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Epigenetic Combinatorial Patterns Predict Disease Variants.

Zhang Y.

Front Genet. 2017 May 30;8:71. doi: 10.3389/fgene.2017.00071. eCollection 2017.


The Pancreatic Islet Regulome Browser.

Mularoni L, Ramos-Rodríguez M, Pasquali L.

Front Genet. 2017 Feb 14;8:13. doi: 10.3389/fgene.2017.00013. eCollection 2017.


Genomics of Islet (Dys)function and Type 2 Diabetes.

Lawlor N, Khetan S, Ucar D, Stitzel ML.

Trends Genet. 2017 Apr;33(4):244-255. doi: 10.1016/j.tig.2017.01.010. Epub 2017 Feb 27. Review.


The Importance of Context: Uncovering Species- and Tissue-Specific Effects of Genetic Risk Variants for Type 2 Diabetes.

Thomsen SK, McCarthy MI, Gloyn AL.

Front Endocrinol (Lausanne). 2016 Aug 31;7:112. doi: 10.3389/fendo.2016.00112. eCollection 2016. No abstract available.


Environmental contaminants and microRNA regulation: Transcription factors as regulators of toxicant-altered microRNA expression.

Sollome J, Martin E, Sethupathy P, Fry RC.

Toxicol Appl Pharmacol. 2016 Dec 1;312:61-66. doi: 10.1016/j.taap.2016.06.009. Epub 2016 Jun 10.


DNase I aggravates islet β-cell apoptosis in type 2 diabetes.

Zhu B, Zhang L, Zhang YY, Wang L, Li XG, Liu T, Fu YK, Zheng YF, Li P, Zhao ZG.

Mol Med Rep. 2016 Jun;13(6):4577-84. doi: 10.3892/mmr.2016.5102. Epub 2016 Apr 11.


Recent progress in genetic and epigenetic research on type 2 diabetes.

Kwak SH, Park KS.

Exp Mol Med. 2016 Mar 11;48:e220. doi: 10.1038/emm.2016.7. Review.


Epigenetic modifications and diabetic nephropathy.

Reddy MA, Park JT, Natarajan R.

Kidney Res Clin Pract. 2012 Sep;31(3):139-50. doi: 10.1016/j.krcp.2012.07.004. Epub 2012 Jul 21. Review.


Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.

Pujadas G, Cervantes S, Tutusaus A, Ejarque M, Sanchez L, García A, Esteban Y, Fargas L, Alsina B, Hartmann C, Gomis R, Gasa R.

Sci Rep. 2016 Jan 14;6:19223. doi: 10.1038/srep19223.


Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function.

Stitzel ML, Kycia I, Kursawe R, Ucar D.

Curr Diab Rep. 2015 Sep;15(9):66. doi: 10.1007/s11892-015-0635-0. Review.


Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis.

Vierra NC, Dadi PK, Jeong I, Dickerson M, Powell DR, Jacobson DA.

Diabetes. 2015 Nov;64(11):3818-28. doi: 10.2337/db15-0280. Epub 2015 Aug 3.


Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in β-Cells.

Soleimanpour SA, Ferrari AM, Raum JC, Groff DN, Yang J, Kaufman BA, Stoffers DA.

Diabetes. 2015 Oct;64(10):3475-84. doi: 10.2337/db15-0376. Epub 2015 Jun 17.


Epigenetic modifications and long noncoding RNAs influence pancreas development and function.

Arnes L, Sussel L.

Trends Genet. 2015 Jun;31(6):290-9. doi: 10.1016/j.tig.2015.02.008. Epub 2015 Mar 23. Review.


A systems view of epigenetic networks regulating pancreas development and β-cell function.

Xie R, Carrano AC, Sander M.

Wiley Interdiscip Rev Syst Biol Med. 2015 Jan-Feb;7(1):1-11. doi: 10.1002/wsbm.1287. Epub 2015 Jan 27. Review.


Enhancer variants: evaluating functions in common disease.

Corradin O, Scacheri PC.

Genome Med. 2014 Oct 28;6(10):85. doi: 10.1186/s13073-014-0085-3. eCollection 2014.


Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice.

Bailey KA, Savic D, Zielinski M, Park SY, Wang LJ, Witkowski P, Brady M, Hara M, Bell GI, Nobrega MA.

Hum Mol Genet. 2015 Mar 15;24(6):1646-54. doi: 10.1093/hmg/ddu577. Epub 2014 Nov 14.


Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.

Fogarty MP, Cannon ME, Vadlamudi S, Gaulton KJ, Mohlke KL.

PLoS Genet. 2014 Sep 11;10(9):e1004633. doi: 10.1371/journal.pgen.1004633. eCollection 2014 Sep.


Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.

Fadista J, Vikman P, Laakso EO, Mollet IG, Esguerra JL, Taneera J, Storm P, Osmark P, Ladenvall C, Prasad RB, Hansson KB, Finotello F, Uvebrant K, Ofori JK, Di Camillo B, Krus U, Cilio CM, Hansson O, Eliasson L, Rosengren AH, Renström E, Wollheim CB, Groop L.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13924-9. doi: 10.1073/pnas.1402665111. Epub 2014 Sep 8.


Profiling of embryonic stem cell differentiation.

Shiraki N, Ogaki S, Kume S.

Rev Diabet Stud. 2014 Spring;11(1):102-14. doi: 10.1900/RDS.2014.11.102. Epub 2014 May 10. Review.


Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans.

Esguerra JL, Eliasson L.

Front Genet. 2014 Jul 7;5:209. doi: 10.3389/fgene.2014.00209. eCollection 2014. Review.

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