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Items: 1 to 20 of 44

1.

Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways.

Liang G, Liu M, Wang Q, Shen Y, Mei H, Li D, Liu W.

Oncotarget. 2017 Apr 25;8(17):28510-28525. doi: 10.18632/oncotarget.15324.

2.

Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1.

Merzoug-Larabi M, Spasojevic C, Eymard M, Hugonin C, Auclair C, Karam M.

BMC Cancer. 2017 Jan 5;17(1):12. doi: 10.1186/s12885-016-3007-5.

3.

Osteoblasts Are the Centerpiece of the Metastatic Bone Microenvironment.

Jeong HM, Cho SW, Park SI.

Endocrinol Metab (Seoul). 2016 Dec;31(4):485-492. doi: 10.3803/EnM.2016.31.4.485. Review.

4.
5.

Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.

Faião-Flores F, Alves-Fernandes DK, Pennacchi PC, Sandri S, Vicente AL, Scapulatempo-Neto C, Vazquez VL, Reis RM, Chauhan J, Goding CR, Smalley KS, Maria-Engler SS.

Oncogene. 2017 Mar 30;36(13):1849-1861. doi: 10.1038/onc.2016.348. Epub 2016 Oct 17.

6.

Gli promotes epithelial-mesenchymal transition in human lung adenocarcinomas.

Li H, Yue D, Jin JQ, Woodard GA, Tolani B, Luh TM, Giroux-Leprieur E, Mo M, Chen Z, Che J, Zhang Z, Zhou Y, Wang L, Hao X, Jablons D, Wang C, He B.

Oncotarget. 2016 Dec 6;7(49):80415-80425. doi: 10.18632/oncotarget.11246.

7.

Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity.

Stasiak M, Boncela J, Perreau C, Karamanou K, Chatron-Colliet A, Proult I, Przygodzka P, Chakravarti S, Maquart FX, Kowalska MA, Wegrowski Y, Brézillon S.

PLoS One. 2016 Mar 1;11(3):e0150226. doi: 10.1371/journal.pone.0150226. eCollection 2016.

8.

Sonic hedgehog delivery from self-assembled nanofiber hydrogels reduces the fibrotic response in models of erectile dysfunction.

Choe S, Veliceasa D, Bond CW, Harrington DA, Stupp SI, McVary KT, Podlasek CA.

Acta Biomater. 2016 Mar 1;32:89-99. doi: 10.1016/j.actbio.2016.01.014. Epub 2016 Jan 14.

9.

Cancer stem cell vaccine expressing ESAT-6-gpi and IL-21 inhibits melanoma growth and metastases.

Zhao F, He X, Sun J, Wu D, Pan M, Li M, Wu S, Zhang R, Yan C, Dou J.

Am J Transl Res. 2015 Oct 15;7(10):1870-82. eCollection 2015.

10.

SOX18 Is a Novel Target Gene of Hedgehog Signaling in Cervical Carcinoma Cell Lines.

Petrovic I, Milivojevic M, Popovic J, Schwirtlich M, Rankovic B, Stevanovic M.

PLoS One. 2015 Nov 20;10(11):e0143591. doi: 10.1371/journal.pone.0143591. eCollection 2015.

11.

The Role of Hedgehog Signaling in Tumor Induced Bone Disease.

Cannonier SA, Sterling JA.

Cancers (Basel). 2015 Aug 26;7(3):1658-83. doi: 10.3390/cancers7030856. Review.

12.

A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity.

Conde-Perez A, Gros G, Longvert C, Pedersen M, Petit V, Aktary Z, Viros A, Gesbert F, Delmas V, Rambow F, Bastian BC, Campbell AD, Colombo S, Puig I, Bellacosa A, Sansom O, Marais R, Van Kempen LC, Larue L.

Nat Commun. 2015 Aug 26;6:8093. doi: 10.1038/ncomms9093.

13.

Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells.

Jackson DA, Smith TD, Amarsaikhan N, Han W, Neil MS, Boi SK, Vrabel AM, Tolosa EJ, Almada LL, Fernandez-Zapico ME, Elsawa SF.

J Immunol. 2015 Sep 15;195(6):2908-16. doi: 10.4049/jimmunol.1402974. Epub 2015 Aug 3.

14.

Hedgehog signaling inhibitors as anti-cancer agents in osteosarcoma.

Kumar RM, Fuchs B.

Cancers (Basel). 2015 May 13;7(2):784-94. doi: 10.3390/cancers7020784. Review.

15.

Combining TGF-β1 knockdown and miR200c administration to optimize antitumor efficacy of B16F10/GPI-IL-21 vaccine.

Wang X, Zhao F, He X, Wang J, Zhang Y, Zhang H, Ni Y, Sun J, Wang X, Dou J.

Oncotarget. 2015 May 20;6(14):12493-504.

16.

Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation.

Nallet-Staub F, Yin X, Gilbert C, Marsaud V, Ben Mimoun S, Javelaud D, Leof EB, Mauviel A.

Dev Cell. 2015 Mar 9;32(5):640-51. doi: 10.1016/j.devcel.2015.01.011.

17.

The versatile functions of Sox9 in development, stem cells, and human diseases.

Jo A, Denduluri S, Zhang B, Wang Z, Yin L, Yan Z, Kang R, Shi LL, Mok J, Lee MJ, Haydon RC.

Genes Dis. 2014 Dec;1(2):149-161.

18.

Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy.

Pandolfi S, Stecca B.

Expert Rev Mol Med. 2015 Feb 9;17:e5. doi: 10.1017/erm.2015.3. Review.

19.

Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity.

Vandamme N, Berx G.

Front Oncol. 2014 Dec 9;4:352. doi: 10.3389/fonc.2014.00352. eCollection 2014. Review.

20.

Hedgehog signalling pathway: carcinogenesis and targeted therapy.

Ebrahimi A, Larijani L, Moradi A, Ebrahimi MR.

Iran J Cancer Prev. 2013 Winter;6(1):36-43. Review.

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