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Items: 1 to 20 of 167


The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer.

Yan S, Frank D, Son J, Hannan KM, Hannan RD, Chan KT, Pearson RB, Sanij E.

Int J Mol Sci. 2017 Jan 20;18(1). pii: E210. doi: 10.3390/ijms18010210. Review.


Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma.

Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV.

J Biol Chem. 2016 Dec 16;291(51):26241-26251.


Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.

Hoang CQ, Hale MA, Azevedo-Pouly AC, Elsässer HP, Deering TG, Willet SG, Pan FC, Magnuson MA, Wright CV, Swift GH, MacDonald RJ.

Mol Cell Biol. 2016 Nov 28;36(24):3033-3047.


Structure-function insights reveal the human ribosome as a cancer target for antibiotics.

Myasnikov AG, Kundhavai Natchiar S, Nebout M, Hazemann I, Imbert V, Khatter H, Peyron JF, Klaholz BP.

Nat Commun. 2016 Sep 26;7:12856. doi: 10.1038/ncomms12856.


Human AATF/Che-1 forms a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis.

Bammert L, Jonas S, Ungricht R, Kutay U.

Nucleic Acids Res. 2016 Nov 16;44(20):9803-9820.


The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth.

Bai D, Zhang J, Li T, Hang R, Liu Y, Tian Y, Huang D, Qu L, Cao X, Ji J, Zheng X.

Nat Commun. 2016 Aug 1;7:12310. doi: 10.1038/ncomms12310.


Trisomy 21 consistently activates the interferon response.

Sullivan KD, Lewis HC, Hill AA, Pandey A, Jackson LP, Cabral JM, Smith KP, Liggett LA, Gomez EB, Galbraith MD, DeGregori J, Espinosa JM.

Elife. 2016 Jul 29;5. pii: e16220. doi: 10.7554/eLife.16220.


Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer.

Kim DW, Wu N, Kim YC, Cheng PF, Basom R, Kim D, Dunn CT, Lee AY, Kim K, Lee CS, Singh A, Gazdar AF, Harris CR, Eisenman RN, Park KS, MacPherson D.

Genes Dev. 2016 Jun 1;30(11):1289-99. doi: 10.1101/gad.279307.116.


Ribosome Biogenesis is Necessary for Skeletal Muscle Hypertrophy.

Wen Y, Alimov AP, McCarthy JJ.

Exerc Sport Sci Rev. 2016 Jul;44(3):110-5. doi: 10.1249/JES.0000000000000082. No abstract available.


Nuclear Matrix Protein 4 Is a Novel Regulator of Ribosome Biogenesis and Controls the Unfolded Protein Response via Repression of Gadd34 Expression.

Young SK, Shao Y, Bidwell JP, Wek RC.

J Biol Chem. 2016 Jun 24;291(26):13780-8. doi: 10.1074/jbc.M116.729830.


The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation.

Vučićević D, Gehre M, Dhamija S, Friis-Hansen L, Meierhofer D, Sauer S, Ørom UA.

Oncotarget. 2016 Jun 7;7(23):33934-47. doi: 10.18632/oncotarget.8985.


The Dynamic Regulatory Genome of Capsaspora and the Origin of Animal Multicellularity.

Sebé-Pedrós A, Ballaré C, Parra-Acero H, Chiva C, Tena JJ, Sabidó E, Gómez-Skarmeta JL, Di Croce L, Ruiz-Trillo I.

Cell. 2016 May 19;165(5):1224-37. doi: 10.1016/j.cell.2016.03.034.


Addiction to Runx1 is partially attenuated by loss of p53 in the Eµ-Myc lymphoma model.

Borland G, Kilbey A, Hay J, Gilroy K, Terry A, Mackay N, Bell M, McDonald A, Mills K, Cameron E, Neil JC.

Oncotarget. 2016 Apr 26;7(17):22973-87. doi: 10.18632/oncotarget.8554.


Single-cell RNA-seq reveals activation of unique gene groups as a consequence of stem cell-parenchymal cell fusion.

Freeman BT, Jung JP, Ogle BM.

Sci Rep. 2016 Mar 21;6:23270. doi: 10.1038/srep23270.


Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer.

Zhang D, Park D, Zhong Y, Lu Y, Rycaj K, Gong S, Chen X, Liu X, Chao HP, Whitney P, Calhoun-Davis T, Takata Y, Shen J, Iyer VR, Tang DG.

Nat Commun. 2016 Feb 29;7:10798. doi: 10.1038/ncomms10798.


The Interplay between Myc and CTP Synthase in Drosophila.

Aughey GN, Grice SJ, Liu JL.

PLoS Genet. 2016 Feb 18;12(2):e1005867. doi: 10.1371/journal.pgen.1005867.


Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma.

Bassiri H, Benavides A, Haber M, Gilmour SK, Norris MD, Hogarty MD.

Transl Pediatr. 2015 Jul;4(3):226-38. doi: 10.3978/j.issn.2224-4336.2015.04.06. Review.


Methylthioadenosine (MTA) Regulates Liver Cells Proteome and Methylproteome: Implications in Liver Biology and Disease.

Bigaud E, Corrales FJ.

Mol Cell Proteomics. 2016 May;15(5):1498-510. doi: 10.1074/mcp.M115.055772.


Expression of Ribosomal RNA and Protein Genes in Human Embryonic Stem Cells Is Associated With the Activating H3K4me3 Histone Mark.

Zaidi SK, Boyd JR, Grandy RA, Medina R, Lian JB, Stein GS, Stein JL.

J Cell Physiol. 2016 Sep;231(9):2007-13. doi: 10.1002/jcp.25309.

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