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Items: 18


FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.

Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY, Renström F, Lin X, Ängquist LH, Huang J, Liu Z, Li Y, Asif Ali M, Xu M, Ahluwalia TS, Boer JM, Chen P, Daimon M, Eriksson J, Perola M, Friedlander Y, Gao YT, Heppe DH, Holloway JW, Houston DK, Kanoni S, Kim YM, Laaksonen MA, Jääskeläinen T, Lee NR, Lehtimäki T, Lemaitre RN, Lu W, Luben RN, Manichaikul A, Männistö S, Marques-Vidal P, Monda KL, Ngwa JS, Perusse L, van Rooij FJ, Xiang YB, Wen W, Wojczynski MK, Zhu J, Borecki IB, Bouchard C, Cai Q, Cooper C, Dedoussis GV, Deloukas P, Ferrucci L, Forouhi NG, Hansen T, Christiansen L, Hofman A, Johansson I, Jørgensen T, Karasawa S, Khaw KT, Kim MK, Kristiansson K, Li H, Lin X, Liu Y, Lohman KK, Long J, Mikkilä V, Mozaffarian D, North K, Pedersen O, Raitakari O, Rissanen H, Tuomilehto J, van der Schouw YT, Uitterlinden AG, Zillikens MC, Franco OH, Shyong Tai E, Ou Shu X, Siscovick DS, Toft U, Verschuren WM, Vollenweider P, Wareham NJ, Witteman JC, Zheng W, Ridker PM, Kang JH, Liang L, Jensen MK, Curhan GC, Pasquale LR, Hunter DJ, Mohlke KL, Uusitupa M, Cupples LA, Rankinen T, Orho-Melander M, Wang T, Chasman DI, Franks PW, Sørensen TI, Hu FB, Loos RJ, Nettleton JA, Qi L.

Hum Mol Genet. 2014 Dec 20;23(25):6961-72. doi: 10.1093/hmg/ddu411. Epub 2014 Aug 7.


Replication of 6 obesity genes in a meta-analysis of genome-wide association studies from diverse ancestries.

Tan LJ, Zhu H, He H, Wu KH, Li J, Chen XD, Zhang JG, Shen H, Tian Q, Krousel-Wood M, Papasian CJ, Bouchard C, Pérusse L, Deng HW.

PLoS One. 2014 May 30;9(5):e96149. doi: 10.1371/journal.pone.0096149. eCollection 2014.


Genetic susceptibility to type 2 diabetes and obesity: follow-up of findings from genome-wide association studies.

Basile KJ, Johnson ME, Xia Q, Grant SF.

Int J Endocrinol. 2014;2014:769671. doi: 10.1155/2014/769671. Epub 2014 Feb 25. Review.


FTO genotype, vitamin D status, and weight gain during childhood.

Lourenço BH, Qi L, Willett WC, Cardoso MA; ACTION Study Team..

Diabetes. 2014 Feb;63(2):808-14. doi: 10.2337/db13-1290. Epub 2013 Oct 15.


Obesity genomics: assessing the transferability of susceptibility loci across diverse populations.

Lu Y, Loos RJ.

Genome Med. 2013 Jun 28;5(6):55. doi: 10.1186/gm459. eCollection 2013. Review.


Genetics of obesity and type 2 diabetes in African Americans.

McCormack S, Grant SF.

J Obes. 2013;2013:396416. doi: 10.1155/2013/396416. Epub 2013 Mar 19. Review.


A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

Peters U, North KE, Sethupathy P, Buyske S, Haessler J, Jiao S, Fesinmeyer MD, Jackson RD, Kuller LH, Rajkovic A, Lim U, Cheng I, Schumacher F, Wilkens L, Li R, Monda K, Ehret G, Nguyen KD, Cooper R, Lewis CE, Leppert M, Irvin MR, Gu CC, Houston D, Buzkova P, Ritchie M, Matise TC, Le Marchand L, Hindorff LA, Crawford DC, Haiman CA, Kooperberg C.

PLoS Genet. 2013;9(1):e1003171. doi: 10.1371/journal.pgen.1003171. Epub 2013 Jan 17.


Estimation of genetic effects on BMI during adolescence in an ethnically diverse cohort: The National Longitudinal Study of Adolescent Health.

Graff M, North KE, Mohlke KL, Lange LA, Luo J, Harris KM, Young KL, Richardson AS, Lange EM, Gordon-Larsen P.

Nutr Diabetes. 2012 Sep 24;2:e47. doi: 10.1038/nutd.2012.20.


FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More?

Cheung MK, Yeo GS.

Front Endocrinol (Lausanne). 2011 Feb 22;2:4. doi: 10.3389/fendo.2011.00004. eCollection 2011.


Appetite regulation genes are associated with body mass index in black South African adolescents: a genetic association study.

Lombard Z, Crowther NJ, van der Merwe L, Pitamber P, Norris SA, Ramsay M.

BMJ Open. 2012 May 21;2(3). pii: e000873. doi: 10.1136/bmjopen-2012-000873. Print 2012.


Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

Sällman Almén M, Rask-Andersen M, Jacobsson JA, Ameur A, Kalnina I, Moschonis G, Juhlin S, Bringeland N, Hedberg LA, Ignatovica V, Chrousos GP, Manios Y, Klovins J, Marcus C, Gyllensten U, Fredriksson R, Schiöth HB.

Int J Obes (Lond). 2013 Mar;37(3):424-31. doi: 10.1038/ijo.2012.57. Epub 2012 Apr 24.


Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway.

Rask-Andersen M, Almén MS, Olausen HR, Olszewski PK, Eriksson J, Chavan RA, Levine AS, Fredriksson R, Schiöth HB.

BMC Neurosci. 2011 Nov 16;12:117. doi: 10.1186/1471-2202-12-117.


Implication of European-derived adiposity loci in African Americans.

Hester JM, Wing MR, Li J, Palmer ND, Xu J, Hicks PJ, Roh BH, Norris JM, Wagenknecht LE, Langefeld CD, Freedman BI, Bowden DW, Ng MC.

Int J Obes (Lond). 2012 Mar;36(3):465-73. doi: 10.1038/ijo.2011.131. Epub 2011 Jul 12.


Genome-wide association of BMI in African Americans.

Ng MC, Hester JM, Wing MR, Li J, Xu J, Hicks PJ, Roh BH, Lu L, Divers J, Langefeld CD, Freedman BI, Palmer ND, Bowden DW.

Obesity (Silver Spring). 2012 Mar;20(3):622-7. doi: 10.1038/oby.2011.154. Epub 2011 Jun 23.


Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.

Jacobsson JA, Almén MS, Benedict C, Hedberg LA, Michaëlsson K, Brooks S, Kullberg J, Axelsson T, Johansson L, Ahlström H, Fredriksson R, Lind L, Schiöth HB.

PLoS One. 2011;6(5):e20158. doi: 10.1371/journal.pone.0020158. Epub 2011 May 27.


Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study.

Demerath EW, Lutsey PL, Monda KL, Linda Kao WH, Bressler J, Pankow JS, North KE, Folsom AR.

Obesity (Silver Spring). 2011 Sep;19(9):1866-72. doi: 10.1038/oby.2011.131. Epub 2011 May 19.


FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans.

Nock NL, Plummer SJ, Thompson CL, Casey G, Li L.

Carcinogenesis. 2011 May;32(5):748-56. doi: 10.1093/carcin/bgr026. Epub 2011 Feb 11.


Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2011 Sep;35(9):1173-82. doi: 10.1038/ijo.2010.244. Epub 2010 Nov 23.

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