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"Pumping iron"-how macrophages handle iron at the systemic, microenvironmental, and cellular levels.

Nairz M, Theurl I, Swirski FK, Weiss G.

Pflugers Arch. 2017 Apr;469(3-4):397-418. doi: 10.1007/s00424-017-1944-8. Epub 2017 Mar 1. Review.


Modelling Systemic Iron Regulation during Dietary Iron Overload and Acute Inflammation: Role of Hepcidin-Independent Mechanisms.

Enculescu M, Metzendorf C, Sparla R, Hahnel M, Bode J, Muckenthaler MU, Legewie S.

PLoS Comput Biol. 2017 Jan 9;13(1):e1005322. doi: 10.1371/journal.pcbi.1005322. eCollection 2017 Jan.


Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis.

Duarte TL, Caldas C, Santos AG, Silva-Gomes S, Santos-Gonçalves A, Martins MJ, Porto G, Lopes JM.

Redox Biol. 2017 Apr;11:157-169. doi: 10.1016/j.redox.2016.11.013. Epub 2016 Dec 1.


Key-interventions derived from three evidence based guidelines for management and follow-up of patients with HFE haemochromatosis.

Vanclooster A, Wollersheim H, Vanhaecht K, Swinkels D, Aertgeerts B, Cassiman D; Haemochromatosis working group..

BMC Health Serv Res. 2016 Oct 13;16(1):573.


Hereditary Hemochromatosis Predisposes Mice to Yersinia pseudotuberculosis Infection Even in the Absence of the Type III Secretion System.

Miller HK, Schwiesow L, Au-Yeung W, Auerbuch V.

Front Cell Infect Microbiol. 2016 Jun 24;6:69. doi: 10.3389/fcimb.2016.00069. eCollection 2016.


Clinical-Pathological Conference Series from the Medical University of Graz : Case No 159: 52-year-old patient with psoriasis and arthralgia of the finger joints.

Fabian E, Schiller D, Graninger W, Langner C, Frei J, Schoellnast H, Alibegovic V, Stauber R, Schoefl R, Krejs GJ.

Wien Klin Wochenschr. 2016 Nov;128(21-22):846-853. Epub 2016 Jun 30. No abstract available.


Detection of a rare mutation in the ferroportin gene through targeted next generation sequencing.

Ferbo L, Manzini PM, Badar S, Campostrini N, Ferrarini A, Delledonne M, Francisci T, Tassi V, Valfrè A, Dall'omo AM, D'antico S, Girelli D, Roetto A, De Gobbi M.

Blood Transfus. 2016 Apr 28;14(6):531-534. doi: 10.2450/2016.0286-15. [Epub ahead of print] No abstract available.


Non-Heme Iron Absorption and Utilization from Typical Whole Chinese Diets in Young Chinese Urban Men Measured by a Double-Labeled Stable Isotope Technique.

Yang L, Zhang Y, Wang J, Huang Z, Gou L, Wang Z, Ren T, Piao J, Yang X.

PLoS One. 2016 Apr 21;11(4):e0153885. doi: 10.1371/journal.pone.0153885. eCollection 2016.


Hepcidin: A Promising Therapeutic Target for Iron Disorders: A Systematic Review.

Liu J, Sun B, Yin H, Liu S.

Medicine (Baltimore). 2016 Apr;95(14):e3150. doi: 10.1097/MD.0000000000003150. Review.


Dual Role of ROS as Signal and Stress Agents: Iron Tips the Balance in favor of Toxic Effects.

Gammella E, Recalcati S, Cairo G.

Oxid Med Cell Longev. 2016;2016:8629024. doi: 10.1155/2016/8629024. Epub 2016 Feb 24. Review.


Management of human factors engineering-associated hemochromatosis: A 2015 update.

Sivakumar M, Powell LW.

World J Hepatol. 2016 Mar 18;8(8):395-400. doi: 10.4254/wjh.v8.i8.395. Review.


Effect of Hfe Deficiency on Memory Capacity and Motor Coordination after Manganese Exposure by Drinking Water in Mice.

