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Items: 1 to 20 of 49

1.

Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice.

Hoopes SL, Gruzdev A, Edin ML, Graves JP, Bradbury JA, Flake GP, Lih FB, DeGraff LM, Zeldin DC.

PLoS One. 2017 Apr 6;12(4):e0175348. doi: 10.1371/journal.pone.0175348. eCollection 2017.

2.

Pro-Resolving Molecules-New Approaches to Treat Sepsis?

Buechler C, Pohl R, Aslanidis C.

Int J Mol Sci. 2017 Feb 23;18(3). pii: E476. doi: 10.3390/ijms18030476. Review.

3.

Soluble epoxide hydrolase deficiency or inhibition enhances murine hypoxic pulmonary vasoconstriction after lipopolysaccharide challenge.

Wepler M, Beloiartsev A, Buswell MD, Panigrahy D, Malhotra R, Buys ES, Radermacher P, Ichinose F, Bloch DB, Zapol WM.

Am J Physiol Lung Cell Mol Physiol. 2016 Dec 1;311(6):L1213-L1221. doi: 10.1152/ajplung.00394.2016. Epub 2016 Nov 4.

PMID:
27815261
4.

Effects of a Soluble Epoxide Hydrolase Inhibitor on Lipopolysaccharide-Induced Acute Lung Injury in Mice.

Tao W, Li PS, Yang LQ, Ma YB.

PLoS One. 2016 Aug 4;11(8):e0160359. doi: 10.1371/journal.pone.0160359. eCollection 2016.

5.

Epoxyeicosatrienoic Acids and 20-Hydroxyeicosatetraenoic Acid on Endothelial and Vascular Function.

Imig JD.

Adv Pharmacol. 2016;77:105-41. doi: 10.1016/bs.apha.2016.04.003. Epub 2016 May 5.

6.

Characterization of the Cytochrome P450 epoxyeicosanoid pathway in non-alcoholic steatohepatitis.

Wells MA, Vendrov KC, Edin ML, Ferslew BC, Zha W, Nguyen BK, Church RJ, Lih FB, DeGraff LM, Brouwer KL, Barritt AS 4th, Zeldin DC, Lee CR.

Prostaglandins Other Lipid Mediat. 2016 Sep;125:19-29. doi: 10.1016/j.prostaglandins.2016.07.002. Epub 2016 Jul 9.

7.

CYP450-derived oxylipins mediate inflammatory resolution.

Gilroy DW, Edin ML, De Maeyer RP, Bystrom J, Newson J, Lih FB, Stables M, Zeldin DC, Bishop-Bailey D.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3240-9. doi: 10.1073/pnas.1521453113. Epub 2016 May 25.

8.

11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of membrane depolarization.

Sun C, Simon SI, Foster GA, Radecke CE, Hwang HV, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA.

J Mol Cell Cardiol. 2016 May;94:180-188. doi: 10.1016/j.yjmcc.2016.03.019. Epub 2016 Apr 11.

9.

Alcohol produces distinct hepatic lipidome and eicosanoid signature in lean and obese.

Puri P, Xu J, Vihervaara T, Katainen R, Ekroos K, Daita K, Min HK, Joyce A, Mirshahi F, Tsukamoto H, Sanyal AJ.

J Lipid Res. 2016 Jun;57(6):1017-28. doi: 10.1194/jlr.M066175. Epub 2016 Mar 28.

10.

CYP Genetic Variants, CYP Metabolite Levels, and Symptomatic Carotid Stenosis in Ischemic Stroke Patients.

Yi X, Liao D, Wu L, Chen H, Li J, Wang C.

J Atheroscler Thromb. 2016 May 2;23(5):621-31. doi: 10.5551/jat.32714. Epub 2015 Dec 19.

11.

Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins.

Thomson S, Edin ML, Lih FB, Davies M, Yaqoob MM, Hammock BD, Gilroy D, Zeldin DC, Bishop-Bailey D.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):774-80. doi: 10.1016/j.bbrc.2015.06.012. Epub 2015 Jun 15.

12.

Soluble Epoxide Hydrolase in Hydrocephalus, Cerebral Edema, and Vascular Inflammation After Subarachnoid Hemorrhage.

Siler DA, Berlow YA, Kukino A, Davis CM, Nelson JW, Grafe MR, Ono H, Cetas JS, Pike M, Alkayed NJ.

Stroke. 2015 Jul;46(7):1916-22. doi: 10.1161/STROKEAHA.114.008560. Epub 2015 May 19.

13.

Macrophage epoxygenase determines a profibrotic transcriptome signature.

Behmoaras J, Diaz AG, Venda L, Ko JH, Srivastava P, Montoya A, Faull P, Webster Z, Moyon B, Pusey CD, Abraham DJ, Petretto E, Cook TH, Aitman TJ.

J Immunol. 2015 May 15;194(10):4705-4716. doi: 10.4049/jimmunol.1402979. Epub 2015 Apr 3.

14.

Epoxyeicosatrienoic acids regulate macrophage polarization and prevent LPS-induced cardiac dysfunction.

Dai M, Wu L, He Z, Zhang S, Chen C, Xu X, Wang P, Gruzdev A, Zeldin DC, Wang DW.

J Cell Physiol. 2015 Sep;230(9):2108-19. doi: 10.1002/jcp.24939.

15.

Epoxyeicosatrienoic acids, hypertension, and kidney injury.

Imig JD.

Hypertension. 2015 Mar;65(3):476-82. doi: 10.1161/HYPERTENSIONAHA.114.03585. Epub 2015 Jan 12. Review. No abstract available.

16.

CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice.

Chen G, Xu R, Zhang S, Wang Y, Wang P, Edin ML, Zeldin DC, Wang DW.

Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E97-E110. doi: 10.1152/ajpendo.00366.2014. Epub 2014 Nov 11.

17.

CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.

Abraham NG, Sodhi K, Silvis AM, Vanella L, Favero G, Rezzani R, Lee C, Zeldin DC, Schwartzman ML.

Hypertension. 2014 Dec;64(6):1352-61. doi: 10.1161/HYPERTENSIONAHA.114.03884. Epub 2014 Sep 22.

18.

Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage.

Siler DA, Martini RP, Ward JP, Nelson JW, Borkar RN, Zuloaga KL, Liu JJ, Fairbanks SL, Raskin JS, Anderson VC, Dogan A, Wang RK, Alkayed NJ, Cetas JS.

Neurocrit Care. 2015 Apr;22(2):306-19. doi: 10.1007/s12028-014-0011-y.

19.

Functional characterization of cytochrome P450-derived epoxyeicosatrienoic acids in adipogenesis and obesity.

Zha W, Edin ML, Vendrov KC, Schuck RN, Lih FB, Jat JL, Bradbury JA, DeGraff LM, Hua K, Tomer KB, Falck JR, Zeldin DC, Lee CR.

J Lipid Res. 2014 Oct;55(10):2124-36. doi: 10.1194/jlr.M053199. Epub 2014 Aug 11.

20.

Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolism.

Spector AA, Kim HY.

Biochim Biophys Acta. 2015 Apr;1851(4):356-65. doi: 10.1016/j.bbalip.2014.07.020. Epub 2014 Aug 2. Review.

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