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Items: 19


Upregulation of the long non-coding RNA PVT1 promotes esophageal squamous cell carcinoma progression by acting as a molecular sponge of miR-203 and LASP1.

Li PD, Hu JL, Ma C, Ma H, Yao J, Chen LL, Chen J, Cheng TT, Yang KY, Wu G, Zhang WJ, Cao RB.

Oncotarget. 2017 May 23;8(21):34164-34176. doi: 10.18632/oncotarget.15878.


Long non-coding RNA LINC00672 contributes to p53 protein-mediated gene suppression and promotes endometrial cancer chemosensitivity.

Li W, Li H, Zhang L, Hu M, Li F, Deng J, An M, Wu S, Ma R, Lu J, Zhou Y.

J Biol Chem. 2017 Apr 7;292(14):5801-5813. doi: 10.1074/jbc.M116.758508. Epub 2017 Feb 23.


Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1).

Endres M, Kneitz S, Orth MF, Perera RK, Zernecke A, Butt E.

Oncotarget. 2016 Sep 27;7(39):64244-64259. doi: 10.18632/oncotarget.11720.


LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression.

Vaman V S A, Poppe H, Houben R, Grunewald TG, Goebeler M, Butt E.

PLoS One. 2015 Jun 10;10(6):e0129219. doi: 10.1371/journal.pone.0129219. eCollection 2015.


Evolving transcriptomic fingerprint based on genome-wide data as prognostic tools in prostate cancer.

Alshalalfa M, Schliekelman M, Shin H, Erho N, Davicioni E.

Biol Cell. 2015 Jul;107(7):232-44. doi: 10.1111/boc.201400097. Epub 2015 Jun 16.


Molecular characterization of LASP-1 expression reveals vimentin as its new partner in human hepatocellular carcinoma cells.

Salvi A, Bongarzone I, Ferrari L, Abeni E, Arici B, De Bortoli M, Scuri S, Bonini D, Grossi I, Benetti A, Baiocchi G, Portolani N, De Petro G.

Int J Oncol. 2015 May;46(5):1901-12. doi: 10.3892/ijo.2015.2923. Epub 2015 Mar 9.


An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein.

Orth MF, Cazes A, Butt E, Grunewald TG.

Oncotarget. 2015 Jan 1;6(1):26-42. Review.


LASP1 is a HIF1α target gene critical for metastasis of pancreatic cancer.

Zhao T, Ren H, Li J, Chen J, Zhang H, Xin W, Sun Y, Sun L, Yang Y, Sun J, Wang X, Gao S, Huang C, Zhang H, Yang S, Hao J.

Cancer Res. 2015 Jan 1;75(1):111-9. doi: 10.1158/0008-5472.CAN-14-2040. Epub 2014 Nov 10.


Rewiring of an epithelial differentiation factor, miR-203, to inhibit human squamous cell carcinoma metastasis.

Benaich N, Woodhouse S, Goldie SJ, Mishra A, Quist SR, Watt FM.

Cell Rep. 2014 Oct 9;9(1):104-17. doi: 10.1016/j.celrep.2014.08.062. Epub 2014 Oct 2.


LIM and SH3 domain protein 1 (LASP-1) overexpression was associated with aggressive phenotype and poor prognosis in clear cell renal cell cancer.

Yang F, Zhou X, Du S, Zhao Y, Ren W, Deng Q, Wang F, Yuan J.

PLoS One. 2014 Jun 23;9(6):e100557. doi: 10.1371/journal.pone.0100557. eCollection 2014.


LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia.

Frietsch JJ, Kastner C, Grunewald TG, Schweigel H, Nollau P, Ziermann J, Clement JH, La Rosée P, Hochhaus A, Butt E.

Oncotarget. 2014 Jul 30;5(14):5257-71.


The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants.

Buss MC, Remke M, Lee J, Gandhi K, Schniederjan MJ, Kool M, Northcott PA, Pfister SM, Taylor MD, Castellino RC.

Oncogene. 2015 Feb 26;34(9):1126-40. doi: 10.1038/onc.2014.37. Epub 2014 Mar 17.


Overexpression of LIM and SH3 Protein 1 leading to accelerated G2/M phase transition contributes to enhanced tumourigenesis in oral cancer.

Shimizu F, Shiiba M, Ogawara K, Kimura R, Minakawa Y, Baba T, Yokota S, Nakashima D, Higo M, Kasamatsu A, Sakamoto Y, Tanzawa H, Uzawa K.

PLoS One. 2013 Dec 26;8(12):e83187. doi: 10.1371/journal.pone.0083187. eCollection 2013.


MicroRNA-203 suppresses cell proliferation and migration by targeting BIRC5 and LASP1 in human triple-negative breast cancer cells.

Wang C, Zheng X, Shen C, Shi Y.

J Exp Clin Cancer Res. 2012 Jun 19;31:58. doi: 10.1186/1756-9966-31-58.


WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.

Doucette TA, Yang Y, Pedone C, Kim JY, Dubuc A, Northcott PD, Taylor MD, Fults DW, Rao G.

Neurosurgery. 2012 Apr;70(4):1003-10; discussion 1010. doi: 10.1227/NEU.0b013e31823e5332.


Understanding tumor heterogeneity as functional compartments--superorganisms revisited.

Grunewald TG, Herbst SM, Heinze J, Burdach S.

J Transl Med. 2011 May 27;9:79. doi: 10.1186/1479-5876-9-79. Review.

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