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Correlation between TSC1 gene polymorphism and epilepsy.

Jiang X, Chen J, Song Q, Wang W, Zhang G, Li Y.

Exp Ther Med. 2017 Dec;14(6):6238-6242. doi: 10.3892/etm.2017.5345. Epub 2017 Oct 19.


Developmental Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether Induces Long-Lasting Changes in Liver Metabolism in Male Mice.

Khalil A, Parker M, Mpanga R, Cevik SE, Thorburn C, Suvorov A.

J Endocr Soc. 2017 Mar 14;1(4):323-344. doi: 10.1210/js.2016-1011. eCollection 2017 Apr 1.


UCP2 overexpression enhanced glycolysis via activation of PFKFB2 during skin cell transformation.

Sreedhar A, Petruska P, Miriyala S, Panchatcharam M, Zhao Y.

Oncotarget. 2017 Sep 8;8(56):95504-95515. doi: 10.18632/oncotarget.20762. eCollection 2017 Nov 10.


Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control.

Mah AY, Rashidi A, Keppel MP, Saucier N, Moore EK, Alinger JB, Tripathy SK, Agarwal SK, Jeng EK, Wong HC, Miller JS, Fehniger TA, Mace EM, French AR, Cooper MA.

JCI Insight. 2017 Dec 7;2(23). pii: 95128. doi: 10.1172/jci.insight.95128. [Epub ahead of print]


Imaging Cancer Metabolism.

Momcilovic M, Shackelford DB.

Biomol Ther (Seoul). 2018 Jan 1;26(1):81-92. doi: 10.4062/biomolther.2017.220. Review.


AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts.

Sanchez-Alvarez M, Del Pozo MA, Bakal C.

Sci Rep. 2017 Nov 28;7(1):16497. doi: 10.1038/s41598-017-16662-1.


mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci.

Kelsey I, Zbinden M, Byles V, Torrence M, Manning BD.

Sci Rep. 2017 Nov 23;7(1):16112. doi: 10.1038/s41598-017-16398-y.


Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis.

Qi M, Zhang L, Ma Y, Shuai Y, Li L, Luo K, Liu W, Jin Y.

Theranostics. 2017 Oct 12;7(18):4498-4516. doi: 10.7150/thno.17949. eCollection 2017.


Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway.

Ma X, Wang L, Huang, Li Y, Yang D, Li T, Li F, Sun L, Wei H, He K, Yu F, Zhao D, Hu L, Xing S, Liu Z, Li K, Guo J, Yang Z, Pan X, Li A, Shi Y, Wang J, Gao P, Zhang H.

Nat Commun. 2017 Nov 15;8(1):1506. doi: 10.1038/s41467-017-01647-5.


Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade.

Lue HW, Podolak J, Kolahi K, Cheng L, Rao S, Garg D, Xue CH, Rantala JK, Tyner JW, Thornburg KL, Martinez-Acevedo A, Liu JJ, Amling CL, Truillet C, Louie SM, Anderson KE, Evans MJ, O'Donnell VB, Nomura DK, Drake JM, Ritz A, Thomas GV.

Genes Dev. 2017 Oct 15;31(20):2067-2084. doi: 10.1101/gad.305292.117. Epub 2017 Nov 14.


Hypoxia favors myosin heavy chain beta gene expression in an Hif-1alpha-dependent manner.

Binó L, Procházková J, Radaszkiewicz KA, Kučera J, Kudová J, Pacherník J, Kubala L.

Oncotarget. 2017 Jul 5;8(48):83684-83697. doi: 10.18632/oncotarget.19016. eCollection 2017 Oct 13.


Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia.

Le Sommer S, Morrice N, Pesaresi M, Thompson D, Vickers MA, Murray GI, Mody N, Neel BG, Bence KK, Wilson HM, Delibegović M.

Cancer Res. 2018 Jan 1;78(1):75-87. doi: 10.1158/0008-5472.CAN-17-0946. Epub 2017 Nov 9.


Down-regulation of CHERP inhibits neuroblastoma cell proliferation and induces apoptosis through ER stress induction.

Zhang D, Wang F, Pang Y, Ke XX, Zhu S, Zhao E, Zhang K, Chen L, Cui H.

Oncotarget. 2017 Sep 15;8(46):80956-80970. doi: 10.18632/oncotarget.20898. eCollection 2017 Oct 6.


Evolving Significance and Future Relevance of Anti-Angiogenic Activity of mTOR Inhibitors in Cancer Therapy.

Faes S, Santoro T, Demartines N, Dormond O.

Cancers (Basel). 2017 Nov 1;9(11). pii: E152. doi: 10.3390/cancers9110152. Review.


The Role of Mammalian Target of Rapamycin (mTOR) in Insulin Signaling.

Yoon MS.

Nutrients. 2017 Oct 27;9(11). pii: E1176. doi: 10.3390/nu9111176. Review.


The ins and outs of endoplasmic reticulum-controlled lipid biosynthesis.

Jacquemyn J, Cascalho A, Goodchild RE.

EMBO Rep. 2017 Nov;18(11):1905-1921. doi: 10.15252/embr.201643426. Epub 2017 Oct 26. Review.


mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability.

Valvezan AJ, Turner M, Belaid A, Lam HC, Miller SK, McNamara MC, Baglini C, Housden BE, Perrimon N, Kwiatkowski DJ, Asara JM, Henske EP, Manning BD.

Cancer Cell. 2017 Nov 13;32(5):624-638.e5. doi: 10.1016/j.ccell.2017.09.013. Epub 2017 Oct 19.


Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation.

Dang EV, McDonald JG, Russell DW, Cyster JG.

Cell. 2017 Nov 16;171(5):1057-1071.e11. doi: 10.1016/j.cell.2017.09.029. Epub 2017 Oct 12.


mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors.

Malone CF, Emerson C, Ingraham R, Barbosa W, Guerra S, Yoon H, Liu LL, Michor F, Haigis M, Macleod KF, Maertens O, Cichowski K.

Cancer Discov. 2017 Dec;7(12):1450-1463. doi: 10.1158/2159-8290.CD-17-0177. Epub 2017 Sep 29.


Targeting Metabolism for Cancer Therapy.

Luengo A, Gui DY, Vander Heiden MG.

Cell Chem Biol. 2017 Sep 21;24(9):1161-1180. doi: 10.1016/j.chembiol.2017.08.028. Review.


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