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Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial.

Writing Group for the TRIGR Study Group, Knip M, Åkerblom HK, Al Taji E, Becker D, Bruining J, Castano L, Danne T, de Beaufort C, Dosch HM, Dupre J, Fraser WD, Howard N, Ilonen J, Konrad D, Kordonouri O, Krischer JP, Lawson ML, Ludvigsson J, Madacsy L, Mahon JL, Ormisson A, Palmer JP, Pozzilli P, Savilahti E, Serrano-Rios M, Songini M, Taback S, Vaarala O, White NH, Virtanen SM, Wasikowa R.

JAMA. 2018 Jan 2;319(1):38-48. doi: 10.1001/jama.2017.19826.


Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction.

Borg DJ, Yap FYT, Keshvari S, Simmons DG, Gallo LA, Fotheringham AK, Zhuang A, Slattery RM, Hasnain SZ, Coughlan MT, Kantharidis P, Forbes JM.

Islets. 2018 Jan 2;10(1):10-24. doi: 10.1080/19382014.2017.1405189. Epub 2017 Dec 22.


Old Fashioned vs. Ultra-Processed-Based Current Diets: Possible Implication in the Increased Susceptibility to Type 1 Diabetes and Celiac Disease in Childhood.

Aguayo-Patrón SV, Calderón de la Barca AM.

Foods. 2017 Nov 15;6(11). pii: E100. doi: 10.3390/foods6110100. Review.


Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development.

Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, Herold KC, Wen L, Flavell RA.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10443-10448. doi: 10.1073/pnas.1705599114. Epub 2017 Sep 11.


Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.

Zhao G, Vatanen T, Droit L, Park A, Kostic AD, Poon TW, Vlamakis H, Siljander H, Härkönen T, Hämäläinen AM, Peet A, Tillmann V, Ilonen J, Wang D, Knip M, Xavier RJ, Virgin HW.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6166-E6175. doi: 10.1073/pnas.1706359114. Epub 2017 Jul 10.


Combination Immunotherapy for Type 1 Diabetes.

Bone RN, Evans-Molina C.

Curr Diab Rep. 2017 Jul;17(7):50. doi: 10.1007/s11892-017-0878-z. Review.


A1 beta-casein milk protein and other environmental pre-disposing factors for type 1 diabetes.

Chia JSJ, McRae JL, Kukuljan S, Woodford K, Elliott RB, Swinburn B, Dwyer KM.

Nutr Diabetes. 2017 May 15;7(5):e274. doi: 10.1038/nutd.2017.16. Review.


First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study.

Hummel S, Beyerlein A, Tamura R, Uusitalo U, Andrén Aronsson C, Yang J, Riikonen A, Lernmark Å, Rewers MJ, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Virtanen SM, Norris JM; TEDDY Study Group.

Diabetes Care. 2017 Mar;40(3):398-404. doi: 10.2337/dc16-1624. Epub 2017 Jan 17.


Environmental control of autoimmune inflammation in the central nervous system.

Rothhammer V, Quintana FJ.

Curr Opin Immunol. 2016 Dec;43:46-53. doi: 10.1016/j.coi.2016.09.002. Epub 2016 Oct 4. Review.


Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes.

Galli E, Härkönen T, Sainio MT, Ustav M, Toots U, Urtti A, Yliperttula M, Lindahl M, Knip M, Saarma M, Lindholm P.

Sci Rep. 2016 Jun 30;6:29058. doi: 10.1038/srep29058.


Environmental risk factors for type 1 diabetes.

Rewers M, Ludvigsson J.

Lancet. 2016 Jun 4;387(10035):2340-2348. doi: 10.1016/S0140-6736(16)30507-4. Review.


Blood-based signatures in type 1 diabetes.

Cabrera SM, Chen YG, Hagopian WA, Hessner MJ.

Diabetologia. 2016 Mar;59(3):414-25. doi: 10.1007/s00125-015-3843-x. Epub 2015 Dec 23. Review.


Characterization of human organ donors testing positive for type 1 diabetes-associated autoantibodies.

Wiberg A, Granstam A, Ingvast S, Härkönen T, Knip M, Korsgren O, Skog O.

Clin Exp Immunol. 2015 Dec;182(3):278-88. doi: 10.1111/cei.12698. Epub 2015 Oct 6.


Detection of Antibodies against Human and Plant Aquaporins in Patients with Multiple Sclerosis.

Vojdani A, Mukherjee PS, Berookhim J, Kharrazian D.

Autoimmune Dis. 2015;2015:905208. doi: 10.1155/2015/905208. Epub 2015 Jul 26.


The role for gut permeability in the pathogenesis of type 1 diabetes--a solid or leaky concept?

Li X, Atkinson MA.

Pediatr Diabetes. 2015 Nov;16(7):485-92. doi: 10.1111/pedi.12305. Epub 2015 Aug 13. Review.


Infant Feeding and Timing of Complementary Foods in the Development of Type 1 Diabetes.

Nucci AM, Virtanen SM, Becker DJ.

Curr Diab Rep. 2015 Sep;15(9):62. doi: 10.1007/s11892-015-0628-z. Review.


Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at prevention.

Michels A, Zhang L, Khadra A, Kushner JA, Redondo MJ, Pietropaolo M.

Pediatr Diabetes. 2015 Nov;16(7):465-84. doi: 10.1111/pedi.12299. Epub 2015 Jul 23. Review.


Diabetes mellitus: The epidemic of the century.

Kharroubi AT, Darwish HM.

World J Diabetes. 2015 Jun 25;6(6):850-67. doi: 10.4239/wjd.v6.i6.850. Review.


Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease.

Atkinson MA, von Herrath M, Powers AC, Clare-Salzler M.

Diabetes Care. 2015 Jun;38(6):979-88. doi: 10.2337/dc15-0144. No abstract available.


Luminex and other multiplex high throughput technologies for the identification of, and host response to, environmental triggers of type 1 diabetes.

Purohit S, Sharma A, She JX.

Biomed Res Int. 2015;2015:326918. doi: 10.1155/2015/326918. Epub 2015 Mar 25. Review.

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