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Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ.

Sameni M, Cavallo-Medved D, Franco OE, Chalasani A, Ji K, Aggarwal N, Anbalagan A, Chen X, Mattingly RR, Hayward SW, Sloane BF.

Breast Cancer Res. 2017 May 15;19(1):56. doi: 10.1186/s13058-017-0847-0.


ITIH5 mediates epigenetic reprogramming of breast cancer cells.

Rose M, Kloten V, Noetzel E, Gola L, Ehling J, Heide T, Meurer SK, Gaiko-Shcherbak A, Sechi AS, Huth S, Weiskirchen R, Klaas O, Antonopoulos W, Lin Q, Wagner W, Veeck J, Gremse F, Steitz J, Knüchel R, Dahl E.

Mol Cancer. 2017 Feb 23;16(1):44. doi: 10.1186/s12943-017-0610-2.


Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion.

Ahmadzadeh H, Webster MR, Behera R, Jimenez Valencia AM, Wirtz D, Weeraratna AT, Shenoy VB.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1617-E1626. doi: 10.1073/pnas.1617037114. Epub 2017 Feb 14.


3D Porous Chitosan-Alginate Scaffolds Promote Proliferation and Enrichment of Cancer Stem-Like Cells.

Florczyk SJ, Kievit FM, Wang K, Erickson AE, Ellenbogen RG, Zhang M.

J Mater Chem B Mater Biol Med. 2016 Oct 14;4(38):6326-6334. doi: 10.1039/C6TB01713D. Epub 2016 Aug 31.


3D bioprinting: improving in vitro models of metastasis with heterogeneous tumor microenvironments.

Albritton JL, Miller JS.

Dis Model Mech. 2017 Jan 1;10(1):3-14. doi: 10.1242/dmm.025049. Review.


A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties.

Clark AM, Wheeler SE, Young CL, Stockdale L, Shepard Neiman J, Zhao W, Stolz DB, Venkataramanan R, Lauffenburger D, Griffith L, Wells A.

Lab Chip. 2016 Dec 20;17(1):156-168.


Conserved Ankyrin Repeat Proteins and Their NIMA Kinase Partners Regulate Extracellular Matrix Remodeling and Intracellular Trafficking in Caenorhabditis elegans.

Lažetić V, Fay DS.

Genetics. 2017 Jan;205(1):273-293. doi: 10.1534/genetics.116.194464. Epub 2016 Oct 31.


Targeting extracellular matrix remodeling in disease: Could resveratrol be a potential candidate?

Agarwal R, Agarwal P.

Exp Biol Med (Maywood). 2017 Feb;242(4):374-383. doi: 10.1177/1535370216675065. Epub 2016 Oct 23.


Precise positioning of cancerous cells on PDMS substrates with gradients of elasticity.

Raczkowska J, Prauzner-Bechcicki S.

Biomed Microdevices. 2016 Oct;18(5):90. doi: 10.1007/s10544-016-0110-y.


ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion.

Chronopoulos A, Robinson B, Sarper M, Cortes E, Auernheimer V, Lachowski D, Attwood S, García R, Ghassemi S, Fabry B, Del Río Hernández A.

Nat Commun. 2016 Sep 7;7:12630. doi: 10.1038/ncomms12630.


Composite alginate gels for tunable cellular microenvironment mechanics.

Khavari A, Nydén M, Weitz DA, Ehrlicher AJ.

Sci Rep. 2016 Aug 3;6:30854. doi: 10.1038/srep30854.


Causes and consequences of nuclear envelope alterations in tumour progression.

Bell ES, Lammerding J.

Eur J Cell Biol. 2016 Nov;95(11):449-464. doi: 10.1016/j.ejcb.2016.06.007. Epub 2016 Jun 25. Review.


Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration.

Diz-Muñoz A, Thurley K, Chintamen S, Altschuler SJ, Wu LF, Fletcher DA, Weiner OD.

PLoS Biol. 2016 Jun 9;14(6):e1002474. doi: 10.1371/journal.pbio.1002474. eCollection 2016 Jun.


Mechanical cell competition kills cells via induction of lethal p53 levels.

Wagstaff L, Goschorska M, Kozyrska K, Duclos G, Kucinski I, Chessel A, Hampton-O'Neil L, Bradshaw CR, Allen GE, Rawlins EL, Silberzan P, Carazo Salas RE, Piddini E.

Nat Commun. 2016 Apr 25;7:11373. doi: 10.1038/ncomms11373.


Production of a Self-Aligned Scaffold, Free of Exogenous Material, from Dermal Fibroblasts Using the Self-Assembly Technique.

Chabaud S, Bolduc S.

Dermatol Res Pract. 2016;2016:5397319. doi: 10.1155/2016/5397319. Epub 2016 Mar 9.


Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha.

Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT.

Hepatology. 2016 Jul;64(1):261-75. doi: 10.1002/hep.28450. Epub 2016 Mar 9.


Mimicking biophysical stimuli within bone tumor microenvironment.

Marturano-Kruik A, Yeager K, Bach D, Villasante A, Cimetta E, Vunjak-Novakovic G.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3561-4. doi: 10.1109/EMBC.2015.7319162.


A synthetic modular approach for modeling the role of the 3D microenvironment in tumor progression.

Singh SP, Schwartz MP, Tokuda EY, Luo Y, Rogers RE, Fujita M, Ahn NG, Anseth KS.

Sci Rep. 2015 Dec 7;5:17814. doi: 10.1038/srep17814.


Magnetic resonance elastography (MRE) in cancer: Technique, analysis, and applications.

Pepin KM, Ehman RL, McGee KP.

Prog Nucl Magn Reson Spectrosc. 2015 Nov;90-91:32-48. doi: 10.1016/j.pnmrs.2015.06.001. Epub 2015 Jun 23. Review.


Forcing through Tumor Metastasis: The Interplay between Tissue Rigidity and Epithelial-Mesenchymal Transition.

Wei SC, Yang J.

Trends Cell Biol. 2016 Feb;26(2):111-20. doi: 10.1016/j.tcb.2015.09.009. Epub 2015 Oct 24. Review.

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