;19(1):248. doi: 10.1186/s12859-018-2211-5.


Classifying tumors by supervised network propagation.

Zhang W, Ma J, Ideker T.

Bioinformatics. 2018 Jul 1;34(13):i484-i493. doi: 10.1093/bioinformatics/bty247.

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