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Items: 1 to 20 of 87

1.

Histone Adduction and Its Functional Impact on Epigenetics.

Galligan JJ, Marnett LJ.

Chem Res Toxicol. 2017 Jan 17;30(1):376-387. doi: 10.1021/acs.chemrestox.6b00379.

2.

Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells.

Collinson A, Collier AJ, Morgan NP, Sienerth AR, Chandra T, Andrews S, Rugg-Gunn PJ.

Cell Rep. 2016 Dec 6;17(10):2700-2714. doi: 10.1016/j.celrep.2016.11.032.

3.

Epigenetic mechanisms drive the progression of neurofibromas to malignant peripheral nerve sheath tumors.

Suresh K, Kliot T, Piunti A, Kliot M.

Surg Neurol Int. 2016 Nov 14;7(Suppl 33):S797-S800. Review.

4.

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.

Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJ, Iorio F, Pina C, Vassiliou GS, Yusa K.

Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079.

5.

The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition.

Sashida G, Wang C, Tomioka T, Oshima M, Aoyama K, Kanai A, Mochizuki-Kashio M, Harada H, Shimoda K, Iwama A.

J Exp Med. 2016 Jul 25;213(8):1459-77. doi: 10.1084/jem.20151121.

6.

MSK1 triggers the expression of the INK4AB/ARF locus in oncogene-induced senescence.

Culerrier R, Carraz M, Mann C, Djabali M.

Mol Biol Cell. 2016 Sep 1;27(17):2726-34. doi: 10.1091/mbc.E15-11-0772.

7.

Polycomb repressive complex's evolutionary conserved function: the role of EZH2 status and cellular background.

Gall TroĊĦelj K, Novak Kujundzic R, Ugarkovic D.

Clin Epigenetics. 2016 May 27;8:55. doi: 10.1186/s13148-016-0226-1. Review.

8.

Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs.

Brien GL, Valerio DG, Armstrong SA.

Cancer Cell. 2016 Apr 11;29(4):464-76. doi: 10.1016/j.ccell.2016.03.007. Review.

PMID:
27070701
9.

Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer.

Boulding T, Wu F, McCuaig R, Dunn J, Sutton CR, Hardy K, Tu W, Bullman A, Yip D, Dahlstrom JE, Rao S.

PLoS One. 2016 Feb 9;11(2):e0148065. doi: 10.1371/journal.pone.0148065.

10.

Understanding the genetic liability to schizophrenia through the neuroepigenome.

Fullard JF, Halene TB, Giambartolomei C, Haroutunian V, Akbarian S, Roussos P.

Schizophr Res. 2016 Nov;177(1-3):115-124. doi: 10.1016/j.schres.2016.01.039. Review.

PMID:
26827128
11.

FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity.

Krishnakumar R, Chen AF, Pantovich MG, Danial M, Parchem RJ, Labosky PA, Blelloch R.

Cell Stem Cell. 2016 Jan 7;18(1):104-17. doi: 10.1016/j.stem.2015.10.003.

12.

Regulation of gene transcription by Polycomb proteins.

Aranda S, Mas G, Di Croce L.

Sci Adv. 2015 Dec 4;1(11):e1500737. doi: 10.1126/sciadv.1500737.

13.

Expression of Genes Related to Germ Cell Lineage and Pluripotency in Single Cells and Colonies of Human Adult Germ Stem Cells.

Conrad S, Azizi H, Hatami M, Kubista M, Bonin M, Hennenlotter J, Sievert KD, Skutella T.

Stem Cells Int. 2016;2016:8582526. doi: 10.1155/2016/8582526.

14.

CBP binding outside of promoters and enhancers in Drosophila melanogaster.

Philip P, Boija A, Vaid R, Churcher AM, Meyers DJ, Cole PA, Mannervik M, Stenberg P.

Epigenetics Chromatin. 2015 Nov 24;8:48. doi: 10.1186/s13072-015-0042-4. Erratum in: Epigenetics Chromatin. 2016;9(1):38.

15.

Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance.

Sun J, Shen Q, Lu H, Jiang Z, Xu W, Feng L, Li L, Wang X, Cai X, Jin H.

Oncotarget. 2015 Dec 8;6(39):41997-2007. doi: 10.18632/oncotarget.6015.

16.

The interplay of histone modifications - writers that read.

Zhang T, Cooper S, Brockdorff N.

EMBO Rep. 2015 Nov;16(11):1467-81. doi: 10.15252/embr.201540945. Review.

17.

The quest for mammalian Polycomb response elements: are we there yet?

Bauer M, Trupke J, Ringrose L.

Chromosoma. 2016 Jun;125(3):471-96. doi: 10.1007/s00412-015-0539-4. Review.

18.

Epigenetic Control of the Bone-master Runx2 Gene during Osteoblast-lineage Commitment by the Histone Demethylase JARID1B/KDM5B.

Rojas A, Aguilar R, Henriquez B, Lian JB, Stein JL, Stein GS, van Wijnen AJ, van Zundert B, Allende ML, Montecino M.

J Biol Chem. 2015 Nov 20;290(47):28329-42. doi: 10.1074/jbc.M115.657825.

19.

Regulation of Nucleosome Architecture and Factor Binding Revealed by Nuclease Footprinting of the ESC Genome.

Hainer SJ, Fazzio TG.

Cell Rep. 2015 Oct 6;13(1):61-9. doi: 10.1016/j.celrep.2015.08.071.

20.

Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response.

Halsall JA, Turan N, Wiersma M, Turner BM.

Epigenetics Chromatin. 2015 Sep 16;8:29. doi: 10.1186/s13072-015-0021-9.

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