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DHA increases adiponectin expression more effectively than EPA at relative low concentrations by regulating PPARγ and its phosphorylation at Ser273 in 3T3-L1 adipocytes.

Song J, Li C, Lv Y, Zhang Y, Amakye WK, Mao L.

Nutr Metab (Lond). 2017 Aug 11;14:52. doi: 10.1186/s12986-017-0209-z. eCollection 2017.


Discovery of Novel Insulin Sensitizers: Promising Approaches and Targets.

Chen Y, Ma H, Zhu D, Zhao G, Wang L, Fu X, Chen W.

PPAR Res. 2017;2017:8360919. doi: 10.1155/2017/8360919. Epub 2017 Jun 4. Review.


Targeting Peroxisome Proliferator-Activated Receptors Using Thiazolidinediones: Strategy for Design of Novel Antidiabetic Drugs.

Thangavel N, Al Bratty M, Akhtar Javed S, Ahsan W, Alhazmi HA.

Int J Med Chem. 2017;2017:1069718. doi: 10.1155/2017/1069718. Epub 2017 Jun 5. Review.


Synaptic roles of cyclin-dependent kinase 5 & its implications in epilepsy.

Dixit AB, Banerjee J, Tripathi M, Sarkar C, Chandra PS.

Indian J Med Res. 2017 Feb;145(2):179-188. doi: 10.4103/ijmr.IJMR_1249_14. Review.


Selective Tissue Distribution Mediates Tissue-Dependent PPARγ Activation and Insulin Sensitization by INT131, a Selective PPARγ Modulator.

Xie X, Chen W, Zhang N, Yuan M, Xu C, Zheng Z, Li H, Wang L.

Front Pharmacol. 2017 May 30;8:317. doi: 10.3389/fphar.2017.00317. eCollection 2017.


Obesity-Linked Phosphorylation of SIRT1 by Casein Kinase 2 Inhibits Its Nuclear Localization and Promotes Fatty Liver.

Choi SE, Kwon S, Seok S, Xiao Z, Lee KW, Kang Y, Li X, Shinoda K, Kajimura S, Kemper B, Kemper JK.

Mol Cell Biol. 2017 Jul 14;37(15). pii: e00006-17. doi: 10.1128/MCB.00006-17. Print 2017 Aug 1.


Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression.

Nam M, Akie TE, Sanosaka M, Craige SM, Kant S, Keaney JF Jr, Cooper MP.

Sci Rep. 2017 May 17;7(1):2013. doi: 10.1038/s41598-017-01879-x.


Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics.

Frkic RL, He Y, Rodriguez BB, Chang MR, Kuruvilla D, Ciesla A, Abell AD, Kamenecka TM, Griffin PR, Bruning JB.

J Med Chem. 2017 Jun 8;60(11):4584-4593. doi: 10.1021/acs.jmedchem.6b01727. Epub 2017 May 22.


Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase.

Hu R, Yan H, Fei X, Liu H, Wu J.

Sci Rep. 2017 Apr 10;7(1):778. doi: 10.1038/s41598-017-00925-y.


Expression of CRM1 and CDK5 shows high prognostic accuracy for gastric cancer.

Sun YQ, Xie JW, Xie HT, Chen PC, Zhang XL, Zheng CH, Li P, Wang JB, Lin JX, Cao LL, Huang CM, Lin Y.

World J Gastroenterol. 2017 Mar 21;23(11):2012-2022. doi: 10.3748/wjg.v23.i11.2012.


Investigations on Binding Pattern of Kinase Inhibitors with PPARγ: Molecular Docking, Molecular Dynamic Simulations, and Free Energy Calculation Studies.

Mazumder M, Ponnan P, Das U, Gourinath S, Khan HA, Yang J, Sakharkar MK.

PPAR Res. 2017;2017:6397836. doi: 10.1155/2017/6397836. Epub 2017 Feb 22.


Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.

Wu CC, Baiga TJ, Downes M, La Clair JJ, Atkins AR, Richard SB, Fan W, Stockley-Noel TA, Bowman ME, Noel JP, Evans RM.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2563-E2570. doi: 10.1073/pnas.1621513114. Epub 2017 Mar 20.


Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy.

Yamaguchi S, Yoshino J.

Bioessays. 2017 May;39(5). doi: 10.1002/bies.201600227. Epub 2017 Mar 15. Review.


MicroRNA-27a promotes podocyte injury via PPARγ-mediated β-catenin activation in diabetic nephropathy.

Zhou Z, Wan J, Hou X, Geng J, Li X, Bai X.

Cell Death Dis. 2017 Mar 9;8(3):e2658. doi: 10.1038/cddis.2017.74.


Regulation of Stomatal Immunity by Interdependent Functions of a Pathogen-Responsive MPK3/MPK6 Cascade and Abscisic Acid.

Su J, Zhang M, Zhang L, Sun T, Liu Y, Lukowitz W, Xu J, Zhang S.

Plant Cell. 2017 Mar;29(3):526-542. doi: 10.1105/tpc.16.00577. Epub 2017 Mar 2.


Phosphoproteome Discovery in Human Biological Fluids.

Giorgianni F, Beranova-Giorgianni S.

Proteomes. 2016 Dec 1;4(4). pii: E37. doi: 10.3390/proteomes4040037. Review.


PPARγ and Its Role in Cardiovascular Diseases.

Chandra M, Miriyala S, Panchatcharam M.

PPAR Res. 2017;2017:6404638. doi: 10.1155/2017/6404638. Epub 2017 Jan 24. Review.


A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability.

Vasaturo M, Fiengo L, De Tommasi N, Sabatino L, Ziccardi P, Colantuoni V, Bruno M, Cerchia C, Novellino E, Lupo A, Lavecchia A, Piaz FD.

Sci Rep. 2017 Jan 24;7:41273. doi: 10.1038/srep41273.


Sexual dimorphisms in genetic loci linked to body fat distribution.

Pulit SL, Karaderi T, Lindgren CM.

Biosci Rep. 2017 Feb 3;37(1). pii: BSR20160184. doi: 10.1042/BSR20160184. Print 2017 Feb 28. Review.


C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ.

Kim JH, Shin S, Seo J, Lee EW, Jeong M, Lee MS, Han HJ, Song J.

Sci Rep. 2017 Jan 6;7:40023. doi: 10.1038/srep40023.

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