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microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression.

Lee H, Kim C, Kang H, Tak H, Ahn S, Yoon SK, Kuh HJ, Kim W, Lee EK.

Exp Mol Med. 2017 May 12;49(5):e327. doi: 10.1038/emm.2017.33.


Strategies for Overcoming Resistance in Tumours Harboring BRAF Mutations.

Obaid NM, Bedard K, Huang WY.

Int J Mol Sci. 2017 Mar 8;18(3). pii: E585. doi: 10.3390/ijms18030585. Review.


A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells.

Yao N, Li YJ, Lei YH, Hu N, Chen WM, Yao Z, Yu M, Liu JS, Ye WC, Zhang DM.

J Exp Clin Cancer Res. 2016 Dec 8;35(1):192.


Genomic Characterization of Metformin Hepatic Response.

Luizon MR, Eckalbar WL, Wang Y, Jones SL, Smith RP, Laurance M, Lin L, Gallins PJ, Etheridge AS, Wright F, Zhou Y, Molony C, Innocenti F, Yee SW, Giacomini KM, Ahituv N.

PLoS Genet. 2016 Nov 30;12(11):e1006449. doi: 10.1371/journal.pgen.1006449. eCollection 2016 Nov.


Regulation of cardiac hypertrophy and remodeling through the dual-specificity MAPK phosphatases (DUSPs).

Liu R, Molkentin JD.

J Mol Cell Cardiol. 2016 Dec;101:44-49. doi: 10.1016/j.yjmcc.2016.08.018. Epub 2016 Aug 27. Review.


p38 MAPK Signaling in Osteoblast Differentiation.

Rodríguez-Carballo E, Gámez B, Ventura F.

Front Cell Dev Biol. 2016 May 6;4:40. doi: 10.3389/fcell.2016.00040. eCollection 2016. Review.


Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes.

Pinilla-Macua I, Watkins SC, Sorkin A.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2122-7. doi: 10.1073/pnas.1520301113. Epub 2016 Feb 8.


The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms.

Haag T, Richter AM, Schneider MB, Jiménez AP, Dammann RH.

BMC Cancer. 2016 Feb 1;16:49. doi: 10.1186/s12885-016-2087-6.


Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1.

Farwell SL, Kanyi D, Hamel M, Slee JB, Miller EA, Cipolle MD, Lowe-Krentz LJ.

J Biol Chem. 2016 Mar 4;291(10):5342-54. doi: 10.1074/jbc.M115.681288. Epub 2016 Jan 14.


Dual Specificity Phosphatase 5, a Specific Negative Regulator of ERK Signaling, Is Induced by Serum Response Factor and Elk-1 Transcription Factor.

Buffet C, Catelli MG, Hecale-Perlemoine K, Bricaire L, Garcia C, Gallet-Dierick A, Rodriguez S, Cormier F, Groussin L.

PLoS One. 2015 Dec 21;10(12):e0145484. doi: 10.1371/journal.pone.0145484. eCollection 2015.


Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens.

Liao W, Jordaan G, Nham P, Phan RT, Pelegrini M, Sharma S.

BMC Cancer. 2015 Oct 16;15:714. doi: 10.1186/s12885-015-1708-9.


Silencing of DUSP6 gene by RNAi-mediation inhibits proliferation and growth in MDA-MB-231 breast cancer cells: an in vitro study.

Song H, Wu C, Wei C, Li D, Hua K, Song J, Xu H, Chen L, Fang L.

Int J Clin Exp Med. 2015 Jul 15;8(7):10481-90. eCollection 2015.


Context Sensitive Modeling of Cancer Drug Sensitivity.

Chen BJ, Litvin O, Ungar L, Pe'er D.

PLoS One. 2015 Aug 14;10(8):e0133850. doi: 10.1371/journal.pone.0133850. eCollection 2015.


Differential expression of FOXA1, DUSP6, and HA117 in colon segments of Hirschsprung's disease.

Luo Y, Li S, Teng Y, Wang N, Li L, Liu H, Jin X.

Int J Clin Exp Pathol. 2015 Apr 1;8(4):3979-86. eCollection 2015.


Polymorphisms in the DUSP10 gene are associated with sex-specific colorectal cancer risk in a Han population.

Duan X, Gao Y, Yang H, Feng T, Jin T, Long Y, Chen C.

Int J Clin Exp Pathol. 2015 Feb 1;8(2):2018-25. eCollection 2015.


Enhancer sequence variants and transcription-factor deregulation synergize to construct pathogenic regulatory circuits in B-cell lymphoma.

Koues OI, Kowalewski RA, Chang LW, Pyfrom SC, Schmidt JA, Luo H, Sandoval LE, Hughes TB, Bednarski JJ, Cashen AF, Payton JE, Oltz EM.

Immunity. 2015 Jan 20;42(1):186-98. doi: 10.1016/j.immuni.2014.12.021. Epub 2014 Dec 25.


Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers.

Manzano RG, Martinez-Navarro EM, Forteza J, Brugarolas A.

Int J Oncol. 2014 Dec;45(6):2250-66. doi: 10.3892/ijo.2014.2648. Epub 2014 Sep 9.


Differential subcellular and extracellular localisations of proteins required for insulin-like growth factor- and extracellular matrix-induced signalling events in breast cancer progression.

Plant HC, Kashyap AS, Manton KJ, Hollier BG, Hurst CP, Stein SR, Francis GD, Beadle GF, Upton Z, Leavesley DI.

BMC Cancer. 2014 Aug 29;14:627. doi: 10.1186/1471-2407-14-627.

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