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Items: 10


Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice.

Gutknecht L, Popp S, Waider J, Sommerlandt FM, Göppner C, Post A, Reif A, van den Hove D, Strekalova T, Schmitt A, Colaςo MB, Sommer C, Palme R, Lesch KP.

Psychopharmacology (Berl). 2015 Jul;232(14):2429-41. doi: 10.1007/s00213-015-3879-0. Epub 2015 Feb 27.


Increased antidepressant sensitivity after prefrontal cortex glucocorticoid receptor gene deletion in mice.

Hussain RJ, Jacobson L.

Physiol Behav. 2015 Jan;138:113-7. doi: 10.1016/j.physbeh.2014.10.019. Epub 2014 Oct 29.


Temporal variability of glucocorticoid receptor activity is functionally important for the therapeutic action of fluoxetine in the hippocampus.

Lee MS, Kim YH, Park WS, Park OK, Kwon SH, Hong KS, Rhim H, Shim I, Morita K, Wong DL, Patel PD, Lyons DM, Schatzberg AF, Her S.

Mol Psychiatry. 2016 Feb;21(2):252-60. doi: 10.1038/mp.2014.137. Epub 2014 Oct 21.


Sensitivity of depression-like behavior to glucocorticoids and antidepressants is independent of forebrain glucocorticoid receptors.

Vincent MY, Hussain RJ, Zampi ME, Sheeran K, Solomon MB, Herman JP, Khan A, Jacobson L.

Brain Res. 2013 Aug 7;1525:1-15. doi: 10.1016/j.brainres.2013.05.031. Epub 2013 May 28.


Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour.

Lesch KP, Araragi N, Waider J, van den Hove D, Gutknecht L.

Philos Trans R Soc Lond B Biol Sci. 2012 Sep 5;367(1601):2426-43. doi: 10.1098/rstb.2012.0039. Review.


Lack of elevations in glucocorticoids correlates with dysphoria-like behavior after repeated social defeat.

Bowens N, Heydendael W, Bhatnagar S, Jacobson L.

Physiol Behav. 2012 Feb 28;105(4):958-65. doi: 10.1016/j.physbeh.2011.10.032. Epub 2011 Nov 12.


Chronic non-invasive corticosterone administration abolishes the diurnal pattern of tph2 expression.

Donner NC, Montoya CD, Lukkes JL, Lowry CA.

Psychoneuroendocrinology. 2012 May;37(5):645-61. doi: 10.1016/j.psyneuen.2011.08.008. Epub 2011 Sep 15.


Stress risk factors and stress-related pathology: neuroplasticity, epigenetics and endophenotypes.

Radley JJ, Kabbaj M, Jacobson L, Heydendael W, Yehuda R, Herman JP.

Stress. 2011 Sep;14(5):481-97. doi: 10.3109/10253890.2011.604751. Review.


Plasticity of presynaptic and postsynaptic serotonin 1A receptors in an animal model of epilepsy-associated depression.

Pineda EA, Hensler JG, Sankar R, Shin D, Burke TF, Mazarati AM.

Neuropsychopharmacology. 2011 May;36(6):1305-16. doi: 10.1038/npp.2011.18. Epub 2011 Feb 23.

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