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Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.

Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9015-20. doi: 10.1073/pnas.1603883113.


Activation of SK2 channels preserves ER Ca²⁺ homeostasis and protects against ER stress-induced cell death.

Richter M, Vidovic N, Honrath B, Mahavadi P, Dodel R, Dolga AM, Culmsee C.

Cell Death Differ. 2016 May;23(5):814-27. doi: 10.1038/cdd.2015.146.


Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic Priming.

Rzechorzek NM, Connick P, Patani R, Selvaraj BT, Chandran S.

EBioMedicine. 2015 Apr 11;2(6):528-35. doi: 10.1016/j.ebiom.2015.04.004.


Endoplasmic Reticulum Stress in the Diabetic Kidney, the Good, the Bad and the Ugly.

Cunard R.

J Clin Med. 2015 Apr 20;4(4):715-40. doi: 10.3390/jcm4040715. Review.


De-repression of myelin-regulating gene expression after status epilepticus in mice lacking the C/EBP homologous protein CHOP.

Sheedy C, Mooney C, Jimenez-Mateos E, Sanz-Rodriguez A, Langa E, Mooney C, Engel T.

Int J Physiol Pathophysiol Pharmacol. 2014 Dec 15;6(4):185-98.


The endoplasmic reticulum stress and the HIF-1 signalling pathways are involved in the neuronal damage caused by chemical hypoxia.

López-Hernández B, Ceña V, Posadas I.

Br J Pharmacol. 2015 Jun;172(11):2838-51. doi: 10.1111/bph.13095.


Ischemia/reperfusion-induced CHOP expression promotes apoptosis and impairs renal function recovery: the role of acidosis and GPR4.

Dong B, Zhou H, Han C, Yao J, Xu L, Zhang M, Fu Y, Xia Q.

PLoS One. 2014 Oct 24;9(10):e110944. doi: 10.1371/journal.pone.0110944.


Cerebellar Purkinje cell p75 neurotrophin receptor and autistic behavior.

Lotta LT, Conrad K, Cory-Slechta D, Schor NF.

Transl Psychiatry. 2014 Jul 29;4:e416. doi: 10.1038/tp.2014.55. Erratum in: Transl Psychiatry. 2014;4:e476.


Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells.

Cano M, Wang L, Wan J, Barnett BP, Ebrahimi K, Qian J, Handa JT.

Free Radic Biol Med. 2014 Apr;69:1-14. doi: 10.1016/j.freeradbiomed.2014.01.004.


An enhanced integrated stress response ameliorates mutant SOD1-induced ALS.

Wang L, Popko B, Roos RP.

Hum Mol Genet. 2014 May 15;23(10):2629-38. doi: 10.1093/hmg/ddt658.


Chopping Out CHOP Chops the Fate of Neurons.

Boison D.

Epilepsy Curr. 2013 Sep;13(5):219-20. doi: 10.5698/1535-7597-13.5.219. No abstract available.


Expression of the CHOP-inducible carbonic anhydrase CAVI-b is required for BDNF-mediated protection from hypoxia.

Matthews TA, Abel A, Demme C, Sherman T, Pan PW, Halterman MW, Parkkila S, Nehrke K.

Brain Res. 2014 Jan 16;1543:28-37. doi: 10.1016/j.brainres.2013.11.018.


Mfn2 modulates the UPR and mitochondrial function via repression of PERK.

Muñoz JP, Ivanova S, Sánchez-Wandelmer J, Martínez-Cristóbal P, Noguera E, Sancho A, Díaz-Ramos A, Hernández-Alvarez MI, Sebastián D, Mauvezin C, Palacín M, Zorzano A.

EMBO J. 2013 Aug 28;32(17):2348-61. doi: 10.1038/emboj.2013.168. Erratum in: EMBO J. 2014 Jan 13;33(2):171.


Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis.

Matus S, Lopez E, Valenzuela V, Nassif M, Hetz C.

PLoS One. 2013;8(7):e66672. doi: 10.1371/journal.pone.0066672.


Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus.

Ryley Parrish R, Albertson AJ, Buckingham SC, Hablitz JJ, Mascia KL, Davis Haselden W, Lubin FD.

Neuroscience. 2013 Sep 17;248:602-19. doi: 10.1016/j.neuroscience.2013.06.029.


C/EBP homologous binding protein (CHOP) underlies neural injury in sleep apnea model.

Chou YT, Zhan G, Zhu Y, Fenik P, Panossian L, Li Y, Zhang J, Veasey S.

Sleep. 2013 Apr 1;36(4):481-92. doi: 10.5665/sleep.2528.


ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkin.

Sun X, Liu J, Crary JF, Malagelada C, Sulzer D, Greene LA, Levy OA.

J Neurosci. 2013 Feb 6;33(6):2398-407. doi: 10.1523/JNEUROSCI.2292-12.2013.


Neuronal responses to physiological stress.

Kagias K, Nehammer C, Pocock R.

Front Genet. 2012 Oct 26;3:222. doi: 10.3389/fgene.2012.00222.


Pharmacological modulation of the retinal unfolded protein response in Bardet-Biedl syndrome reduces apoptosis and preserves light detection ability.

Mockel A, Obringer C, Hakvoort TB, Seeliger M, Lamers WH, Stoetzel C, Dollfus H, Marion V.

J Biol Chem. 2012 Oct 26;287(44):37483-94. doi: 10.1074/jbc.M112.386821.


C/EBP homologous protein (CHOP) deficiency aggravates hippocampal cell apoptosis and impairs memory performance.

Chen CM, Wu CT, Chiang CK, Liao BW, Liu SH.

PLoS One. 2012;7(7):e40801. doi: 10.1371/journal.pone.0040801.

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