Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 20

1.

The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells.

Raza S, Meyer M, Goodyear C, Hammer KDP, Guo B, Ghribi O.

Cancer Cell Int. 2017 May 11;17:52. doi: 10.1186/s12935-017-0422-x. eCollection 2017.

2.
3.

The Contribution of Cholesterol and Its Metabolites to the Pathophysiology of Breast Cancer.

Baek AE, Nelson ER.

Horm Cancer. 2016 Aug;7(4):219-28. doi: 10.1007/s12672-016-0262-5. Epub 2016 Mar 28. Review.

PMID:
27020054
4.

Re-adopting classical nuclear receptors by cholesterol metabolites.

Umetani M.

J Steroid Biochem Mol Biol. 2016 Mar;157:20-6. doi: 10.1016/j.jsbmb.2015.11.002. Epub 2015 Nov 10. Review.

5.

Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant Therapy.

Mast N, Lin JB, Pikuleva IA.

Mol Pharmacol. 2015 Sep;88(3):428-36. doi: 10.1124/mol.115.099598. Epub 2015 Jun 16.

6.

The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy.

Fan P, Maximov PY, Curpan RF, Abderrahman B, Jordan VC.

Mol Cell Endocrinol. 2015 Dec 15;418 Pt 3:245-63. doi: 10.1016/j.mce.2015.06.004. Epub 2015 Jun 5. Review.

7.

Minireview: nuclear receptor regulation of osteoclast and bone remodeling.

Jin Z, Li X, Wan Y.

Mol Endocrinol. 2015 Feb;29(2):172-86. doi: 10.1210/me.2014-1316. Epub 2014 Dec 30. Review.

8.

Cholesterol and breast cancer pathophysiology.

Nelson ER, Chang CY, McDonnell DP.

Trends Endocrinol Metab. 2014 Dec;25(12):649-55. doi: 10.1016/j.tem.2014.10.001. Epub 2014 Nov 4. Review.

9.

A screening cascade to identify ERβ ligands.

Filgueira CS, Benod C, Lou X, Gunamalai PS, Villagomez RA, Strom A, Gustafsson JÅ, Berkenstam AL, Webb P.

Nucl Recept Signal. 2014 Nov 4;12:e003. doi: 10.1621/nrs.12003. eCollection 2014.

10.

The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer.

McDonnell DP, Chang CY, Nelson ER.

Climacteric. 2014 Dec;17 Suppl 2:60-5. doi: 10.3109/13697137.2014.966949. Epub 2014 Oct 16.

11.

From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).

Wardell SE, Nelson ER, McDonnell DP.

Steroids. 2014 Nov;90:30-8. doi: 10.1016/j.steroids.2014.07.013. Epub 2014 Jul 30.

12.

Oxysterols and their cellular effectors.

Olkkonen VM, Béaslas O, Nissilä E.

Biomolecules. 2012 Feb 15;2(1):76-103. doi: 10.3390/biom2010076.

13.

27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.

Nelson ER, Wardell SE, Jasper JS, Park S, Suchindran S, Howe MK, Carver NJ, Pillai RV, Sullivan PM, Sondhi V, Umetani M, Geradts J, McDonnell DP.

Science. 2013 Nov 29;342(6162):1094-8. doi: 10.1126/science.1241908.

14.

Nuclear receptor LRH-1 induces the reproductive neuropeptide kisspeptin in the hypothalamus.

Atkin SD, Owen BM, Bookout AL, Cravo RM, Lee C, Elias CF, Elmquist JK, Kliewer SA, Mangelsdorf DJ.

Mol Endocrinol. 2013 Apr;27(4):598-605. doi: 10.1210/me.2012-1371. Epub 2013 Mar 15.

15.

The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosis.

Nelson ER, Wardell SE, McDonnell DP.

Bone. 2013 Mar;53(1):42-50. doi: 10.1016/j.bone.2012.11.011. Epub 2012 Nov 17. Review.

16.
17.

Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer.

Jones LW, Antonelli J, Masko EM, Broadwater G, Lascola CD, Fels D, Dewhirst MW, Dyck JR, Nagendran J, Flores CT, Betof AS, Nelson ER, Pollak M, Dash RC, Young ME, Freedland SJ.

J Appl Physiol (1985). 2012 Jul;113(2):263-72. doi: 10.1152/japplphysiol.01575.2011. Epub 2012 May 17.

18.

The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors.

Nelson ER, DuSell CD, Wang X, Howe MK, Evans G, Michalek RD, Umetani M, Rathmell JC, Khosla S, Gesty-Palmer D, McDonnell DP.

Endocrinology. 2011 Dec;152(12):4691-705. doi: 10.1210/en.2011-1298. Epub 2011 Sep 20.

19.

A tricistronic human adrenodoxin reductase-adrenodoxin-cytochrome P450 27A1 vector system for substrate hydroxylation in Escherichia coli.

Salamanca-Pinzón SG, Guengerich FP.

Protein Expr Purif. 2011 Oct;79(2):231-6. doi: 10.1016/j.pep.2011.05.008. Epub 2011 May 20.

20.

27-Hydroxycholesterol: the first identified endogenous SERM.

Umetani M, Shaul PW.

Trends Endocrinol Metab. 2011 Apr;22(4):130-5. doi: 10.1016/j.tem.2011.01.003. Epub 2011 Feb 23. Review.

Supplemental Content

Support Center