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Items: 1 to 20 of 39

1.

A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin.

Janssen A, Breuer GA, Brinkman EK, van der Meulen AI, Borden SV, van Steensel B, Bindra RS, LaRocque JR, Karpen GH.

Genes Dev. 2016 Jul 15;30(14):1645-57. doi: 10.1101/gad.283028.116.

PMID:
27474442
2.

Sharpening the ends for repair: mechanisms and regulation of DNA resection.

Paudyal SC, You Z.

Acta Biochim Biophys Sin (Shanghai). 2016 Jul;48(7):647-57. doi: 10.1093/abbs/gmw043. Epub 2016 May 12. Review.

PMID:
27174871
3.

Retinal pigment epithelial cell multinucleation in the aging eye - a mechanism to repair damage and maintain homoeostasis.

Chen M, Rajapakse D, Fraczek M, Luo C, Forrester JV, Xu H.

Aging Cell. 2016 Jun;15(3):436-45. doi: 10.1111/acel.12447. Epub 2016 Feb 15.

4.

Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities.

Cheruiyot A, Paudyal SC, Kim IK, Sparks M, Ellenberger T, Piwnica-Worms H, You Z.

DNA Repair (Amst). 2015 Nov;35:106-15. doi: 10.1016/j.dnarep.2015.09.021. Epub 2015 Sep 30.

PMID:
26519824
5.

Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair.

Schmidt CK, Galanty Y, Sczaniecka-Clift M, Coates J, Jhujh S, Demir M, Cornwell M, Beli P, Jackson SP.

Nat Cell Biol. 2015 Nov;17(11):1458-70. doi: 10.1038/ncb3260. Epub 2015 Oct 26.

6.

Modulation of DNA damage and repair pathways by human tumour viruses.

Hollingworth R, Grand RJ.

Viruses. 2015 May 22;7(5):2542-91. doi: 10.3390/v7052542. Review. Erratum in: Viruses. 2015 Jun;7(6):3201-3.

7.

The COP9 signalosome is vital for timely repair of DNA double-strand breaks.

Meir M, Galanty Y, Kashani L, Blank M, Khosravi R, Fernández-Ávila MJ, Cruz-García A, Star A, Shochot L, Thomas Y, Garrett LJ, Chamovitz DA, Bodine DM, Kurz T, Huertas P, Ziv Y, Shiloh Y.

Nucleic Acids Res. 2015 May 19;43(9):4517-30. doi: 10.1093/nar/gkv270. Epub 2015 Apr 8.

8.

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.

Badie S, Carlos AR, Folio C, Okamoto K, Bouwman P, Jonkers J, Tarsounas M.

EMBO J. 2015 Feb 3;34(3):410-24. doi: 10.15252/embj.201488947. Epub 2015 Jan 12. Erratum in: EMBO J. 2015 Mar 12;34(6):828.

9.

Loss of autophagy causes a synthetic lethal deficiency in DNA repair.

Liu EY, Xu N, O'Prey J, Lao LY, Joshi S, Long JS, O'Prey M, Croft DR, Beaumatin F, Baudot AD, Mrschtik M, Rosenfeldt M, Zhang Y, Gillespie DA, Ryan KM.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):773-8. doi: 10.1073/pnas.1409563112. Epub 2015 Jan 7.

10.

The Fanconi anemia ID2 complex: dueling saxes at the crossroads.

Boisvert RA, Howlett NG.

Cell Cycle. 2014;13(19):2999-3015. doi: 10.4161/15384101.2014.956475. Review.

11.

DNA end resection is needed for the repair of complex lesions in G1-phase human cells.

Averbeck NB, Ringel O, Herrlitz M, Jakob B, Durante M, Taucher-Scholz G.

Cell Cycle. 2014;13(16):2509-16. doi: 10.4161/15384101.2015.941743.

12.

CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells.

Neganova I, Tilgner K, Buskin A, Paraskevopoulou I, Atkinson SP, Peberdy D, Passos JF, Lako M.

Cell Death Dis. 2014 Nov 6;5:e1508. doi: 10.1038/cddis.2014.464.

13.

The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes.

Paull TT, Deshpande RA.

Exp Cell Res. 2014 Nov 15;329(1):139-47. doi: 10.1016/j.yexcr.2014.07.007. Epub 2014 Jul 9. Review. No abstract available.

14.

Pathways for genome integrity in G2 phase of the cell cycle.

Kousholt AN, Menzel T, Sørensen CS.

Biomolecules. 2012 Nov 30;2(4):579-607. doi: 10.3390/biom2040579. Erratum in: Biomolecules. 2013;3(1):72-4.

15.

Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection.

Makharashvili N, Tubbs AT, Yang SH, Wang H, Barton O, Zhou Y, Deshpande RA, Lee JH, Lobrich M, Sleckman BP, Wu X, Paull TT.

Mol Cell. 2014 Jun 19;54(6):1022-33. doi: 10.1016/j.molcel.2014.04.011. Epub 2014 May 15.

16.

DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells.

Oh S, Harvey A, Zimbric J, Wang Y, Nguyen T, Jackson PJ, Hendrickson EA.

DNA Repair (Amst). 2014 Sep;21:97-110. doi: 10.1016/j.dnarep.2014.04.015. Epub 2014 May 16.

17.

Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells.

Wang Z, Yin H, Lv L, Feng Y, Chen S, Liang J, Huang Y, Jiang X, Jiang H, Bukhari I, Wu L, Cooke HJ, Shi Q.

Cell Cycle. 2014;13(8):1345-56. doi: 10.4161/cc.28296. Epub 2014 Mar 4.

18.

Phosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme.

Fu Q, Chow J, Bernstein KA, Makharashvili N, Arora S, Lee CF, Person MD, Rothstein R, Paull TT.

Mol Cell Biol. 2014 Mar;34(5):778-93. doi: 10.1128/MCB.00963-13. Epub 2013 Dec 16. Erratum in: Mol Cell Biol. 2014 Nov 15;34(22):4213.

19.

CtIP is required for DNA damage-dependent induction of P21.

Liu B, Cong R, Peng B, Zhu B, Dou G, Ai H, Zhang X, Wang Z, Xu X.

Cell Cycle. 2014;13(1):90-5. doi: 10.4161/cc.26810. Epub 2013 Oct 23.

20.

ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage.

Gamper AM, Rofougaran R, Watkins SC, Greenberger JS, Beumer JH, Bakkenist CJ.

Nucleic Acids Res. 2013 Dec;41(22):10334-44. doi: 10.1093/nar/gkt833. Epub 2013 Sep 14.

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