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Items: 1 to 20 of 175


Neutron Crystallography Detects Differences in Protein Dynamics: Structure of the PKG II Cyclic Nucleotide Binding Domain in Complex with an Activator.

Gerlits O, Campbell JC, Blakeley MP, Kim C, Kovalevsky A.

Biochemistry. 2018 Mar 27;57(12):1833-1837. doi: 10.1021/acs.biochem.8b00010. Epub 2018 Mar 13.


Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension.

Gheibi S, Jeddi S, Kashfi K, Ghasemi A.

Biochem Pharmacol. 2018 Mar;149:42-59. doi: 10.1016/j.bcp.2018.01.017. Epub 2018 Jan 9. Review.


Cyclic-GMP-Elevating Agents Suppress Polyposis in ApcMin mice by Targeting the Preneoplastic Epithelium.

Sharman SK, Islam BN, Hou Y, Singh N, Berger FG, Sridhar S, Yoo W, Browning DD.

Cancer Prev Res (Phila). 2018 Feb;11(2):81-92. doi: 10.1158/1940-6207.CAPR-17-0267. Epub 2018 Jan 4.


The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis.

Flores-Costa R, Alcaraz-Quiles J, Titos E, López-Vicario C, Casulleras M, Duran-Güell M, Rius B, Diaz A, Hall K, Shea C, Sarno R, Currie M, Masferrer JL, Clària J.

Br J Pharmacol. 2018 Mar;175(6):953-967. doi: 10.1111/bph.14137. Epub 2018 Jan 31.


Cyclic nucleotide signalling in malaria parasites.

Baker DA, Drought LG, Flueck C, Nofal SD, Patel A, Penzo M, Walker EM.

Open Biol. 2017 Dec;7(12). pii: 170213. doi: 10.1098/rsob.170213. Review.


Phosphodiesterase type 5 and cancers: progress and challenges.

Barone I, Giordano C, Bonofiglio D, Andò S, Catalano S.

Oncotarget. 2017 Oct 12;8(58):99179-99202. doi: 10.18632/oncotarget.21837. eCollection 2017 Nov 17. Review.


Antihypertensive Effects of Roselle-Olive Combination in L-NAME-Induced Hypertensive Rats.

Abdel-Rahman RF, Hessin AF, Abdelbaset M, Ogaly HA, Abd-Elsalam RM, Hassan SM.

Oxid Med Cell Longev. 2017;2017:9460653. doi: 10.1155/2017/9460653. Epub 2017 Oct 22.


Switching Cyclic Nucleotide-Selective Activation of Cyclic Adenosine Monophosphate-Dependent Protein Kinase Holoenzyme Reveals Distinct Roles of Tandem Cyclic Nucleotide-Binding Domains.

He D, Lorenz R, Kim C, Herberg FW, Lim CJ.

ACS Chem Biol. 2017 Dec 15;12(12):3057-3066. doi: 10.1021/acschembio.7b00732. Epub 2017 Nov 21.


Identification of dual mechanisms mediating 5-hydroxytryptamine receptor 1F-induced mitochondrial biogenesis.

Gibbs WS, Garrett SM, Beeson CC, Schnellmann RG.

Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F260-F268. doi: 10.1152/ajprenal.00324.2017. Epub 2017 Oct 18.


NO-sGC Pathway Modulates Ca2+ Release and Muscle Contraction in Zebrafish Skeletal Muscle.

Xiyuan Z, Fink RHA, Mosqueira M.

Front Physiol. 2017 Aug 23;8:607. doi: 10.3389/fphys.2017.00607. eCollection 2017.


Structural Basis of Analog Specificity in PKG I and II.

Campbell JC, Henning P, Franz E, Sankaran B, Herberg FW, Kim C.

ACS Chem Biol. 2017 Sep 15;12(9):2388-2398. doi: 10.1021/acschembio.7b00369. Epub 2017 Aug 22.


Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1α and Repression of NF-κB.

Braverman J, Stanley SA.

J Immunol. 2017 Sep 1;199(5):1805-1816. doi: 10.4049/jimmunol.1700515. Epub 2017 Jul 28.


Loss of nitric oxide-mediated inhibition of purine neurotransmitter release in the colon in the absence of interstitial cells of Cajal.

Durnin L, Lees A, Manzoor S, Sasse KC, Sanders KM, Mutafova-Yambolieva VN.

Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G419-G433. doi: 10.1152/ajpgi.00045.2017. Epub 2017 Jul 13.


Examining a role for PKG Iα oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity.

Rudyk O, Eaton P.

Free Radic Biol Med. 2017 Sep;110:390-398. doi: 10.1016/j.freeradbiomed.2017.07.007. Epub 2017 Jul 6.


Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming.

D'Alessandro A, El Kasmi KC, Plecitá-Hlavatá L, Ježek P, Li M, Zhang H, Gupte SA, Stenmark KR.

Antioxid Redox Signal. 2018 Jan 20;28(3):230-250. doi: 10.1089/ars.2017.7217. Epub 2017 Aug 14.


Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone.

Podewin T, Broichhagen J, Frost C, Groneberg D, Ast J, Meyer-Berg H, Fine NHF, Friebe A, Zacharias M, Hodson DJ, Trauner D, Hoffmann-Röder A.

Chem Sci. 2017 Jun 1;8(6):4644-4653. doi: 10.1039/c6sc05044a. Epub 2017 Apr 19.


Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.

Lorenz R, Moon EW, Kim JJ, Schmidt SH, Sankaran B, Pavlidis IV, Kim C, Herberg FW.

Biochem J. 2017 Jul 6;474(14):2389-2403. doi: 10.1042/BCJ20160969.


GluA2-Lacking AMPA Receptors and Nitric Oxide Signaling Gate Spike-Timing-Dependent Potentiation of Glutamate Synapses in the Dorsal Raphe Nucleus.

Haj-Dahmane S, Béïque JC, Shen RY.

eNeuro. 2017 Jun 2;4(3). pii: ENEURO.0116-17.2017. doi: 10.1523/ENEURO.0116-17.2017. eCollection 2017 May-Jun.


Assessment of endothelial cell function and physiological microcirculatory reserve by video microscopy using a topical acetylcholine and nitroglycerin challenge.

Hilty MP, Pichler J, Ergin B, Hefti U, Merz TM, Ince C, Maggiorini M.

Intensive Care Med Exp. 2017 Dec;5(1):26. doi: 10.1186/s40635-017-0139-0. Epub 2017 May 18.


Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease.

Mullins RJ, Diehl TC, Chia CW, Kapogiannis D.

Front Aging Neurosci. 2017 May 3;9:118. doi: 10.3389/fnagi.2017.00118. eCollection 2017.

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