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Items: 1 to 20 of 26


Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications.

Zenata O, Vrzal R.

Oncotarget. 2017 May 23;8(21):35390-35402. doi: 10.18632/oncotarget.15697. Review.


H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis.

Zhang X, Li B, Rezaeian AH, Xu X, Chou PC, Jin G, Han F, Pan BS, Wang CY, Long J, Zhang A, Huang CY, Tsai FJ, Tsai CH, Logothetis C, Lin HK.

Nat Commun. 2017 Mar 16;8:14799. doi: 10.1038/ncomms14799.


Nitric-oxide synthase trafficking inducer is a pleiotropic regulator of endothelial cell function and signaling.

Chakraborty S, Ain R.

J Biol Chem. 2017 Apr 21;292(16):6600-6620. doi: 10.1074/jbc.M116.742627. Epub 2017 Feb 24.


K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression.

Wu HT, Kuo YC, Hung JJ, Huang CH, Chen WY, Chou TY, Chen Y, Chen YJ, Chen YJ, Cheng WC, Teng SC, Wu KJ.

Nat Commun. 2016 Dec 9;7:13644. doi: 10.1038/ncomms13644.


A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis.

Rezaeian AH, Li CF, Wu CY, Zhang X, Delacerda J, You MJ, Han F, Cai Z, Jeong YS, Jin G, Phan L, Chou PC, Lee MH, Hung MC, Sarbassov D, Lin HK.

Nat Cell Biol. 2017 Jan;19(1):38-51. doi: 10.1038/ncb3445. Epub 2016 Dec 5.


The Linear Ubiquitin Assembly Complex Modulates Latent Membrane Protein 1 Activation of NF-κB and Interferon Regulatory Factor 7.

Wang L, Wang Y, Zhao J, Ren J, Hall KH, Moorman JP, Yao ZQ, Ning S.

J Virol. 2017 Jan 31;91(4). pii: e01138-16. doi: 10.1128/JVI.01138-16. Print 2017 Feb 15.


E3 ubiquitin ligase NKLAM ubiquitinates STAT1 and positively regulates STAT1-mediated transcriptional activity.

Lawrence DW, Kornbluth J.

Cell Signal. 2016 Dec;28(12):1833-1841. doi: 10.1016/j.cellsig.2016.08.014. Epub 2016 Aug 26.


miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression.

Cui X, Kong C, Zhu Y, Zeng Y, Zhang Z, Liu X, Zhan B, Piao C, Jiang Z.

Oncotarget. 2016 Jul 26;7(30):48547-48561. doi: 10.18632/oncotarget.10423.


Role of Ubiquitin-Mediated Degradation System in Plant Biology.

Sharma B, Joshi D, Yadav PK, Gupta AK, Bhatt TK.

Front Plant Sci. 2016 Jun 8;7:806. doi: 10.3389/fpls.2016.00806. eCollection 2016. Review.


Targeting ubiquitination for cancer therapies.

Morrow JK, Lin HK, Sun SC, Zhang S.

Future Med Chem. 2015;7(17):2333-50. doi: 10.4155/fmc.15.148. Epub 2015 Dec 2. Review.


Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.

Heo J, Eki R, Abbas T.

Semin Cancer Biol. 2016 Feb;36:33-51. doi: 10.1016/j.semcancer.2015.09.015. Epub 2015 Sep 30. Review.


Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis.

Xu D, Li CF, Zhang X, Gong Z, Chan CH, Lee SW, Jin G, Rezaeian AH, Han F, Wang J, Yang WL, Feng ZZ, Chen W, Wu CY, Wang YJ, Chow LP, Zhu XF, Zeng YX, Lin HK.

Nat Commun. 2015 Mar 30;6:6641. doi: 10.1038/ncomms7641.


Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.

Lee SW, Li CF, Jin G, Cai Z, Han F, Chan CH, Yang WL, Li BK, Rezaeian AH, Li HY, Huang HY, Lin HK.

Mol Cell. 2015 Mar 19;57(6):1022-33. doi: 10.1016/j.molcel.2015.01.015. Epub 2015 Feb 26.


Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling.

Gallo LH, Meyer AN, Motamedchaboki K, Nelson KN, Haas M, Donoghue DJ.

Cell Cycle. 2014;13(24):3964-76. doi: 10.4161/15384101.2014.988026.


F-box only protein 31 (FBXO31) negatively regulates p38 mitogen-activated protein kinase (MAPK) signaling by mediating lysine 48-linked ubiquitination and degradation of mitogen-activated protein kinase kinase 6 (MKK6).

Liu J, Han L, Li B, Yang J, Huen MS, Pan X, Tsao SW, Cheung AL.

J Biol Chem. 2014 Aug 1;289(31):21508-18. doi: 10.1074/jbc.M114.560342. Epub 2014 Jun 16.


The expression and clinical significance of HERC4 in breast cancer.

Zhou H, Shi R, Wei M, Zheng WL, Zhou JY, Ma WL.

Cancer Cell Int. 2013 Nov 14;13(1):113. doi: 10.1186/1475-2867-13-113.


Cycles of ubiquitination and deubiquitination critically regulate growth factor-mediated activation of Akt signaling.

Yang WL, Jin G, Li CF, Jeong YS, Moten A, Xu D, Feng Z, Chen W, Cai Z, Darnay B, Gu W, Lin HK.

Sci Signal. 2013 Jan 8;6(257):ra3. doi: 10.1126/scisignal.2003197.


The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis.

Tu Y, Chen C, Pan J, Xu J, Zhou ZG, Wang CY.

Int J Clin Exp Pathol. 2012;5(8):726-38. Epub 2012 Oct 1. Review.


A ubiquitin ligase of symbiosis receptor kinase involved in nodule organogenesis.

Yuan S, Zhu H, Gou H, Fu W, Liu L, Chen T, Ke D, Kang H, Xie Q, Hong Z, Zhang Z.

Plant Physiol. 2012 Sep;160(1):106-17. doi: 10.1104/pp.112.199000. Epub 2012 Jul 20.

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