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Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes.

Phares TW, May AD, Genito CJ, Hoyt NA, Khan FA, Porter MD, DeBot M, Waters NC, Saudan P, Dutta S.

Malar J. 2017 Mar 13;16(1):115. doi: 10.1186/s12936-017-1766-3.


Dendritic Cell Targeting Effectively Boosts T Cell Responses Elicited by an HIV Multiepitope DNA Vaccine.

Apostólico JS, Lunardelli VA, Yamamoto MM, Souza HF, Cunha-Neto E, Boscardin SB, Rosa DS.

Front Immunol. 2017 Feb 7;8:101. doi: 10.3389/fimmu.2017.00101. eCollection 2017.


The presence of T cell epitopes is important for induction of antibody responses against antigens directed to DEC205+ dendritic cells.

Amorim KN, Rampazo EV, Antonialli R, Yamamoto MM, Rodrigues MM, Soares IS, Boscardin SB.

Sci Rep. 2016 Dec 21;6:39250. doi: 10.1038/srep39250.


PolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In Vivo.

Aravantinou M, Frank I, Hallor M, Singer R, Tharinger H, Kenney J, Gettie A, Grasperge B, Blanchard J, Salazar A, Piatak M Jr, Lifson JD, Robbiani M, Derby N.

PLoS One. 2016 Sep 7;11(9):e0161730. doi: 10.1371/journal.pone.0161730. eCollection 2016.


Adjuvants: Classification, Modus Operandi, and Licensing.

Apostólico Jde S, Lunardelli VA, Coirada FC, Boscardin SB, Rosa DS.

J Immunol Res. 2016;2016:1459394. doi: 10.1155/2016/1459394. Epub 2016 May 4. Review.


Dendritic Cells and Their Multiple Roles during Malaria Infection.

Amorim KN, Chagas DC, Sulczewski FB, Boscardin SB.

J Immunol Res. 2016;2016:2926436. doi: 10.1155/2016/2926436. Epub 2016 Mar 24. Review.


Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques.

Zurawski G, Zurawski S, Flamar AL, Richert L, Wagner R, Tomaras GD, Montefiori DC, Roederer M, Ferrari G, Lacabaratz C, Bonnabau H, Klucar P, Wang Z, Foulds KE, Kao SF, Yates NL, LaBranche C, Jacobs BL, Kibler K, Asbach B, Kliche A, Salazar A, Reed S, Self S, Gottardo R, Galmin L, Weiss D, Cristillo A, Thiebaut R, Pantaleo G, Levy Y.

PLoS One. 2016 Apr 14;11(4):e0153484. doi: 10.1371/journal.pone.0153484. eCollection 2016.


Systemic Activation of TLR3-Dependent TRIF Signaling Confers Host Defense against Gram-Negative Bacteria in the Intestine.

Ruiz J, Kanagavelu S, Flores C, Romero L, Riveron R, Shih DQ, Fukata M.

Front Cell Infect Microbiol. 2016 Jan 12;5:105. doi: 10.3389/fcimb.2015.00105. eCollection 2015.


Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo.

Flamar AL, Contreras V, Zurawski S, Montes M, Dereuddre-Bosquet N, Martinon F, Banchereau J, Le Grand R, Zurawski G, Levy Y.

PLoS One. 2015 Sep 25;10(9):e0135513. doi: 10.1371/journal.pone.0135513. eCollection 2015.


Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.

Hanson MC, Crespo MP, Abraham W, Moynihan KD, Szeto GL, Chen SH, Melo MB, Mueller S, Irvine DJ.

J Clin Invest. 2015 Jun;125(6):2532-46. doi: 10.1172/JCI79915. Epub 2015 May 4.


Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells.

Balan S, Ollion V, Colletti N, Chelbi R, Montanana-Sanchis F, Liu H, Vu Manh TP, Sanchez C, Savoret J, Perrot I, Doffin AC, Fossum E, Bechlian D, Chabannon C, Bogen B, Asselin-Paturel C, Shaw M, Soos T, Caux C, Valladeau-Guilemond J, Dalod M.

J Immunol. 2014 Aug 15;193(4):1622-35. doi: 10.4049/jimmunol.1401243. Epub 2014 Jul 9.


Dendritic cell-targeted vaccines.

Cohn L, Delamarre L.

Front Immunol. 2014 May 30;5:255. doi: 10.3389/fimmu.2014.00255. eCollection 2014. Review.


Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation.

Martins KA, Steffens JT, van Tongeren SA, Wells JB, Bergeron AA, Dickson SP, Dye JM, Salazar AM, Bavari S.

PLoS One. 2014 Feb 24;9(2):e89735. doi: 10.1371/journal.pone.0089735. eCollection 2014.


Resiquimod and polyinosinic-polycytidylic acid formulation with aluminum hydroxide as an adjuvant for foot-and-mouth disease vaccine.

Zhou CX, Li D, Chen YL, Lu ZJ, Sun P, Cao YM, Bao HF, Fu YF, Li PH, Bai XW, Xie BX, Liu ZX.

BMC Vet Res. 2014 Jan 3;10:2. doi: 10.1186/1746-6148-10-2.


Liposome-antigen-nucleic acid complexes protect mice from lethal challenge with western and eastern equine encephalitis viruses.

Phillips AT, Schountz T, Toth AM, Rico AB, Jarvis DL, Powers AM, Olson KE.

J Virol. 2014 Feb;88(3):1771-80. doi: 10.1128/JVI.02297-13. Epub 2013 Nov 20.


Highly immunostimulatory RNA derived from a Sendai virus defective viral genome.

Mercado-López X, Cotter CR, Kim WK, Sun Y, Muñoz L, Tapia K, López CB.

Vaccine. 2013 Nov 19;31(48):5713-21. doi: 10.1016/j.vaccine.2013.09.040. Epub 2013 Oct 5.


Coadministration of polyinosinic:polycytidylic acid and immunostimulatory complexes modifies antigen processing in dendritic cell subsets and enhances HIV gag-specific T cell immunity.

Quinn KM, Yamamoto A, Costa A, Darrah PA, Lindsay RW, Hegde ST, Johnson TR, Flynn BJ, Loré K, Seder RA.

J Immunol. 2013 Nov 15;191(10):5085-96. doi: 10.4049/jimmunol.1301730. Epub 2013 Oct 2.


Chemical cross-linking of HIV-1 Env for direct TLR7/8 ligand conjugation compromises recognition of conserved antigenic determinants.

Feng Y, Forsell MN, Flynn B, Adams W, Loré K, Seder R, Wyatt RT, Karlsson Hedestam GB.

Virology. 2013 Nov;446(1-2):56-65. doi: 10.1016/j.virol.2013.07.028. Epub 2013 Aug 15.


Sweeten PAMPs: Role of Sugar Complexed PAMPs in Innate Immunity and Vaccine Biology.

Mahla RS, Reddy MC, Prasad DV, Kumar H.

Front Immunol. 2013 Sep 2;4:248. doi: 10.3389/fimmu.2013.00248. Review.

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