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Items: 1 to 20 of 28


Regional and source-based patterns of [11C]-(+)-PHNO binding potential reveal concurrent alterations in dopamine D2 and D3 receptor availability in cocaine-use disorder.

Worhunsky PD, Matuskey D, Gallezot JD, Gaiser EC, Nabulsi N, Angarita GA, Calhoun VD, Malison RT, Potenza MN, Carson RE.

Neuroimage. 2017 Mar 1;148:343-351. doi: 10.1016/j.neuroimage.2017.01.045. Epub 2017 Jan 19.


Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases.

Maramai S, Gemma S, Brogi S, Campiani G, Butini S, Stark H, Brindisi M.

Front Neurosci. 2016 Oct 5;10:451. eCollection 2016. Review.


Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model.

Flagel SB, Chaudhury S, Waselus M, Kelly R, Sewani S, Clinton SM, Thompson RC, Watson SJ Jr, Akil H.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2861-70. doi: 10.1073/pnas.1520491113. Epub 2016 Apr 25.


Neuroprotective Effects of the Glutamate Transporter Activator (R)-(-)-5-methyl-1-nicotinoyl-2-pyrazoline (MS-153) following Traumatic Brain Injury in the Adult Rat.

Karklin Fontana AC, Fox DP, Zoubroulis A, Valente Mortensen O, Raghupathi R.

J Neurotrauma. 2016 Jun 1;33(11):1073-83. doi: 10.1089/neu.2015.4079. Epub 2015 Sep 24.


Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis.

Keck TM, John WS, Czoty PW, Nader MA, Newman AH.

J Med Chem. 2015 Jul 23;58(14):5361-80. doi: 10.1021/jm501512b. Epub 2015 Mar 31.


Neuronal circuitry underlying the impact of D3 receptor ligands in drug addiction.

Le Foll B, Di Ciano P.

Eur Neuropsychopharmacol. 2015 Sep;25(9):1401-9. doi: 10.1016/j.euroneuro.2014.08.017. Epub 2014 Sep 16. Review.


Performance on a strategy set shifting task in rats following adult or adolescent cocaine exposure.

Kantak KM, Barlow N, Tassin DH, Brisotti MF, Jordan CJ.

Psychopharmacology (Berl). 2014 Dec;231(23):4489-501. doi: 10.1007/s00213-014-3598-y. Epub 2014 May 7.


A shift in the role of glutamatergic signaling in the nucleus accumbens core with the development of an addicted phenotype.

Doyle SE, Ramôa C, Garber G, Newman J, Toor Z, Lynch WJ.

Biol Psychiatry. 2014 Nov 15;76(10):810-5. doi: 10.1016/j.biopsych.2014.02.005. Epub 2014 Feb 14.


Addicted to palatable foods: comparing the neurobiology of Bulimia Nervosa to that of drug addiction.

Hadad NA, Knackstedt LA.

Psychopharmacology (Berl). 2014 May;231(9):1897-912. doi: 10.1007/s00213-014-3461-1. Epub 2014 Feb 6. Review.


Transforming growth factor beta receptor 1 is increased following abstinence from cocaine self-administration, but not cocaine sensitization.

Gancarz-Kausch AM, Schroeder GL, Panganiban C, Adank D, Humby MS, Kausch MA, Clark SD, Dietz DM.

PLoS One. 2013 Dec 30;8(12):e83834. doi: 10.1371/journal.pone.0083834. eCollection 2013.


Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats.

Song R, Bi GH, Zhang HY, Yang RF, Gardner EL, Li J, Xi ZX.

Neuropharmacology. 2014 Feb;77:398-405. doi: 10.1016/j.neuropharm.2013.10.010. Epub 2013 Oct 28.


Reduction of cocaine self-administration and D3 receptor-mediated behavior by two novel dopamine D3 receptor-selective partial agonists, OS-3-106 and WW-III-55.

Cheung TH, Loriaux AL, Weber SM, Chandler KN, Lenz JD, Schaan RF, Mach RH, Luedtke RR, Neisewander JL.

J Pharmacol Exp Ther. 2013 Nov;347(2):410-23. doi: 10.1124/jpet.112.202911. Epub 2013 Sep 9.


Dopamine D3 and 5-HT1B receptor dysregulation as a result of psychostimulant intake and forced abstinence: Implications for medications development.

Neisewander JL, Cheung TH, Pentkowski NS.

Neuropharmacology. 2014 Jan;76 Pt B:301-19. doi: 10.1016/j.neuropharm.2013.08.014. Epub 2013 Aug 23. Review.


Fos expression in response to dopamine D3-preferring phenylpiperazine drugs given with and without cocaine.

Nolan BC, Liu S, Hammerslag LR, Cheung TH, Lenz J, Mach RH, Luedtke RR, Neisewander JL.

Synapse. 2013 Dec;67(12):847-55. doi: 10.1002/syn.21691. Epub 2013 Jul 17.


Dopamine Genetics and Function in Food and Substance Abuse.

Blum K, Oscar-Berman M, Barh D, Giordano J, Gold M.

J Genet Syndr Gene Ther. 2013 Feb 10;4(121). pii: 1000121.


Baseline-dependent effects of cocaine pre-exposure on impulsivity and D2/3 receptor availability in the rat striatum: possible relevance to the attention-deficit hyperactivity syndrome.

Caprioli D, Hong YT, Sawiak SJ, Ferrari V, Williamson DJ, Jupp B, Adrian Carpenter T, Aigbirhio FI, Everitt BJ, Robbins TW, Fryer TD, Dalley JW.

Neuropsychopharmacology. 2013 Jul;38(8):1460-71. doi: 10.1038/npp.2013.44. Epub 2013 Feb 11.


Effects of cocaine and withdrawal on the mouse nucleus accumbens transcriptome.

Eipper-Mains JE, Kiraly DD, Duff MO, Horowitz MJ, McManus CJ, Eipper BA, Graveley BR, Mains RE.

Genes Brain Behav. 2013 Feb;12(1):21-33. doi: 10.1111/j.1601-183X.2012.00873.x. Epub 2012 Nov 27.


Increased vulnerability to cocaine in mice lacking dopamine D3 receptors.

Song R, Zhang HY, Li X, Bi GH, Gardner EL, Xi ZX.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17675-80. doi: 10.1073/pnas.1205297109. Epub 2012 Oct 8.


Phenylpiperazine derivatives with selectivity for dopamine D3 receptors modulate cocaine self-administration in rats.

Cheung TH, Nolan BC, Hammerslag LR, Weber SM, Durbin JP, Peartree NA, Mach RH, Luedtke RR, Neisewander JL.

Neuropharmacology. 2012 Dec;63(8):1346-59. doi: 10.1016/j.neuropharm.2012.08.011. Epub 2012 Aug 31.

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