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Items: 1 to 20 of 36


Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana.

Hale CJ, Potok ME, Lopez J, Do T, Liu A, Gallego-Bartolome J, Michaels SD, Jacobsen SE.

PLoS Genet. 2016 Jun 2;12(6):e1006092. doi: 10.1371/journal.pgen.1006092. eCollection 2016 Jun.


Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5.

Meyer PA, Li S, Zhang M, Yamada K, Takagi Y, Hartzog GA, Fu J.

Mol Cell Biol. 2015 Oct;35(19):3354-69. doi: 10.1128/MCB.00520-15. Epub 2015 Jul 27.


Genetic instability in budding and fission yeast-sources and mechanisms.

Skoneczna A, Kaniak A, Skoneczny M.

FEMS Microbiol Rev. 2015 Nov;39(6):917-67. doi: 10.1093/femsre/fuv028. Epub 2015 Jun 24. Review.


Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity.

Cusanelli E, Chartrand P.

Front Genet. 2015 Apr 14;6:143. doi: 10.3389/fgene.2015.00143. eCollection 2015. Review.


Co-transcriptional mRNP formation is coordinated within a molecular mRNP packaging station in S. cerevisiae.

Meinel DM, Sträßer K.

Bioessays. 2015 Jun;37(6):666-77. doi: 10.1002/bies.201400220. Epub 2015 Mar 20. Review.


Role of TERRA in the regulation of telomere length.

Wang C, Zhao L, Lu S.

Int J Biol Sci. 2015 Feb 5;11(3):316-23. doi: 10.7150/ijbs.10528. eCollection 2015. Review.


A genome-wide function of THSC/TREX-2 at active genes prevents transcription-replication collisions.

Santos-Pereira JM, García-Rubio ML, González-Aguilera C, Luna R, Aguilera A.

Nucleic Acids Res. 2014 Oct 29;42(19):12000-14. doi: 10.1093/nar/gku906. Epub 2014 Oct 7.


The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability.

Hamperl S, Cimprich KA.

DNA Repair (Amst). 2014 Jul;19:84-94. doi: 10.1016/j.dnarep.2014.03.023. Epub 2014 Apr 18. Review.


Npl3, a new link between RNA-binding proteins and the maintenance of genome integrity.

Santos-Pereira JM, Herrero AB, Moreno S, Aguilera A.

Cell Cycle. 2014;13(10):1524-9. doi: 10.4161/cc.28708. Epub 2014 Apr 2.


Cleavage factor I links transcription termination to DNA damage response and genome integrity maintenance in Saccharomyces cerevisiae.

Gaillard H, Aguilera A.

PLoS Genet. 2014 Mar 6;10(3):e1004203. doi: 10.1371/journal.pgen.1004203. eCollection 2014 Mar.


The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming.

Wang L, Miao YL, Zheng X, Lackford B, Zhou B, Han L, Yao C, Ward JM, Burkholder A, Lipchina I, Fargo DC, Hochedlinger K, Shi Y, Williams CJ, Hu G.

Cell Stem Cell. 2013 Dec 5;13(6):676-90. doi: 10.1016/j.stem.2013.10.008.


The Npl3 hnRNP prevents R-loop-mediated transcription-replication conflicts and genome instability.

Santos-Pereira JM, Herrero AB, García-Rubio ML, Marín A, Moreno S, Aguilera A.

Genes Dev. 2013 Nov 15;27(22):2445-58. doi: 10.1101/gad.229880.113.


The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening.

Pfeiffer V, Crittin J, Grolimund L, Lingner J.

EMBO J. 2013 Oct 30;32(21):2861-71. doi: 10.1038/emboj.2013.217. Epub 2013 Oct 1.


The prefoldin complex regulates chromatin dynamics during transcription elongation.

Millán-Zambrano G, Rodríguez-Gil A, Peñate X, de Miguel-Jiménez L, Morillo-Huesca M, Krogan N, Chávez S.

PLoS Genet. 2013;9(9):e1003776. doi: 10.1371/journal.pgen.1003776. Epub 2013 Sep 19.


A transcriptome-wide atlas of RNP composition reveals diverse classes of mRNAs and lncRNAs.

Tuck AC, Tollervey D.

Cell. 2013 Aug 29;154(5):996-1009. doi: 10.1016/j.cell.2013.07.047.


A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia.

Di Gregorio E, Bianchi FT, Schiavi A, Chiotto AM, Rolando M, Verdun di Cantogno L, Grosso E, Cavalieri S, Calcia A, Lacerenza D, Zuffardi O, Retta SF, Stevanin G, Marelli C, Durr A, Forlani S, Chelly J, Montarolo F, Tempia F, Beggs HE, Reed R, Squadrone S, Abete MC, Brussino A, Ventura N, Di Cunto F, Brusco A.

J Med Genet. 2013 Aug;50(8):543-51. doi: 10.1136/jmedgenet-2013-101542. Epub 2013 Jun 7.


Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I.

Katahira J, Okuzaki D, Inoue H, Yoneda Y, Maehara K, Ohkawa Y.

Nucleic Acids Res. 2013 Aug;41(14):7060-72. doi: 10.1093/nar/gkt414. Epub 2013 May 17.


R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus.

Sun Q, Csorba T, Skourti-Stathaki K, Proudfoot NJ, Dean C.

Science. 2013 May 3;340(6132):619-21. doi: 10.1126/science.1234848.


Back to the origin: reconsidering replication, transcription, epigenetics, and cell cycle control.

Evertts AG, Coller HA.

Genes Cancer. 2012 Nov;3(11-12):678-96. doi: 10.1177/1947601912474891.


A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA.

García-Oliver E, Pascual-García P, García-Molinero V, Lenstra TL, Holstege FC, Rodríguez-Navarro S.

Nucleic Acids Res. 2013 Jun;41(11):5655-68. doi: 10.1093/nar/gkt272. Epub 2013 Apr 17.

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