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Items: 1 to 20 of 95

1.

The complexity of TRIM28 contribution to cancer.

Czerwińska P, Mazurek S, Wiznerowicz M.

J Biomed Sci. 2017 Aug 29;24(1):63. doi: 10.1186/s12929-017-0374-4. Review.

2.

SUMO, a small, but powerful, regulator of double-strand break repair.

Garvin AJ, Morris JR.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731). pii: 20160281. doi: 10.1098/rstb.2016.0281. Review.

PMID:
28847818
3.

C2H2 Zinc Finger Proteins: The Largest but Poorly Explored Family of Higher Eukaryotic Transcription Factors.

Fedotova AA, Bonchuk AN, Mogila VA, Georgiev PG.

Acta Naturae. 2017 Apr-Jun;9(2):47-58.

4.

CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation.

Stover JD, Farhang N, Berrett KC, Gertz J, Lawrence B, Bowles RD.

Mol Ther. 2017 Sep 6;25(9):2014-2027. doi: 10.1016/j.ymthe.2017.06.010. Epub 2017 Jul 1.

PMID:
28676344
5.

A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation.

Smole A, Lainšček D, Bezeljak U, Horvat S, Jerala R.

Mol Ther. 2017 Jan 4;25(1):102-119. doi: 10.1016/j.ymthe.2016.10.005. Epub 2017 Jan 4.

PMID:
28129106
6.

CRISPR-Mediated Epigenome Editing.

Enríquez P.

Yale J Biol Med. 2016 Dec 23;89(4):471-486. eCollection 2016 Dec. Review.

7.

Editing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and Plasticity.

Yang MG, West AE.

Yale J Biol Med. 2016 Dec 23;89(4):457-470. eCollection 2016 Dec. Review.

8.

Epigenetic Editing: On the Verge of Reprogramming Gene Expression at Will.

Cano-Rodriguez D, Rots MG.

Curr Genet Med Rep. 2016;4(4):170-179. Epub 2016 Oct 1. Review.

9.

Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing.

Amabile A, Migliara A, Capasso P, Biffi M, Cittaro D, Naldini L, Lombardo A.

Cell. 2016 Sep 22;167(1):219-232.e14. doi: 10.1016/j.cell.2016.09.006.

10.

The Transcriptional Repressive Activity of KRAB Zinc Finger Proteins Does Not Correlate with Their Ability to Recruit TRIM28.

Murphy KE, Shylo NA, Alexander KA, Churchill AJ, Copperman C, García-García MJ.

PLoS One. 2016 Sep 22;11(9):e0163555. doi: 10.1371/journal.pone.0163555. eCollection 2016.

11.

Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice.

Agustín-Pavón C, Mielcarek M, Garriga-Canut M, Isalan M.

Mol Neurodegener. 2016 Sep 6;11(1):64. doi: 10.1186/s13024-016-0128-x.

12.

The epigenome: the next substrate for engineering.

Park M, Keung AJ, Khalil AS.

Genome Biol. 2016 Aug 31;17(1):183. doi: 10.1186/s13059-016-1046-5. Review.

13.

Measles Virus Matrix Protein Inhibits Host Cell Transcription.

Yu X, Shahriari S, Li HM, Ghildyal R.

PLoS One. 2016 Aug 23;11(8):e0161360. doi: 10.1371/journal.pone.0161360. eCollection 2016.

14.

Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression.

Radzisheuskaya A, Shlyueva D, Müller I, Helin K.

Nucleic Acids Res. 2016 Oct 14;44(18):e141. Epub 2016 Jun 28.

15.

Probing the impact of chromatin conformation on genome editing tools.

Chen X, Rinsma M, Janssen JM, Liu J, Maggio I, Gonçalves MA.

Nucleic Acids Res. 2016 Jul 27;44(13):6482-92. doi: 10.1093/nar/gkw524. Epub 2016 Jun 8.

16.

Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation.

Do C, Lang CF, Lin J, Darbary H, Krupska I, Gaba A, Petukhova L, Vonsattel JP, Gallagher MP, Goland RS, Clynes RA, Dwork A, Kral JG, Monk C, Christiano AM, Tycko B.

Am J Hum Genet. 2016 May 5;98(5):934-955. doi: 10.1016/j.ajhg.2016.03.027.

17.

Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions.

Stojic L, Niemczyk M, Orjalo A, Ito Y, Ruijter AE, Uribe-Lewis S, Joseph N, Weston S, Menon S, Odom DT, Rinn J, Gergely F, Murrell A.

Nat Commun. 2016 Feb 2;7:10406. doi: 10.1038/ncomms10406.

18.

Editing the epigenome: technologies for programmable transcription and epigenetic modulation.

Thakore PI, Black JB, Hilton IB, Gersbach CA.

Nat Methods. 2016 Feb;13(2):127-37. doi: 10.1038/nmeth.3733. Review.

19.

Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis.

Martínez-Iglesias OA, Alonso-Merino E, Gómez-Rey S, Velasco-Martín JP, Martín Orozco R, Luengo E, García Martín R, Ibáñez de Cáceres I, Fernández AF, Fraga MF, González-Peramato P, Varona C, Palacios J, Regadera J, Aranda A.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E328-37. doi: 10.1073/pnas.1520469113. Epub 2016 Jan 4.

20.

H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes.

Becker JS, Nicetto D, Zaret KS.

Trends Genet. 2016 Jan;32(1):29-41. doi: 10.1016/j.tig.2015.11.001. Epub 2015 Dec 8. Review.

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