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Items: 1 to 20 of 902

1.

The genetic and epigenetic landscapes of the epithelium in asthma.

Moheimani F, Hsu AC, Reid AT, Williams T, Kicic A, Stick SM, Hansbro PM, Wark PA, Knight DA.

Respir Res. 2016 Sep 22;17(1):119. Review.

2.
3.

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S, Kleber ME, Guo X, Lyytikäinen LP, Fava C, Eriksson N, Nolte IM, Magnusson PK, Salfati EL, Rallidis LS, Theusch E, Smith AJ, Folkersen L, Witkowska K, Pers TH, Joehanes R, Kim SK, Lataniotis L, Jansen R, Johnson AD, Warren H, Kim YJ, Zhao W, Wu Y, Tayo BO, Bochud M; CHARGE-EchoGen Consortium; CHARGE-HF Consortium; Wellcome Trust Case Control Consortium, Absher D, Adair LS, Amin N, Arking DE, Axelsson T, Baldassarre D, Balkau B, Bandinelli S, Barnes MR, Barroso I, Bevan S, Bis JC, Bjornsdottir G, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Bornstein SR, Brown MJ, Burnier M, Cabrera CP, Chambers JC, Chang IS, Cheng CY, Chines PS, Chung RH, Collins FS, Connell JM, Döring A, Dallongeville J, Danesh J, de Faire U, Delgado G, Dominiczak AF, Doney AS, Drenos F, Edkins S, Eicher JD, Elosua R, Enroth S, Erdmann J, Eriksson P, Esko T, Evangelou E, Evans A, Fall T, Farrall M, Felix JF, Ferrières J, Ferrucci L, Fornage M, Forrester T, Franceschini N, Franco OH, Franco-Cereceda A, Fraser RM, Ganesh SK, Gao H, Gertow K, Gianfagna F, Gigante B, Giulianini F, Goel A, Goodall AH, Goodarzi MO, Gorski M, Gräßler J, Groves CJ, Gudnason V, Gyllensten U, Hallmans G, Hartikainen AL, Hassinen M, Havulinna AS, Hayward C, Hercberg S, Herzig KH, Hicks AA, Hingorani AD, Hirschhorn JN, Hofman A, Holmen J, Holmen OL, Hottenga JJ, Howard P, Hsiung CA, Hunt SC, Ikram MA, Illig T, Iribarren C, Jensen RA, Kähönen M, Kang HM, Kathiresan S, Keating BJ, Khaw KT, Kim YK, Kim E, Kivimaki M, Klopp N, Kolovou G, Komulainen P, Kooner JS, Kosova G, Krauss RM, Kuh D, Kutalik Z, Kuusisto J, Kvaløy K, Lakka TA, Lee NR, Lee IT, Lee WJ, Levy D, Li X, Liang KW, Lin H, Lin L, Lindström J, Lobbens S, Männistö S, Müller G, Müller-Nurasyid M, Mach F, Markus HS, Marouli E, McCarthy MI, McKenzie CA, Meneton P, Menni C, Metspalu A, Mijatovic V, Moilanen L, Montasser ME, Morris AD, Morrison AC, Mulas A, Nagaraja R, Narisu N, Nikus K, O'Donnell CJ, O'Reilly PF, Ong KK, Paccaud F, Palmer CD, Parsa A, Pedersen NL, Penninx BW, Perola M, Peters A, Poulter N, Pramstaller PP, Psaty BM, Quertermous T, Rao DC, Rasheed A, Rayner NW, Renström F, Rettig R, Rice KM, Roberts R, Rose LM, Rossouw J, Samani NJ, Sanna S, Saramies J, Schunkert H, Sebert S, Sheu WH, Shin YA, Sim X, Smit JH, Smith AV, Sosa MX, Spector TD, Stančáková A, Stanton AV, Stirrups KE, Stringham HM, Sundstrom J, Swift AJ, Syvänen AC, Tai ES, Tanaka T, Tarasov KV, Teumer A, Thorsteinsdottir U, Tobin MD, Tremoli E, Uitterlinden AG, Uusitupa M, Vaez A, Vaidya D, van Duijn CM, van Iperen EP, Vasan RS, Verwoert GC, Virtamo J, Vitart V, Voight BF, Vollenweider P, Wagner A, Wain LV, Wareham NJ, Watkins H, Weder AB, Westra HJ, Wilks R, Wilsgaard T, Wilson JF, Wong TY, Yang TP, Yao J, Yengo L, Zhang W, Zhao JH, Zhu X, Bovet P, Cooper RS, Mohlke KL, Saleheen D, Lee JY, Elliott P, Gierman HJ, Willer CJ, Franke L, Hovingh GK, Taylor KD, Dedoussis G, Sever P, Wong A, Lind L, Assimes TL, Njølstad I, Schwarz PE, Langenberg C, Snieder H, Caulfield MJ, Melander O, Laakso M, Saltevo J, Rauramaa R, Tuomilehto J, Ingelsson E, Lehtimäki T, Hveem K, Palmas W, März W, Kumari M, Salomaa V, Chen YD, Rotter JI, Froguel P, Jarvelin MR, Lakatta EG, Kuulasmaa K, Franks PW, Hamsten A, Wichmann HE, Palmer CN, Stefansson K, Ridker PM, Loos RJ, Chakravarti A, Deloukas P, Morris AP, Newton-Cheh C, Munroe PB.

