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Items: 1 to 20 of 22


PrPSc formation and clearance as determinants of prion tropism.

Shikiya RA, Langenfeld KA, Eckland TE, Trinh J, Holec SA, Mathiason CK, Kincaid AE, Bartz JC.

PLoS Pathog. 2017 Mar 29;13(3):e1006298. doi: 10.1371/journal.ppat.1006298. eCollection 2017 Mar.


Intra-host mathematical model of chronic wasting disease dynamics in deer (Odocoileus).

Holcomb KM, Galloway NL, Mathiason CK, Antolin MF.

Prion. 2016 Sep 2;10(5):377-390. Epub 2016 Aug 18.


Seeded Amplification of Chronic Wasting Disease Prions in Nasal Brushings and Recto-anal Mucosa-Associated Lymphoid Tissues from Elk by Real-Time Quaking-Induced Conversion.

Haley NJ, Siepker C, Hoon-Hanks LL, Mitchell G, Walter WD, Manca M, Monello RJ, Powers JG, Wild MA, Hoover EA, Caughey B, Richt JA.

J Clin Microbiol. 2016 Apr;54(4):1117-26. doi: 10.1128/JCM.02700-15. Epub 2016 Feb 17.


Antemortem Detection of Chronic Wasting Disease Prions in Nasal Brush Collections and Rectal Biopsy Specimens from White-Tailed Deer by Real-Time Quaking-Induced Conversion.

Haley NJ, Siepker C, Walter WD, Thomsen BV, Greenlee JJ, Lehmkuhl AD, Richt JA.

J Clin Microbiol. 2016 Apr;54(4):1108-16. doi: 10.1128/JCM.02699-15. Epub 2016 Feb 10.


Host Determinants of Prion Strain Diversity Independent of Prion Protein Genotype.

Crowell J, Hughson A, Caughey B, Bessen RA.

J Virol. 2015 Oct;89(20):10427-41. doi: 10.1128/JVI.01586-15. Epub 2015 Aug 5.


Identification of novel putative-binding proteins for cellular prion protein and a specific interaction with the STIP1 homology and U-Box-containing protein 1.

Gimenez AP, Richter LM, Atherino MC, Beirão BC, Fávaro C Jr, Costa MD, Zanata SM, Malnic B, Mercadante AF.

Prion. 2015;9(5):355-66. doi: 10.1080/19336896.2015.1075347. Epub 2015 Aug 3.


Lesion of the olfactory epithelium accelerates prion neuroinvasion and disease onset when prion replication is restricted to neurons.

Crowell J, Wiley JA, Bessen RA.

PLoS One. 2015 Mar 30;10(3):e0119863. doi: 10.1371/journal.pone.0119863. eCollection 2015.


The sheddase ADAM10 is a potent modulator of prion disease.

Altmeppen HC, Prox J, Krasemann S, Puig B, Kruszewski K, Dohler F, Bernreuther C, Hoxha A, Linsenmeier L, Sikorska B, Liberski PP, Bartsch U, Saftig P, Glatzel M.

Elife. 2015 Feb 5;4. doi: 10.7554/eLife.04260.


A test for Creutzfeldt-Jakob disease using nasal brushings.

Orrú CD, Bongianni M, Tonoli G, Ferrari S, Hughson AG, Groveman BR, Fiorini M, Pocchiari M, Monaco S, Caughey B, Zanusso G.

N Engl J Med. 2014 Aug 7;371(6):519-29. doi: 10.1056/NEJMoa1315200. Erratum in: N Engl J Med. 2014 Nov 6;371(19):1852.


Preclinical detection of variant CJD and BSE prions in blood.

Lacroux C, Comoy E, Moudjou M, Perret-Liaudet A, Lugan S, Litaise C, Simmons H, Jas-Duval C, Lantier I, Béringue V, Groschup M, Fichet G, Costes P, Streichenberger N, Lantier F, Deslys JP, Vilette D, Andréoletti O.

PLoS Pathog. 2014 Jun 12;10(6):e1004202. doi: 10.1371/journal.ppat.1004202. eCollection 2014 Jun.


Axonal and transynaptic spread of prions.

Shearin H, Bessen RA.

J Virol. 2014 Aug;88(15):8640-55. doi: 10.1128/JVI.00378-14. Epub 2014 May 21.


Intranasal inoculation of white-tailed deer (Odocoileus virginianus) with lyophilized chronic wasting disease prion particulate complexed to montmorillonite clay.

Nichols TA, Spraker TR, Rigg TD, Meyerett-Reid C, Hoover C, Michel B, Bian J, Hoover E, Gidlewski T, Balachandran A, O'Rourke K, Telling GC, Bowen R, Zabel MD, VerCauteren KC.

PLoS One. 2013 May 9;8(5):e62455. doi: 10.1371/journal.pone.0062455. Print 2013.


Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC.

Vascellari S, Orrù CD, Hughson AG, King D, Barron R, Wilham JM, Baron GS, Race B, Pani A, Caughey B.

PLoS One. 2012;7(11):e48969. doi: 10.1371/journal.pone.0048969. Epub 2012 Nov 5.


Mucosal transmission and pathogenesis of chronic wasting disease in ferrets.

Perrott MR, Sigurdson CJ, Mason GL, Hoover EA.

J Gen Virol. 2013 Feb;94(Pt 2):432-42. doi: 10.1099/vir.0.046110-0. Epub 2012 Oct 24.


Rapid transepithelial transport of prions following inhalation.

Kincaid AE, Hudson KF, Richey MW, Bartz JC.

J Virol. 2012 Dec;86(23):12731-40. doi: 10.1128/JVI.01930-12. Epub 2012 Sep 12.


Particle-size dependent effects in the Balb/c murine model of inhalational melioidosis.

Thomas RJ, Davies C, Nunez A, Hibbs S, Eastaugh L, Harding S, Jordan J, Barnes K, Oyston P, Eley S.

Front Cell Infect Microbiol. 2012 Jul 23;2:101. doi: 10.3389/fcimb.2012.00101. eCollection 2012.


Prion pathogenesis and secondary lymphoid organs (SLO): tracking the SLO spread of prions to the brain.

Mabbott NA.

Prion. 2012 Sep-Oct;6(4):322-33. doi: 10.4161/pri.20676. Epub 2012 Aug 16.


Transmission of chronic wasting disease identifies a prion strain causing cachexia and heart infection in hamsters.

Bessen RA, Robinson CJ, Seelig DM, Watschke CP, Lowe D, Shearin H, Martinka S, Babcock AM.

PLoS One. 2011;6(12):e28026. doi: 10.1371/journal.pone.0028026. Epub 2011 Dec 12.


Accelerated shedding of prions following damage to the olfactory epithelium.

Bessen RA, Wilham JM, Lowe D, Watschke CP, Shearin H, Martinka S, Caughey B, Wiley JA.

J Virol. 2012 Feb;86(3):1777-88. doi: 10.1128/JVI.06626-11. Epub 2011 Nov 30.


Prion disease blood test using immunoprecipitation and improved quaking-induced conversion.

Orrú CD, Wilham JM, Raymond LD, Kuhn F, Schroeder B, Raeber AJ, Caughey B.

MBio. 2011 May 10;2(3):e00078-11. doi: 10.1128/mBio.00078-11. Print 2011.

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