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Items: 1 to 20 of 26


Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model.

Lee-Barthel A, Baar K, West DWD.

J Vis Exp. 2017 Jun 11;(124). doi: 10.3791/55339.


Fell Muir Lecture: Collagen fibril formation in vitro and in vivo.

Kadler KE.

Int J Exp Pathol. 2017 Feb;98(1):4-16. doi: 10.1111/iep.12224. Epub 2017 May 16. Review.


Minimizing Injury and Maximizing Return to Play: Lessons from Engineered Ligaments.

Baar K.

Sports Med. 2017 Mar;47(Suppl 1):5-11. doi: 10.1007/s40279-017-0719-x. Review.


Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern.

Eliasson P, Svensson RB, Giannopoulos A, Eismark C, Kjær M, Schjerling P, Heinemeier KM.

PLoS One. 2017 Mar 6;12(3):e0172797. doi: 10.1371/journal.pone.0172797. eCollection 2017.


Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis.

Shaw G, Lee-Barthel A, Ross ML, Wang B, Baar K.

Am J Clin Nutr. 2017 Jan;105(1):136-143. doi: 10.3945/ajcn.116.138594. Epub 2016 Nov 16.


EGR1 Regulates Transcription Downstream of Mechanical Signals during Tendon Formation and Healing.

Gaut L, Robert N, Delalande A, Bonnin MA, Pichon C, Duprez D.

PLoS One. 2016 Nov 7;11(11):e0166237. doi: 10.1371/journal.pone.0166237. eCollection 2016.


Pleiotropic roles of the matricellular protein Sparc in tendon maturation and ageing.

Gehwolf R, Wagner A, Lehner C, Bradshaw AD, Scharler C, Niestrawska JA, Holzapfel GA, Bauer HC, Tempfer H, Traweger A.

Sci Rep. 2016 Sep 2;6:32635. doi: 10.1038/srep32635.


Proteomic differences between native and tissue-engineered tendon and ligament.

Kharaz YA, Tew SR, Peffers M, Canty-Laird EG, Comerford E.

Proteomics. 2016 May;16(10):1547-56. doi: 10.1002/pmic.201500459.


Collagen network strengthening following cyclic tensile loading.

Susilo ME, Paten JA, Sander EA, Nguyen TD, Ruberti JW.

Interface Focus. 2016 Feb 6;6(1):20150088. doi: 10.1098/rsfs.2015.0088. Erratum in: Interface Focus. 2016 Jun 6;6(3):20160020.


The exercise-induced biochemical milieu enhances collagen content and tensile strength of engineered ligaments.

West DW, Lee-Barthel A, McIntyre T, Shamim B, Lee CA, Baar K.

J Physiol. 2015 Oct 15;593(20):4665-75. doi: 10.1113/JP270737. Epub 2015 Sep 14.


Lysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon Cells.

Herchenhan A, Uhlenbrock F, Eliasson P, Weis M, Eyre D, Kadler KE, Magnusson SP, Kjaer M.

J Biol Chem. 2015 Jun 26;290(26):16440-50. doi: 10.1074/jbc.M115.641670. Epub 2015 May 15.


Exploiting cell-mediated contraction and adhesion to structure tissues in vitro.

Wudebwe UN, Bannerman A, Goldberg-Oppenheimer P, Paxton JZ, Williams RL, Grover LM.

Philos Trans R Soc Lond B Biol Sci. 2015 Feb 5;370(1661):20140200. doi: 10.1098/rstb.2014.0200.


Arhgap28 is a RhoGAP that inactivates RhoA and downregulates stress fibers.

Yeung CY, Taylor SH, Garva R, Holmes DF, Zeef LA, Soininen R, Boot-Handford RP, Kadler KE.

PLoS One. 2014 Sep 11;9(9):e107036. doi: 10.1371/journal.pone.0107036. eCollection 2014.


Tendon proper- and peritenon-derived progenitor cells have unique tenogenic properties.

Mienaltowski MJ, Adams SM, Birk DE.

Stem Cell Res Ther. 2014 Jul 8;5(4):86. doi: 10.1186/scrt475.


Mesenchymal stem cell response to growth factor treatment and low oxygen tension in 3-dimensional construct environment.

Durant TJ, Dyment N, McCarthy MB, Cote MP, Arciero RA, Mazzocca AD, Rowe D.

Muscles Ligaments Tendons J. 2014 May 8;4(1):46-51. eCollection 2014 Jan.


Gremlin-2 is a BMP antagonist that is regulated by the circadian clock.

Yeung CY, Gossan N, Lu Y, Hughes A, Hensman JJ, Bayer ML, Kjær M, Kadler KE, Meng QJ.

Sci Rep. 2014 Jun 5;4:5183. doi: 10.1038/srep05183.


3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling.

Pingel J, Lu Y, Starborg T, Fredberg U, Langberg H, Nedergaard A, Weis M, Eyre D, Kjaer M, Kadler KE.

J Anat. 2014 May;224(5):548-55. doi: 10.1111/joa.12164. Epub 2014 Feb 9.


Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype.

Bayer ML, Schjerling P, Herchenhan A, Zeltz C, Heinemeier KM, Christensen L, Krogsgaard M, Gullberg D, Kjaer M.

PLoS One. 2014 Jan 21;9(1):e86078. doi: 10.1371/journal.pone.0086078. eCollection 2014.


Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in humans and mice.

Zou Y, Zwolanek D, Izu Y, Gandhy S, Schreiber G, Brockmann K, Devoto M, Tian Z, Hu Y, Veit G, Meier M, Stetefeld J, Hicks D, Straub V, Voermans NC, Birk DE, Barton ER, Koch M, Bönnemann CG.

Hum Mol Genet. 2014 May 1;23(9):2339-52. doi: 10.1093/hmg/ddt627. Epub 2013 Dec 11.


Tendon and ligament regeneration and repair: clinical relevance and developmental paradigm.

Yang G, Rothrauff BB, Tuan RS.

Birth Defects Res C Embryo Today. 2013 Sep;99(3):203-222. doi: 10.1002/bdrc.21041. Review.

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