Nat Genet. 2016 Oct;48(10):1171-84. doi: 10.1038/ng.3667. Epub 2016 Sep 12.

PMID:
27618452
4.

Complex interplay between neutral and adaptive evolution shaped differential genomic background and disease susceptibility along the Italian peninsula.

Sazzini M, Gnecchi Ruscone GA, Giuliani C, Sarno S, Quagliariello A, De Fanti S, Boattini A, Gentilini D, Fiorito G, Catanoso M, Boiardi L, Croci S, Macchioni P, Mantovani V, Di Blasio AM, Matullo G, Salvarani C, Franceschi C, Pettener D, Garagnani P, Luiselli D.

Sci Rep. 2016 Sep 1;6:32513. doi: 10.1038/srep32513.

5.

Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes.

Mallanna SK, Cayo MA, Twaroski K, Gundry RL, Duncan SA.

Stem Cell Reports. 2016 Sep 13;7(3):543-56. doi: 10.1016/j.stemcr.2016.07.016. Epub 2016 Aug 25.

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7.

Genetic susceptibility to dyslipidemia and incidence of cardiovascular disease depending on a diet quality index in the Malmö Diet and Cancer cohort.

Hellstrand S, Ericson U, Schulz CA, Drake I, Gullberg B, Hedblad B, Engström G, Orho-Melander M, Sonestedt E.

Genes Nutr. 2016 Jul 7;11:20. doi: 10.1186/s12263-016-0536-0. eCollection 2016.

8.

Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids.

Beaney KE, Cooper JA, McLachlan S, Wannamethee SG, Jefferis BJ, Whincup P, Ben-Shlomo Y, Price JF, Kumari M, Wong A, Ong K, Hardy R, Kuh D, Kivimaki M, Kangas AJ, Soininen P, Ala-Korpela M, Drenos F, Humphries SE; UCLEB consortium.

Cardiovasc Diabetol. 2016 Aug 22;15(1):115. doi: 10.1186/s12933-016-0435-0.

9.

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.

Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, Cho MH, Comellas A, Crapo JD, Criner G, Demeo D, Christenson SA, Couper DJ, Curtis JL, Doerschuk CM, Freeman CM, Gouskova NA, Han MK, Hanania NA, Hansel NN, Hersh CP, Hoffman EA, Kaner RJ, Kanner RE, Kleerup EC, Lutz S, Martinez FJ, Meyers DA, Peters SP, Regan EA, Rennard SI, Scholand MB, Silverman EK, Woodruff PG, O'Neal WK, Bowler RP; SPIROMICS Research Group; COPDGene Investigators.

PLoS Genet. 2016 Aug 17;12(8):e1006011. doi: 10.1371/journal.pgen.1006011. eCollection 2016 Aug.

10.

Methylation quantitative trait loci within the TOMM20 gene are associated with metabolic syndrome-related lipid alterations in severely obese subjects.

de Toro-Martín J, Guénard F, Tchernof A, Deshaies Y, Pérusse L, Hould FS, Lebel S, Marceau P, Vohl MC.