Alsulimani HH, Ye Q, Kim J.

Toxicol Res. 2015 Dec;31(4):347-54. doi: 10.5487/TR.2015.31.4.347.


Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.

Podmore C, Meidtner K, Schulze MB, Scott RA, Ramond A, Butterworth AS, Di Angelantonio E, Danesh J, Arriola L, Barricarte A, Boeing H, Clavel-Chapelon F, Cross AJ, Dahm CC, Fagherazzi G, Franks PW, Gavrila D, Grioni S, Gunter MJ, Gusto G, Jakszyn P, Katzke V, Key TJ, Kühn T, Mattiello A, Nilsson PM, Olsen A, Overvad K, Palli D, Quirós JR, Rolandsson O, Sacerdote C, Sánchez-Cantalejo E, Slimani N, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, van der Schouw YT, Feskens EJ, Forouhi NG, Sharp SJ, Riboli E, Langenberg C, Wareham NJ.

Diabetes Care. 2016 Apr;39(4):572-81. doi: 10.2337/dc15-0257. Epub 2016 Feb 9.


Iron Homeostasis in Health and Disease.

Gozzelino R, Arosio P.

Int J Mol Sci. 2016 Jan 20;17(1). pii: E130. doi: 10.3390/ijms17010130. Review.


Tipping the balance: Haemoglobinopathies and the risk of diabetes.

Baldwin HJ, Green AE, Spellar KM, Arthur PJ, Phillips HG, Patel JV.

World J Diabetes. 2016 Jan 10;7(1):8-13. doi: 10.4239/wjd.v7.i1.8.


Regulation of iron homeostasis by the p53-ISCU pathway.

Funauchi Y, Tanikawa C, Yi Lo PH, Mori J, Daigo Y, Takano A, Miyagi Y, Okawa A, Nakamura Y, Matsuda K.

Sci Rep. 2015 Nov 12;5:16497. doi: 10.1038/srep16497.


Carriers of the Complex Allele HFE c.[187C>G;340+4T>C] Have Increased Risk of Iron Overload in São Miguel Island Population (Azores, Portugal).

Branco CC, Gomes CT, De Fez L, Bulhões S, Brilhante MJ, Pereirinha T, Cabral R, Rego AC, Fraga C, Miguel AG, Brasil G, Macedo P, Mota-Vieira L.

PLoS One. 2015 Oct 26;10(10):e0140228. doi: 10.1371/journal.pone.0140228. eCollection 2015.


Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network.

Gallego CJ, Burt A, Sundaresan AS, Ye Z, Shaw C, Crosslin DR, Crane PK, Fullerton SM, Hansen K, Carrell D, Kuivaniemi H, Derr K, de Andrade M, McCarty CA, Kitchner TE, Ragon BK, Stallings SC, Papa G, Bochenek J, Smith ME, Aufox SA, Pacheco JA, Patel V, Friesema EM, Erwin AL, Gottesman O, Gerhard GS, Ritchie M, Motulsky AG, Kullo IJ, Larson EB, Tromp G, Brilliant MH, Bottinger E, Denny JC, Roden DM, Williams MS, Jarvik GP.

Am J Hum Genet. 2015 Oct 1;97(4):512-20. doi: 10.1016/j.ajhg.2015.08.008. Epub 2015 Sep 10.


Copper Accumulates in Hemosiderins in Livers of Patients with Iron Overload Syndromes.

Ono Y, Ishigami M, Hayashi K, Wakusawa S, Hayashi H, Kumagai K, Morotomi N, Yamashita T, Kawanaka M, Watanabe M, Ozawa H, Tai M, Miyajima H, Yoshioka K, Hirooka Y, Goto H.

J Clin Transl Hepatol. 2015 Jun 28;3(2):85-92. doi: 10.14218/JCTH.2015.00004. Epub 2015 Jun 15.


Cellular sensing and transport of metal ions: implications in micronutrient homeostasis.

Bird AJ.

J Nutr Biochem. 2015 Nov;26(11):1103-15. doi: 10.1016/j.jnutbio.2015.08.002. Epub 2015 Aug 7. Review.

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