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Items: 1 to 20 of 72


The Intra-S Checkpoint Responses to DNA Damage.

Iyer DR, Rhind N.

Genes (Basel). 2017 Feb 17;8(2). pii: E74. doi: 10.3390/genes8020074. Review.


Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosis.

Princz LN, Wild P, Bittmann J, Aguado FJ, Blanco MG, Matos J, Pfander B.

EMBO J. 2017 Mar 1;36(5):664-678. doi: 10.15252/embj.201694831. Epub 2017 Jan 17.


A Positive Amplification Mechanism Involving a Kinase and Replication Initiation Factor Helps Assemble the Replication Fork Helicase.

Bruck I, Dhingra N, Kaplan DL.

J Biol Chem. 2017 Feb 24;292(8):3062-3073. doi: 10.1074/jbc.M116.772368. Epub 2017 Jan 12.


Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation.

Hiraga SI, Ly T, Garzón J, Hořejší Z, Ohkubo YN, Endo A, Obuse C, Boulton SJ, Lamond AI, Donaldson AD.

EMBO Rep. 2017 Mar;18(3):403-419. doi: 10.15252/embr.201641983. Epub 2017 Jan 11.


Mechanisms Governing DDK Regulation of the Initiation of DNA Replication.

Larasati, Duncker BP.

Genes (Basel). 2016 Dec 22;8(1). pii: E3. doi: 10.3390/genes8010003. Review.


TIMELESS Suppresses the Accumulation of Aberrant CDC45·MCM2-7·GINS Replicative Helicase Complexes on Human Chromatin.

Xu X, Wang JT, Li M, Liu Y.

J Biol Chem. 2016 Oct 21;291(43):22544-22558. Epub 2016 Sep 1.


Chromosome Duplication in Saccharomyces cerevisiae.

Bell SP, Labib K.

Genetics. 2016 Jul;203(3):1027-67. doi: 10.1534/genetics.115.186452. Review.


Sld3-MCM Interaction Facilitated by Dbf4-Dependent Kinase Defines an Essential Step in Eukaryotic DNA Replication Initiation.

Fang D, Cao Q, Lou H.

Front Microbiol. 2016 Jun 10;7:885. doi: 10.3389/fmicb.2016.00885. eCollection 2016.


Structural Mechanisms of Hexameric Helicase Loading, Assembly, and Unwinding.

Trakselis MA.

F1000Res. 2016 Jan 27;5. pii: F1000 Faculty Rev-111. doi: 10.12688/f1000research.7509.1. eCollection 2016. Review.


Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation.

Deegan TD, Yeeles JT, Diffley JF.

EMBO J. 2016 May 2;35(9):961-73. doi: 10.15252/embj.201593552. Epub 2016 Feb 24.


A new MCM modification cycle regulates DNA replication initiation.

Wei L, Zhao X.

Nat Struct Mol Biol. 2016 Mar;23(3):209-16. doi: 10.1038/nsmb.3173. Epub 2016 Feb 8.


Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression.

Sheu YJ, Kinney JB, Stillman B.

Genome Res. 2016 Mar;26(3):315-30. doi: 10.1101/gr.195248.115. Epub 2016 Jan 5.


Insights into the Initiation of Eukaryotic DNA Replication.

Bruck I, Perez-Arnaiz P, Colbert MK, Kaplan DL.

Nucleus. 2015;6(6):449-54. doi: 10.1080/19491034.2015.1115938. Epub 2015 Dec 28.


Phosphorylation of the Synaptonemal Complex Protein Zip1 Regulates the Crossover/Noncrossover Decision during Yeast Meiosis.

Chen X, Suhandynata RT, Sandhu R, Rockmill B, Mohibullah N, Niu H, Liang J, Lo HC, Miller DE, Zhou H, Börner GV, Hollingsworth NM.

PLoS Biol. 2015 Dec 18;13(12):e1002329. doi: 10.1371/journal.pbio.1002329. eCollection 2015 Dec.


The Helicase Activity of Hyperthermophilic Archaeal MCM is Enhanced at High Temperatures by Lysine Methylation.

Xia Y, Niu Y, Cui J, Fu Y, Chen XS, Lou H, Cao Q.

Front Microbiol. 2015 Nov 9;6:1247. doi: 10.3389/fmicb.2015.01247. eCollection 2015.


S phase block following MEC1ATR inactivation occurs without severe dNTP depletion.

Earp C, Rowbotham S, Merényi G, Chabes A, Cha RS.

Biol Open. 2015 Nov 24;4(12):1739-43. doi: 10.1242/bio.015347.


The Replication Initiation Protein Sld3/Treslin Orchestrates the Assembly of the Replication Fork Helicase during S Phase.

Bruck I, Kaplan DL.

J Biol Chem. 2015 Nov 6;290(45):27414-24. doi: 10.1074/jbc.M115.688424. Epub 2015 Sep 24. Retraction in: J Biol Chem. 2017 Jun 16;292(24):10319.


Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase.

Buisson R, Boisvert JL, Benes CH, Zou L.

Mol Cell. 2015 Sep 17;59(6):1011-24. doi: 10.1016/j.molcel.2015.07.029. Epub 2015 Sep 10.


A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase.

Herrera MC, Tognetti S, Riera A, Zech J, Clarke P, Fernández-Cid A, Speck C.

Nucleic Acids Res. 2015 Dec 2;43(21):10238-50. doi: 10.1093/nar/gkv881. Epub 2015 Sep 3.


Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena.

Sandoval PY, Lee PH, Meng X, Kapler GM.

PLoS Genet. 2015 Jul 28;11(7):e1005405. doi: 10.1371/journal.pgen.1005405. eCollection 2015 Jul.

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