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Items: 15


Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy.

Fong RH, Banik SS, Mattia K, Barnes T, Tucker D, Liss N, Lu K, Selvarajah S, Srinivasan S, Mabila M, Miller A, Muench MO, Michault A, Rucker JB, Paes C, Simmons G, Kahle KM, Doranz BJ.

J Virol. 2014 Dec;88(24):14364-79. doi: 10.1128/JVI.01943-14. Epub 2014 Oct 1.


Locking and blocking the viral landscape of an alphavirus with neutralizing antibodies.

Porta J, Jose J, Roehrig JT, Blair CD, Kuhn RJ, Rossmann MG.

J Virol. 2014 Sep 1;88(17):9616-23. doi: 10.1128/JVI.01286-14. Epub 2014 Jun 11.


Human-like antibodies neutralizing Western equine encephalitis virus.

Hülseweh B, Rülker T, Pelat T, Langermann C, Frenzel A, Schirrmann T, Dübel S, Thullier P, Hust M.

MAbs. 2014 May-Jun;6(3):718-27. doi: 10.4161/mabs.28170. Epub 2014 Feb 11.


Identical strength of the T cell responses against E2, nsP1 and capsid CHIKV proteins in recovered and chronic patients after the epidemics of 2005-2006 in La Reunion Island.

Hoarau JJ, Gay F, Pellé O, Samri A, Jaffar-Bandjee MC, Gasque P, Autran B.

PLoS One. 2013 Dec 23;8(12):e84695. doi: 10.1371/journal.pone.0084695. eCollection 2013.


Comprehensive mapping of common immunodominant epitopes in the eastern equine encephalitis virus E2 protein recognized by avian antibody responses.

Sun E, Zhao J, Sun L, Xu Q, Yang T, Qin Y, Wang W, Wei P, Sun J, Wu D.

PLoS One. 2013 Jul 26;8(7):e69349. doi: 10.1371/journal.pone.0069349. Print 2013.


IRES-driven expression of the capsid protein of the Venezuelan equine encephalitis virus TC-83 vaccine strain increases its attenuation and safety.

Guerbois M, Volkova E, Forrester NL, Rossi SL, Frolov I, Weaver SC.

PLoS Negl Trop Dis. 2013 May 9;7(5):e2197. doi: 10.1371/journal.pntd.0002197. Print 2013.


Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.

Sun S, Xiang Y, Akahata W, Holdaway H, Pal P, Zhang X, Diamond MS, Nabel GJ, Rossmann MG.

Elife. 2013 Apr 2;2:e00435. doi: 10.7554/eLife.00435.


Isolation and characterisation of a human-like antibody fragment (scFv) that inactivates VEEV in vitro and in vivo.

Rülker T, Voß L, Thullier P, O' Brien LM, Pelat T, Perkins SD, Langermann C, Schirrmann T, Dübel S, Marschall HJ, Hust M, Hülseweh B.

PLoS One. 2012;7(5):e37242. doi: 10.1371/journal.pone.0037242. Epub 2012 May 30.


Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.

Kam YW, Lum FM, Teo TH, Lee WW, Simarmata D, Harjanto S, Chua CL, Chan YF, Wee JK, Chow A, Lin RT, Leo YS, Le Grand R, Sam IC, Tong JC, Roques P, Wiesmüller KH, Rénia L, Rötzschke O, Ng LF.

EMBO Mol Med. 2012 Apr;4(4):330-43. doi: 10.1002/emmm.201200213. Epub 2012 Mar 5.


A humanized IgG but not IgM antibody is effective in prophylaxis and therapy of yellow fever infection in an AG129/17D-204 peripheral challenge mouse model.

Thibodeaux BA, Garbino NC, Liss NM, Piper J, Schlesinger JJ, Blair CD, Roehrig JT.

Antiviral Res. 2012 Apr;94(1):1-8. doi: 10.1016/j.antiviral.2012.02.001. Epub 2012 Feb 15.


Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants.

Lee CY, Kam YW, Fric J, Malleret B, Koh EG, Prakash C, Huang W, Lee WW, Lin C, Lin RT, Renia L, Wang CI, Ng LF, Warter L.

PLoS Pathog. 2011 Dec;7(12):e1002390. doi: 10.1371/journal.ppat.1002390. Epub 2011 Dec 1.


Antibodies for biodefense.

Froude JW, Stiles B, Pelat T, Thullier P.

MAbs. 2011 Nov-Dec;3(6):517-27. doi: 10.4161/mabs.3.6.17621. Epub 2011 Nov 1. Review.


4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus.

Zhang R, Hryc CF, Cong Y, Liu X, Jakana J, Gorchakov R, Baker ML, Weaver SC, Chiu W.

EMBO J. 2011 Aug 9;30(18):3854-63. doi: 10.1038/emboj.2011.261.


The structure of barmah forest virus as revealed by cryo-electron microscopy at a 6-angstrom resolution has detailed transmembrane protein architecture and interactions.

Kostyuchenko VA, Jakana J, Liu X, Haddow AD, Aung M, Weaver SC, Chiu W, Lok SM.

J Virol. 2011 Sep;85(18):9327-33. doi: 10.1128/JVI.05015-11. Epub 2011 Jul 13.


Treatment of mice with human monoclonal antibody 24h after lethal aerosol challenge with virulent Venezuelan equine encephalitis virus prevents disease but not infection.

Hunt AR, Bowen RA, Frederickson S, Maruyama T, Roehrig JT, Blair CD.

Virology. 2011 Jun 5;414(2):146-52. doi: 10.1016/j.virol.2011.03.016. Epub 2011 Apr 13.

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