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Protein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection.

Raposo RA, Trudgian DC, Thomas B, van Wilgenburg B, Cowley SA, James W.

J Immunol. 2011 Jul 15;187(2):748-59. doi: 10.4049/jimmunol.1003678. Epub 2011 Jun 10.


Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase.

Laguette N, Brégnard C, Bouchet J, Benmerah A, Benichou S, Basmaciogullari S.

J Virol. 2009 Jul;83(14):7117-28. doi: 10.1128/JVI.01648-08. Epub 2009 May 13.


Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4.

Signoret N, Oldridge J, Pelchen-Matthews A, Klasse PJ, Tran T, Brass LF, Rosenkilde MM, Schwartz TW, Holmes W, Dallas W, Luther MA, Wells TN, Hoxie JA, Marsh M.

J Cell Biol. 1997 Nov 3;139(3):651-64.


Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.

Dietrich J, Kastrup J, Nielsen BL, Odum N, Geisler C.

J Cell Biol. 1997 Jul 28;138(2):271-81.


Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck.

Winkler DG, Park I, Kim T, Payne NS, Walsh CT, Strominger JL, Shin J.

Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5176-80.


The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network.

Ponnambalam S, Rabouille C, Luzio JP, Nilsson T, Warren G.

J Cell Biol. 1994 Apr;125(2):253-68.


Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes.

Schwartz O, Dautry-Varsat A, Goud B, Maréchal V, Subtil A, Heard JM, Danos O.

J Virol. 1995 Jan;69(1):528-33.

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