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Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA.

Iyer DR, Rhind N.

PLoS Genet. 2017 Aug 14;13(8):e1006958. doi: 10.1371/journal.pgen.1006958. eCollection 2017 Aug.


Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition.

Collart C, Smith JC, Zegerman P.

Dev Cell. 2017 Jul 10;42(1):82-96.e3. doi: 10.1016/j.devcel.2017.06.010.


A novel p53-Cdc7 link induced by genotoxic stress.

Masai H.

Cell Cycle. 2017 Apr 18;16(8):735-736. doi: 10.1080/15384101.2017.1304746. Epub 2017 Mar 15. No abstract available.


S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion.

Giannattasio M, Branzei D.

Cell Mol Life Sci. 2017 Jul;74(13):2361-2380. doi: 10.1007/s00018-017-2474-4. Epub 2017 Feb 20. Review.


The Intra-S Checkpoint Responses to DNA Damage.

Iyer DR, Rhind N.

Genes (Basel). 2017 Feb 17;8(2). pii: E74. doi: 10.3390/genes8020074. Review.


Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosis.

Princz LN, Wild P, Bittmann J, Aguado FJ, Blanco MG, Matos J, Pfander B.

EMBO J. 2017 Mar 1;36(5):664-678. doi: 10.15252/embj.201694831. Epub 2017 Jan 17.


Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection.

Bantele SC, Ferreira P, Gritenaite D, Boos D, Pfander B.

Elife. 2017 Jan 12;6. pii: e21687. doi: 10.7554/eLife.21687.


Mec1/ATR, the Program Manager of Nucleic Acids Inc.

Feng W.

Genes (Basel). 2016 Dec 28;8(1). pii: E10. doi: 10.3390/genes8010010. Review.


Mechanisms Governing DDK Regulation of the Initiation of DNA Replication.

Larasati, Duncker BP.

Genes (Basel). 2016 Dec 22;8(1). pii: E3. doi: 10.3390/genes8010003. Review.


The Cell Killing Mechanisms of Hydroxyurea.

Singh A, Xu YJ.

Genes (Basel). 2016 Nov 17;7(11). pii: E99. Review.


Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication.

Shyian M, Mattarocci S, Albert B, Hafner L, Lezaja A, Costanzo M, Boone C, Shore D.

PLoS Genet. 2016 Nov 7;12(11):e1006414. doi: 10.1371/journal.pgen.1006414. eCollection 2016 Nov.


'AND' logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7.

Almawi AW, Matthews LA, Larasati, Myrox P, Boulton S, Lai C, Moraes T, Melacini G, Ghirlando R, Duncker BP, Guarné A.

Sci Rep. 2016 Sep 29;6:34237. doi: 10.1038/srep34237.


Prevention of DNA Rereplication Through a Meiotic Recombination Checkpoint Response.

Najor NA, Weatherford L, Brush GS.

G3 (Bethesda). 2016 Dec 7;6(12):3869-3881. doi: 10.1534/g3.116.033910.


Candida albicans Dbf4-dependent Cdc7 kinase plays a novel role in the inhibition of hyphal development.

Lai WC, Chang TW, Wu CH, Yang SY, Lee TL, Li WC, Chien T, Cheng YC, Shieh JC.

Sci Rep. 2016 Sep 20;6:33716. doi: 10.1038/srep33716.


Hydroxyurea Induces Cytokinesis Arrest in Cells Expressing a Mutated Sterol-14α-Demethylase in the Ergosterol Biosynthesis Pathway.

Xu YJ, Singh A, Alter GM.

Genetics. 2016 Nov;204(3):959-973. doi: 10.1534/genetics.116.191536. Epub 2016 Aug 31.


Chromosome Duplication in Saccharomyces cerevisiae.

Bell SP, Labib K.

Genetics. 2016 Jul;203(3):1027-67. doi: 10.1534/genetics.115.186452. Review.


Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation.

Deegan TD, Yeeles JT, Diffley JF.

EMBO J. 2016 May 2;35(9):961-73. doi: 10.15252/embj.201593552. Epub 2016 Feb 24.


A new MCM modification cycle regulates DNA replication initiation.

Wei L, Zhao X.

Nat Struct Mol Biol. 2016 Mar;23(3):209-16. doi: 10.1038/nsmb.3173. Epub 2016 Feb 8.


The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress.

Buser R, Kellner V, Melnik A, Wilson-Zbinden C, Schellhaas R, Kastner L, Piwko W, Dees M, Picotti P, Maric M, Labib K, Luke B, Peter M.

PLoS Genet. 2016 Feb 5;12(2):e1005843. doi: 10.1371/journal.pgen.1005843. eCollection 2016 Feb.


Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress.

Simoneau A, Ricard É, Weber S, Hammond-Martel I, Wong LH, Sellam A, Giaever G, Nislow C, Raymond M, Wurtele H.

Nucleic Acids Res. 2016 Apr 7;44(6):2706-26. doi: 10.1093/nar/gkv1537. Epub 2016 Jan 8.

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