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Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells.

Huang YH, Sun Y, Huang FY, Li YN, Wang CC, Mei WL, Dai HF, Tan GH, Huang C.

Oncotarget. 2017 Apr 18;8(32):52783-52791. doi: 10.18632/oncotarget.17189. eCollection 2017 Aug 8.


Blocking autophagy enhances the pro-apoptotic effect of bufalin on human gastric cancer cells through endoplasmic reticulum stress.

Zhao H, Li Q, Pang J, Jin H, Li H, Yang X.

Biol Open. 2017 Oct 15;6(10):1416-1422. doi: 10.1242/bio.026344.


Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy.

Yang Z, Su Z, DeWitt JP, Xie L, Chen Y, Li X, Han L, Li D, Xia J, Zhang Y, Yang Y, Jin C, Zhang J, Li S, Li K, Zhang Z, Qu X, He Z, Chen Y, Shen Y, Ren M, Yuan Z.

EBioMedicine. 2017 May;19:49-59. doi: 10.1016/j.ebiom.2017.04.017. Epub 2017 Apr 11.


Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth.

Li J, Liu J, Liang Z, He F, Yang L, Li P, Jiang Y, Wang B, Zhou C, Wang Y, Ren Y, Yang J, Zhang J, Luo Z, Vaziri C, Liu P.

Cell Death Dis. 2017 Mar 16;8(3):e2673. doi: 10.1038/cddis.2017.46.


The Different Effects of Atorvastatin and Pravastatin on Cell Death and PARP Activity in Pancreatic NIT-1 Cells.

Chen YH, Chen YC, Liu CS, Hsieh MC.

J Diabetes Res. 2016;2016:1828071. doi: 10.1155/2016/1828071. Epub 2016 Nov 27.


Chloroquine and hydroxychloroquine for cancer therapy.

Manic G, Obrist F, Kroemer G, Vitale I, Galluzzi L.

Mol Cell Oncol. 2014 Jul 15;1(1):e29911. doi: 10.4161/mco.29911. eCollection 2014. Review.


Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells.

Oh I, Cho H, Lee Y, Cheon M, Park D, Lee Y.

Dev Reprod. 2016 Mar;20(1):1-10. doi: 10.12717/DR.2016.20.1.001.


Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis.

Zhang J, Yi M, Zha L, Chen S, Li Z, Li C, Gong M, Deng H, Chu X, Chen J, Zhang Z, Mao L, Sun S.

PLoS One. 2016 Jan 19;11(1):e0147218. doi: 10.1371/journal.pone.0147218. eCollection 2016.


Silvestrol induces early autophagy and apoptosis in human melanoma cells.

Chen WL, Pan L, Kinghorn AD, Swanson SM, Burdette JE.

BMC Cancer. 2016 Jan 13;16:17. doi: 10.1186/s12885-015-1988-0.


Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy.

Miettinen TP, Björklund M.

Cell Rep. 2015 Dec 22;13(11):2610-2620. doi: 10.1016/j.celrep.2015.11.045. Epub 2015 Dec 10.


DMH1 (4-[6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline) inhibits chemotherapeutic drug-induced autophagy.

Sheng Y, Sun B, Xie X, Li N, Dong D.

Acta Pharm Sin B. 2015 Jul;5(4):330-6. doi: 10.1016/j.apsb.2014.12.010. Epub 2015 Feb 21.


Potential therapeutic effects of mTOR inhibition in atherosclerosis.

Kurdi A, De Meyer GR, Martinet W.

Br J Clin Pharmacol. 2016 Nov;82(5):1267-1279. doi: 10.1111/bcp.12820. Epub 2015 Dec 29. Review.


Neuroprotective Effect of Simvastatin via Inducing the Autophagy on Spinal Cord Injury in the Rat Model.

Gao K, Wang G, Wang Y, Han D, Bi J, Yuan Y, Yao T, Wan Z, Li H, Mei X.

Biomed Res Int. 2015;2015:260161. doi: 10.1155/2015/260161. Epub 2015 Oct 11.


Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury.

Chandrika BB, Yang C, Ou Y, Feng X, Muhoza D, Holmes AF, Theus S, Deshmukh S, Haun RS, Kaushal GP.

PLoS One. 2015 Oct 7;10(10):e0140025. doi: 10.1371/journal.pone.0140025. eCollection 2015.


The different roles of selective autophagic protein degradation in mammalian cells.

Wang DW, Peng ZJ, Ren GF, Wang GX.

Oncotarget. 2015 Nov 10;6(35):37098-116. doi: 10.18632/oncotarget.5776. Review.


Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells.

Hwang KE, Kim YS, Jung JW, Kwon SJ, Park DS, Cha BK, Oh SH, Yoon KH, Jeong ET, Kim HR.

Oncotarget. 2015 Oct 6;6(30):29482-96. doi: 10.18632/oncotarget.5022.


Autophagic regulation of cell growth by altered expression of Beclin 1 in triple-negative breast cancer.

Wang MC, Wu AG, Huang YZ, Shao GL, Ji SF, Wang RW, Yuan HJ, Fan XL, Zheng LH, Jiao QL.

Int J Clin Exp Med. 2015 May 15;8(5):7049-58. eCollection 2015.


Chemically induced mouse liver tumors are resistant to treatment with atorvastatin.

Braeuning A, Bucher P, Hofmann U, Buchmann A, Schwarz M.

BMC Cancer. 2014 Oct 15;14:766. doi: 10.1186/1471-2407-14-766.

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