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Items: 16


Inhibition of the mevalonate pathway augments the activity of pitavastatin against ovarian cancer cells.

Abdullah MI, Abed MN, Richardson A.

Sci Rep. 2017 Aug 14;7(1):8090. doi: 10.1038/s41598-017-08649-9.


Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.

de Wolf E, Abdullah MI, Jones SM, Menezes K, Moss DM, Drijfhout FP, Hart SR, Hoskins C, Stronach EA, Richardson A.

Sci Rep. 2017 Jul 14;7(1):5410. doi: 10.1038/s41598-017-05595-4.


Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study.

Gray RT, Loughrey MB, Bankhead P, Cardwell CR, McQuaid S, O'Neill RF, Arthur K, Bingham V, McGready C, Gavin AT, James JA, Hamilton PW, Salto-Tellez M, Murray LJ, Coleman HG.

Br J Cancer. 2017 Jun 6;116(12):1652-1659. doi: 10.1038/bjc.2017.139. Epub 2017 May 18.


Distinct cholesterogenic and lipidogenic gene expression patterns in ovarian cancer - a new pool of biomarkers.

Pampalakis G, Politi AL, Papanastasiou A, Sotiropoulou G.

Genes Cancer. 2015 Nov;6(11-12):472-9.


Fractal analysis and the diagnostic usefulness of silver staining nucleolar organizer regions in prostate adenocarcinoma.

Stepan A, Simionescu C, Pirici D, Ciurea R, Margaritescu C.

Anal Cell Pathol (Amst). 2015;2015:250265. doi: 10.1155/2015/250265. Epub 2015 Aug 20.


Multi-dimensional TOF-SIMS analysis for effective profiling of disease-related ions from the tissue surface.

Park JW, Jeong H, Kang B, Kim SJ, Park SY, Kang S, Kim HK, Choi JS, Hwang D, Lee TG.

Sci Rep. 2015 Jun 5;5:11077. doi: 10.1038/srep11077.


HMG-CoA reductase expression in primary colorectal cancer correlates with favourable clinicopathological characteristics and an improved clinical outcome.

Bengtsson E, Nerjovaj P, Wangefjord S, Nodin B, Eberhard J, Uhlén M, Borgquist S, Jirström K.

Diagn Pathol. 2014 Apr 7;9:78. doi: 10.1186/1746-1596-9-78.


Digital pathology and image analysis augment biospecimen annotation and biobank quality assurance harmonization.

Wei BR, Simpson RM.

Clin Biochem. 2014 Mar;47(4-5):274-9. doi: 10.1016/j.clinbiochem.2013.12.008. Epub 2013 Dec 18.


Investigation into diagnostic agreement using automated computer-assisted histopathology pattern recognition image analysis.

Webster JD, Michalowski AM, Dwyer JE, Corps KN, Wei BR, Juopperi T, Hoover SB, Simpson RM.

J Pathol Inform. 2012;3:18. doi: 10.4103/2153-3539.95130. Epub 2012 Apr 18.


The G protein-coupled estrogen receptor 1 (GPER/GPR30) does not predict survival in patients with ovarian cancer.

Kolkova Z, Casslén V, Henic E, Ahmadi S, Ehinger A, Jirström K, Casslén B.

J Ovarian Res. 2012 Mar 18;5:9. doi: 10.1186/1757-2215-5-9.


A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment.

Kulbe H, Chakravarty P, Leinster DA, Charles KA, Kwong J, Thompson RG, Coward JI, Schioppa T, Robinson SC, Gallagher WM, Galletta L; Australian Ovarian Cancer Study Group, Salako MA, Smyth JF, Hagemann T, Brennan DJ, Bowtell DD, Balkwill FR.

Cancer Res. 2012 Jan 1;72(1):66-75. doi: 10.1158/0008-5472.CAN-11-2178. Epub 2011 Nov 7.


Interleukin-6 as a therapeutic target in human ovarian cancer.

Coward J, Kulbe H, Chakravarty P, Leader D, Vassileva V, Leinster DA, Thompson R, Schioppa T, Nemeth J, Vermeulen J, Singh N, Avril N, Cummings J, Rexhepaj E, Jirström K, Gallagher WM, Brennan DJ, McNeish IA, Balkwill FR.

Clin Cancer Res. 2011 Sep 15;17(18):6083-96. doi: 10.1158/1078-0432.CCR-11-0945. Epub 2011 Jul 27.


Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen.

Brennan DJ, Laursen H, O'Connor DP, Borgquist S, Uhlen M, Gallagher WM, Pontén F, Millikan RC, Rydén L, Jirström K.

Breast Cancer Res. 2011 Jan 31;13(1):R12. doi: 10.1186/bcr2820.


Dysregulation of the mevalonate pathway promotes transformation.

Clendening JW, Pandyra A, Boutros PC, El Ghamrasni S, Khosravi F, Trentin GA, Martirosyan A, Hakem A, Hakem R, Jurisica I, Penn LZ.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15051-6. doi: 10.1073/pnas.0910258107. Epub 2010 Aug 9.

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