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Items: 1 to 20 of 51

1.

PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription.

Faust TB, Li Y, Jang GM, Johnson JR, Yang S, Weiss A, Krogan NJ, Frankel AD.

Sci Rep. 2017 Mar 27;7:45394. doi: 10.1038/srep45394.

2.

MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding.

Asamitsu K, Hirokawa T, Okamoto T.

PLoS One. 2017 Feb 8;12(2):e0171727. doi: 10.1371/journal.pone.0171727. eCollection 2017.

3.

Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer.

Liu X, Gao Y, Ye H, Gerrin S, Ma F, Wu Y, Zhang T, Russo J, Cai C, Yuan X, Liu J, Chen S, Balk SP.

Nucleic Acids Res. 2017 Apr 20;45(7):3738-3751. doi: 10.1093/nar/gkw1291.

4.

Functional Segregation of Overlapping Genes in HIV.

Fernandes JD, Faust TB, Strauli NB, Smith C, Crosby DC, Nakamura RL, Hernandez RD, Frankel AD.

Cell. 2016 Dec 15;167(7):1762-1773.e12. doi: 10.1016/j.cell.2016.11.031.

PMID:
27984726
5.

Solution structure of the 5'-terminal hairpin of the 7SK small nuclear RNA.

Bourbigot S, Dock-Bregeon AC, Eberling P, Coutant J, Kieffer B, Lebars I.

RNA. 2016 Dec;22(12):1844-1858. Epub 2016 Oct 20.

PMID:
27852926
6.

Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb.

C Quaresma AJ, Bugai A, Barboric M.

Nucleic Acids Res. 2016 Sep 19;44(16):7527-39. doi: 10.1093/nar/gkw585. Epub 2016 Jul 1.

7.

Transcription elongation control by the 7SK snRNP complex: Releasing the pause.

McNamara RP, Bacon CW, D'Orso I.

Cell Cycle. 2016 Aug 17;15(16):2115-2123. Epub 2016 May 6.

8.

7SKiing on chromatin: Move globally, act locally.

D'Orso I.

RNA Biol. 2016 Jun 2;13(6):545-53. doi: 10.1080/15476286.2016.1181254. Epub 2016 Apr 29.

9.

Functional interplay between PPM1G and the transcription elongation machinery.

Gudipaty SA, D'Orso I.

RNA Dis. 2016;3(1). pii: e1215. Epub 2016 Mar 14.

10.

7SK-BAF axis controls pervasive transcription at enhancers.

Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY.

Nat Struct Mol Biol. 2016 Mar;23(3):231-8. doi: 10.1038/nsmb.3176. Epub 2016 Feb 15.

11.

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.

McNamara RP, Reeder JE, McMillan EA, Bacon CW, McCann JL, D'Orso I.

Mol Cell. 2016 Jan 7;61(1):39-53. doi: 10.1016/j.molcel.2015.11.004. Epub 2015 Dec 24.

12.

HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells.

Reeder JE, Kwak YT, McNamara RP, Forst CV, D'Orso I.

Elife. 2015 Oct 21;4. pii: e08955. doi: 10.7554/eLife.08955.

13.

PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.

Gudipaty SA, McNamara RP, Morton EL, D'Orso I.

Mol Cell Biol. 2015 Nov;35(22):3810-28. doi: 10.1128/MCB.00226-15. Epub 2015 Aug 31.

14.

RNA-Mediated Regulation of HMGA1 Function.

Benecke AG, Eilebrecht S.

Biomolecules. 2015;5(2):943-57. Review.

15.

Targeting HIV transcription: the quest for a functional cure.

Mousseau G, Mediouni S, Valente ST.

Curr Top Microbiol Immunol. 2015;389:121-45. doi: 10.1007/82_2015_435. Review.

16.

HIV-1 transcription is regulated by splicing factor SRSF1.

Paz S, Krainer AR, Caputi M.

Nucleic Acids Res. 2014 Dec 16;42(22):13812-23.

17.

Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat.

Jadlowsky JK, Wong JY, Graham AC, Dobrowolski C, Devor RL, Adams MD, Fujinaga K, Karn J.

Mol Cell Biol. 2014 Jun;34(11):1911-28. doi: 10.1128/MCB.01013-13. Epub 2014 Mar 17.

18.

HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters.

Eilebrecht S, Le Douce V, Riclet R, Targat B, Hallay H, Van Driessche B, Schwartz C, Robette G, Van Lint C, Rohr O, Benecke AG.

Nucleic Acids Res. 2014 Apr;42(8):4962-71. doi: 10.1093/nar/gku168. Epub 2014 Mar 11.

19.

Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure.

Mbonye U, Karn J.

Virology. 2014 Apr;454-455:328-39. doi: 10.1016/j.virol.2014.02.008. Epub 2014 Feb 22. Review.

20.

An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription.

Giraud M, Jmari N, Du L, Carallis F, Nieland TJ, Perez-Campo FM, Bensaude O, Root DE, Hacohen N, Mathis D, Benoist C.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1491-6. doi: 10.1073/pnas.1323535111. Epub 2014 Jan 16.

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