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U6 snRNA expression prevents toxicity in TDP-43-knockdown cells.

Yahara M, Kitamura A, Kinjo M.

PLoS One. 2017 Nov 10;12(11):e0187813. doi: 10.1371/journal.pone.0187813. eCollection 2017.


What is "Hyper" in the ALS Hypermetabolism?

Ferri A, Coccurello R.

Mediators Inflamm. 2017;2017:7821672. doi: 10.1155/2017/7821672. Epub 2017 Sep 7. Review.


Metabolic Dysregulation in Amyotrophic Lateral Sclerosis: Challenges and Opportunities.

Joardar A, Manzo E, Zarnescu DC.

Curr Genet Med Rep. 2017 Jun;5(2):108-114. doi: 10.1007/s40142-017-0123-8. Epub 2017 Apr 28.


TDP-43/HDAC6 axis promoted tumor progression and regulated nutrient deprivation-induced autophagy in glioblastoma.

Lin TW, Chen MT, Lin LT, Huang PI, Lo WL, Yang YP, Lu KH, Chen YW, Chiou SH, Wu CW.

Oncotarget. 2017 May 18;8(34):56612-56625. doi: 10.18632/oncotarget.17979. eCollection 2017 Aug 22.


TDP-43 in the spectrum of MND-FTLD pathologies.

Heyburn L, Moussa CE.

Mol Cell Neurosci. 2017 Sep;83:46-54. doi: 10.1016/j.mcn.2017.07.001. Epub 2017 Jul 4. Review.


TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss.

Paolicelli RC, Jawaid A, Henstridge CM, Valeri A, Merlini M, Robinson JL, Lee EB, Rose J, Appel S, Lee VM, Trojanowski JQ, Spires-Jones T, Schulz PE, Rajendran L.

Neuron. 2017 Jul 19;95(2):297-308.e6. doi: 10.1016/j.neuron.2017.05.037. Epub 2017 Jun 29.


Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome.

Hosaka Y, Inoshita T, Shiba-Fukushima K, Cui C, Arano T, Imai Y, Hattori N.

EBioMedicine. 2017 Jul;21:218-227. doi: 10.1016/j.ebiom.2017.06.002. Epub 2017 Jun 8.


Quantitative analysis of cryptic splicing associated with TDP-43 depletion.

Humphrey J, Emmett W, Fratta P, Isaacs AM, Plagnol V.

BMC Med Genomics. 2017 May 26;10(1):38. doi: 10.1186/s12920-017-0274-1.


Energy Homeostasis and Abnormal RNA Metabolism in Amyotrophic Lateral Sclerosis.

Liu YJ, Tsai PY, Chern Y.

Front Cell Neurosci. 2017 May 4;11:126. doi: 10.3389/fncel.2017.00126. eCollection 2017. Review.


Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43.

Sun M, Bell W, LaClair KD, Ling JP, Han H, Kageyama Y, Pletnikova O, Troncoso JC, Wong PC, Chen LL.

Acta Neuropathol. 2017 Jun;133(6):923-931. doi: 10.1007/s00401-017-1701-2. Epub 2017 Mar 22.


Heat Shock-induced Phosphorylation of TAR DNA-binding Protein 43 (TDP-43) by MAPK/ERK Kinase Regulates TDP-43 Function.

Li W, Reeb AN, Lin B, Subramanian P, Fey EE, Knoverek CR, French RL, Bigio EH, Ayala YM.

J Biol Chem. 2017 Mar 24;292(12):5089-5100. doi: 10.1074/jbc.M116.753913. Epub 2017 Feb 6.


Tdp-43 cryptic exons are highly variable between cell types.

Jeong YH, Ling JP, Lin SZ, Donde AN, Braunstein KE, Majounie E, Traynor BJ, LaClair KD, Lloyd TE, Wong PC.

Mol Neurodegener. 2017 Feb 2;12(1):13. doi: 10.1186/s13024-016-0144-x.


Akirin2 is essential for the formation of the cerebral cortex.

Bosch PJ, Fuller LC, Sleeth CM, Weiner JA.

Neural Dev. 2016 Nov 21;11(1):21.


Energy expenditure in frontotemporal dementia: a behavioural and imaging study.

Ahmed RM, Landin-Romero R, Collet TH, van der Klaauw AA, Devenney E, Henning E, Kiernan MC, Piguet O, Farooqi IS, Hodges JR.

Brain. 2017 Jan;140(1):171-183. doi: 10.1093/brain/aww263. Epub 2016 Oct 27.


Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model.

LaClair KD, Donde A, Ling JP, Jeong YH, Chhabra R, Martin LJ, Wong PC.

Acta Neuropathol. 2016 Dec;132(6):859-873. Epub 2016 Oct 26.


TDP-43/FUS in motor neuron disease: Complexity and challenges.

Guerrero EN, Wang H, Mitra J, Hegde PM, Stowell SE, Liachko NF, Kraemer BC, Garruto RM, Rao KS, Hegde ML.

Prog Neurobiol. 2016 Oct - Nov;145-146:78-97. doi: 10.1016/j.pneurobio.2016.09.004. Epub 2016 Sep 28. Review.


Stress granules at the intersection of autophagy and ALS.

Monahan Z, Shewmaker F, Pandey UB.

Brain Res. 2016 Oct 15;1649(Pt B):189-200. doi: 10.1016/j.brainres.2016.05.022. Epub 2016 May 13. Review.


TDP-43-The key to understanding amyotrophic lateral sclerosis.

Xu Z, Yang C.

Rare Dis. 2014 Oct 30;2(1):e944443. doi: 10.4161/21675511.2014.944443. eCollection 2014.

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