Diabetol Metab Syndr. 2016 Jul 29;8:55. doi: 10.1186/s13098-016-0171-3. eCollection 2016.

11.

SILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics - Resveratrol as Ameliorating Factor on LPS Induced Changes.

Nøhr MK, Kroager TP, Sanggaard KW, Knudsen AD, Stensballe A, Enghild JJ, Ølholm J, Richelsen B, Pedersen SB.

PLoS One. 2016 Jul 20;11(7):e0159747. doi: 10.1371/journal.pone.0159747. eCollection 2016.

12.

APOE polymorphisms influence longitudinal lipid trends preceding intracerebral hemorrhage.

Phuah CL, Raffeld MR, Ayres AM, Gurol ME, Viswanathan A, Greenberg SM, Biffi A, Rosand J, Anderson CD.

Neurol Genet. 2016 Jun 23;2(4):e81. doi: 10.1212/NXG.0000000000000081. eCollection 2016 Aug.

13.

Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study.

Peloso GM, Lange LA, Varga TV, Nickerson DA, Smith JD, Griswold ME, Musani S, Polfus LM, Mei H, Gabriel S, Quarells RC, Altshuler D, Boerwinkle E, Daly MJ, Neale B, Correa A, Reiner AP, Wilson JG, Kathiresan S.

Circ Cardiovasc Genet. 2016 Aug;9(4):368-74. doi: 10.1161/CIRCGENETICS.116.001410. Epub 2016 Jul 15.

PMID:
27422940
14.

Multidimensional regulation of lipoprotein lipase: impact on biochemical and cardiovascular phenotypes.

Hegele RA.

J Lipid Res. 2016 Sep;57(9):1601-7. doi: 10.1194/jlr.C070946. Epub 2016 Jul 13. No abstract available.

PMID:
27412676
15.

Genetic evidence for natural selection in humans in the contemporary United States.

Beauchamp JP.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7774-9. doi: 10.1073/pnas.1600398113. Epub 2016 Jul 11.

PMID:
27402742
16.

TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.

Hsieh J, Koseki M, Molusky MM, Yakushiji E, Ichi I, Westerterp M, Iqbal J, Chan RB, Abramowicz S, Tascau L, Takiguchi S, Yamashita S, Welch CL, Di Paolo G, Hussain MM, Lefkowitch JH, Rader DJ, Tall AR.

Nature. 2016 Jul 6;535(7611):303-7. doi: 10.1038/nature18628.

PMID:
27383786
17.

Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.

Ligthart S, Vaez A, Hsu YH; Inflammation Working Group of the CHARGE Consortium; PMI-WG-XCP; LifeLines Cohort Study, Stolk R, Uitterlinden AG, Hofman A, Alizadeh BZ, Franco OH, Dehghan A.

BMC Genomics. 2016 Jun 10;17:443. doi: 10.1186/s12864-016-2712-4.

18.

Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans.

McLachlan S, Giambartolomei C, White J, Charoen P, Wong A, Finan C, Engmann J, Shah T, Hersch M, Podmore C, Cavadino A, Jefferis BJ, Dale CE, Hypponen E, Morris RW, Casas JP, Kumari M, Ben-Shlomo Y, Gaunt TR, Drenos F, Langenberg C, Kuh D, Kivimaki M, Rueedi R, Waeber G, Hingorani AD, Price JF, Walker AP; UCLEB Consortium.

PLoS One. 2016 Jun 9;11(6):e0156914. doi: 10.1371/journal.pone.0156914. eCollection 2016.

19.
20.

The Contribution of GWAS Loci in Familial Dyslipidemias.

Ripatti P, Rämö JT, Söderlund S, Surakka I, Matikainen N, Pirinen M, Pajukanta P, Sarin AP, Service SK, Laurila PP, Ehnholm C, Salomaa V, Wilson RK, Palotie A, Freimer NB, Taskinen MR, Ripatti S.

PLoS Genet. 2016 May 26;12(5):e1006078. doi: 10.1371/journal.pgen.1006078. eCollection 2016 May.

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