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Items: 1 to 20 of 330

1.

Stem cell models of Alzheimer's disease: progress and challenges.

Arber C, Lovejoy C, Wray S.

Alzheimers Res Ther. 2017 Jun 13;9(1):42. doi: 10.1186/s13195-017-0268-4. Review.

2.

Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients.

Lee E, Giovanello KS, Saykin AJ, Xie F, Kong D, Wang Y, Yang L, Ibrahim JG, Doraiswamy PM, Zhu H.

Alzheimers Dement (Amst). 2017 Apr 23;8:86-95. doi: 10.1016/j.dadm.2017.04.004. eCollection 2017.

3.

Genetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans.

Wang YA, Kammenga JE, Harvey SC.

Hum Genomics. 2017 May 25;11(1):12. doi: 10.1186/s40246-017-0108-4. Review.

4.

Microglia-Synapse Pathways: Promising Therapeutic Strategy for Alzheimer's Disease.

Xie J, Wang H, Lin T, Bi B.

Biomed Res Int. 2017;2017:2986460. doi: 10.1155/2017/2986460. Epub 2017 Apr 3. Review.

5.

EXOC3L2 rs597668 variant contributes to Alzheimer's disease susceptibility in Asian population.

Wu QJ, Sun SY, Yan CJ, Cheng ZC, Yang MF, Li ZF, Cheng HW, Fang TK.

Oncotarget. 2017 Mar 21;8(12):20086-20091. doi: 10.18632/oncotarget.15380.

6.

Alzheimer's Disease: Biomarkers in the Genome, Blood, and Cerebrospinal Fluid.

Huynh RA, Mohan C.

Front Neurol. 2017 Mar 20;8:102. doi: 10.3389/fneur.2017.00102. eCollection 2017. Review.

7.

Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs.

Park SK, Ratia K, Ba M, Valencik M, Liebman SW.

Microb Cell. 2016 Jan 20;3(2):53-64. doi: 10.15698/mic2016.02.476.

8.

PRECISION MEDICINE - The Golden Gate for Detection, Treatment and Prevention of Alzheimer's Disease.

Hampel H, O'Bryant SE, Castrillo JI, Ritchie C, Rojkova K, Broich K, Benda N, Nisticò R, Frank RA, Dubois B, Escott-Price V, Lista S.

J Prev Alzheimers Dis. 2016 Dec;3(4):243-259. doi: 10.14283/jpad.2016.112. Epub 2016 Sep 6.

9.
10.

Polygenic risk scores in familial Alzheimer disease.

Tosto G, Bird TD, Tsuang D, Bennett DA, Boeve BF, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Bertlesen S, Graff-Radford NR, Medrano M, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R.

Neurology. 2017 Mar 21;88(12):1180-1186. doi: 10.1212/WNL.0000000000003734. Epub 2017 Feb 17.

PMID:
28213371
11.

Recent Progress in Alzheimer's Disease Research, Part 2: Genetics and Epidemiology.

Robinson M, Lee BY, Hane FT.

J Alzheimers Dis. 2017;57(2):317-330. doi: 10.3233/JAD-161149.

12.

Association and interaction effects of Alzheimer's disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population.

Lin E, Tsai SJ, Kuo PH, Liu YL, Yang AC, Kao CF.

Oncotarget. 2017 Apr 11;8(15):24077-24087. doi: 10.18632/oncotarget.15269.

13.

The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster.

Subramanian S, Gottschalk WK, Kim SY, Roses AD, Chiba-Falek O.

Biochim Biophys Acta. 2017 Mar;1863(3):810-816. doi: 10.1016/j.bbadis.2017.01.004. Epub 2017 Jan 6.

PMID:
28065845
14.

The effect of the top 20 Alzheimer disease risk genes on gray-matter density and FDG PET brain metabolism.

Stage E, Duran T, Risacher SL, Goukasian N, Do TM, West JD, Wilhalme H, Nho K, Phillips M, Elashoff D, Saykin AJ, Apostolova LG.

Alzheimers Dement (Amst). 2016 Dec 19;5:53-66. doi: 10.1016/j.dadm.2016.12.003. eCollection 2016.

15.

Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury.

Suárez-Calvet M, Araque Caballero MÁ, Kleinberger G, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Ewers M, Haass C; Dominantly Inherited Alzheimer Network.

Sci Transl Med. 2016 Dec 14;8(369):369ra178.

16.
17.

Performance Metrics for Selecting Single Nucleotide Polymorphisms in Late-onset Alzheimer's Disease.

Chen YC, Hsiao CJ, Jung CC, Hu HH, Chen JH, Lee WC, Chiou JM, Chen TF, Sun Y, Wen LL, Yip PK, Chu YM, Chen CJ, Yang HI.

Sci Rep. 2016 Nov 2;6:36155. doi: 10.1038/srep36155.

18.

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.

Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, Ibrahim-Verbaas CA, Choi SH, Satizabal CL, Lopez OL, Beiser A, Ikram MA, Garcia ME, Hayward C, Varga TV, Ripatti S, Franks PW, Hallmans G, Rolandsson O, Jansson JH, Porteous DJ, Salomaa V, Eiriksdottir G, Rice KM, Bellen HJ, Levy D, Uitterlinden AG, Emilsson V, Rotter JI, Aspelund T; Cohorts for Heart and Aging Research in Genomic Epidemiology consortium; Alzheimer’s Disease Genetic Consortium; Genetic and Environmental Risk in Alzheimer’s Disease consortium, O'Donnell CJ, Fitzpatrick AL, Launer LJ, Hofman A, Wang LS, Williams J, Schellenberg GD, Boerwinkle E, Psaty BM, Seshadri S, Shulman JM, Gudnason V, van Duijn CM.

PLoS Genet. 2016 Oct 20;12(10):e1006327. doi: 10.1371/journal.pgen.1006327. eCollection 2016 Oct. Erratum in: PLoS Genet. 2016 Nov 28;12 (11):e1006456.

19.

Gene expression analysis reveals the dysregulation of immune and metabolic pathways in Alzheimer's disease.

Chen J, Xie C, Zhao Y, Li Z, Xu P, Yao L.

Oncotarget. 2016 Nov 8;7(45):72469-72474. doi: 10.18632/oncotarget.12505.

20.

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases.

Allen M, Carrasquillo MM, Funk C, Heavner BD, Zou F, Younkin CS, Burgess JD, Chai HS, Crook J, Eddy JA, Li H, Logsdon B, Peters MA, Dang KK, Wang X, Serie D, Wang C, Nguyen T, Lincoln S, Malphrus K, Bisceglio G, Li M, Golde TE, Mangravite LM, Asmann Y, Price ND, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.

Sci Data. 2016 Oct 11;3:160089. doi: 10.1038/sdata.2016.89.

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