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Items: 1 to 20 of 93


Amitosis of Polyploid Cells Regenerates Functional Stem Cells in the Drosophila Intestine.

Lucchetta EM, Ohlstein B.

Cell Stem Cell. 2017 May 4;20(5):609-620.e6. doi: 10.1016/j.stem.2017.02.012. Epub 2017 Mar 23.


Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma.

Foijer F, Albacker LA, Bakker B, Spierings DC, Yue Y, Xie SZ, Davis S, Lutum-Jehle A, Takemoto D, Hare B, Furey B, Bronson RT, Lansdorp PM, Bradley A, Sorger PK.

Elife. 2017 Mar 20;6. pii: e20873. doi: 10.7554/eLife.20873.


p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging.

Tormos AM, Rius-Pérez S, Jorques M, Rada P, Ramirez L, Valverde ÁM, Nebreda ÁR, Sastre J, Taléns-Visconti R.

PLoS One. 2017 Feb 6;12(2):e0171738. doi: 10.1371/journal.pone.0171738. eCollection 2017.


TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells.

Pal D, Pertot A, Shirole NH, Yao Z, Anaparthy N, Garvin T, Cox H, Chang K, Rollins F, Kendall J, Edwards L, Singh VA, Stone GC, Schatz MC, Hicks J, Hannon GJ, Sordella R.

Elife. 2017 Jan 16;6. pii: e21615. doi: 10.7554/eLife.21615.


Modeling Dynamics and Function of Bone Marrow Cells in Mouse Liver Regeneration.

Pedone E, Olteanu VA, Marucci L, Muñoz-Martin MI, Youssef SA, de Bruin A, Cosma MP.

Cell Rep. 2017 Jan 3;18(1):107-121. doi: 10.1016/j.celrep.2016.12.008.


Linking genomic reorganization to tumor initiation via the giant cell cycle.

Niu N, Zhang J, Zhang N, Mercado-Uribe I, Tao F, Han Z, Pathak S, Multani AS, Kuang J, Yao J, Bast RC, Sood AK, Hung MC, Liu J.

Oncogenesis. 2016 Dec 19;5(12):e281. doi: 10.1038/oncsis.2016.75.


TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure.

De Santis Puzzonia M, Cozzolino AM, Grassi G, Bisceglia F, Strippoli R, Guarguaglini G, Citarella F, Sacchetti B, Tripodi M, Marchetti A, Amicone L.

PLoS One. 2016 Nov 28;11(11):e0167158. doi: 10.1371/journal.pone.0167158. eCollection 2016.


p53 on the crossroad between regeneration and cancer.

Charni M, Aloni-Grinstein R, Molchadsky A, Rotter V.

Cell Death Differ. 2017 Jan;24(1):8-14. doi: 10.1038/cdd.2016.117. Epub 2016 Oct 21. Review.


The Zn-finger domain of MdmX suppresses cancer progression by promoting genome stability in p53-mutant cells.

Matijasevic Z, Krzywicka-Racka A, Sluder G, Gallant J, Jones SN.

Oncogenesis. 2016 Oct 3;5(10):e262. doi: 10.1038/oncsis.2016.62.


Somatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signature.

Vazquez-Martin A, Anatskaya OV, Giuliani A, Erenpreisa J, Huang S, Salmina K, Inashkina I, Huna A, Nikolsky NN, Vinogradov AE.

Oncotarget. 2016 Nov 15;7(46):75235-75260. doi: 10.18632/oncotarget.12118.


Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice.

Vermeij WP, Dollé ME, Reiling E, Jaarsma D, Payan-Gomez C, Bombardieri CR, Wu H, Roks AJ, Botter SM, van der Eerden BC, Youssef SA, Kuiper RV, Nagarajah B, van Oostrom CT, Brandt RM, Barnhoorn S, Imholz S, Pennings JL, de Bruin A, Gyenis Á, Pothof J, Vijg J, van Steeg H, Hoeijmakers JH.

Nature. 2016 Sep 15;537(7620):427-431. doi: 10.1038/nature19329. Epub 2016 Aug 24.


Transient endoreplication down-regulates the kinesin-14 HSET and contributes to genomic instability.

Chen S, Stout JR, Dharmaiah S, Yde S, Calvi BR, Walczak CE.

Mol Biol Cell. 2016 Oct 1;27(19):2911-23. doi: 10.1091/mbc.E16-03-0159. Epub 2016 Aug 3.


Cell Fusion in the War on Cancer: A Perspective on the Inception of Malignancy.

Platt JL, Zhou X, Lefferts AR, Cascalho M.

Int J Mol Sci. 2016 Jul 13;17(7). pii: E1118. doi: 10.3390/ijms17071118. Review.


Wound-Induced Polyploidy Is Required for Tissue Repair.

Losick VP.

Adv Wound Care (New Rochelle). 2016 Jun 1;5(6):271-278. Review.


Essential role for a novel population of binucleated mammary epithelial cells in lactation.

Rios AC, Fu NY, Jamieson PR, Pal B, Whitehead L, Nicholas KR, Lindeman GJ, Visvader JE.

Nat Commun. 2016 Apr 22;7:11400. doi: 10.1038/ncomms11400.


Cellular plasticity in the adult liver and stomach.

Aloia L, McKie MA, Huch M.

J Physiol. 2016 Sep 1;594(17):4815-25. doi: 10.1113/JP271769. Epub 2016 May 10.


MicroRNA-122 regulates polyploidization in the murine liver.

Hsu SH, Delgado ER, Otero PA, Teng KY, Kutay H, Meehan KM, Moroney JB, Monga JK, Hand NJ, Friedman JR, Ghoshal K, Duncan AW.

Hepatology. 2016 Aug;64(2):599-615. doi: 10.1002/hep.28573. Epub 2016 May 12.


Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals.

Losick VP, Jun AS, Spradling AC.

PLoS One. 2016 Mar 9;11(3):e0151251. doi: 10.1371/journal.pone.0151251. eCollection 2016.


Selective advantage of trisomic human cells cultured in non-standard conditions.

Rutledge SD, Douglas TA, Nicholson JM, Vila-Casadesús M, Kantzler CL, Wangsa D, Barroso-Vilares M, Kale SD, Logarinho E, Cimini D.

Sci Rep. 2016 Mar 9;6:22828. doi: 10.1038/srep22828.

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