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Items: 1 to 20 of 26


Perturbations in the Replication Program Contribute to Genomic Instability in Cancer.

Blumenfeld B, Ben-Zimra M, Simon I.

Int J Mol Sci. 2017 May 25;18(6). pii: E1138. doi: 10.3390/ijms18061138. Review.


Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.

Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4442-E4451. doi: 10.1073/pnas.1618714114. Epub 2017 Apr 17.


Checkpoint-Independent Regulation of Origin Firing by Mrc1 through Interaction with Hsk1 Kinase.

Matsumoto S, Kanoh Y, Shimmoto M, Hayano M, Ueda K, Fukatsu R, Kakusho N, Masai H.

Mol Cell Biol. 2017 Mar 17;37(7). pii: e00355-16. doi: 10.1128/MCB.00355-16. Print 2017 Apr 1.


SIR2 suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences.

Foss EJ, Lao U, Dalrymple E, Adrianse RL, Loe T, Bedalov A.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):552-557. doi: 10.1073/pnas.1614781114. Epub 2017 Jan 3.


Model-based analysis of DNA replication profiles: predicting replication fork velocity and initiation rate by profiling free-cycling cells.

Gispan A, Carmi M, Barkai N.

Genome Res. 2017 Feb;27(2):310-319. doi: 10.1101/gr.205849.116. Epub 2016 Dec 27.


A role for Rtt109 in buffering gene-dosage imbalance during DNA replication.

Voichek Y, Bar-Ziv R, Barkai N.

Nucleus. 2016 Jul 3;7(4):375-81. doi: 10.1080/19491034.2016.1216743. Review.


The Genomic Landscape of Position Effects on Protein Expression Level and Noise in Yeast.

Chen X, Zhang J.

Cell Syst. 2016 May 25;2(5):347-54. doi: 10.1016/j.cels.2016.03.009. Epub 2016 May 12.


Nascent RNA folding mitigates transcription-associated mutagenesis.

Chen X, Yang JR, Zhang J.

Genome Res. 2016 Jan;26(1):50-9. doi: 10.1101/gr.195164.115. Epub 2015 Oct 30.


Replication timing is regulated by the number of MCMs loaded at origins.

Das SP, Borrman T, Liu VW, Yang SC, Bechhoefer J, Rhind N.

Genome Res. 2015 Dec;25(12):1886-92. doi: 10.1101/gr.195305.115. Epub 2015 Sep 10. Erratum in: Genome Res. 2016 Dec;26(12 ):1761.


Detecting ATM-dependent chromatin modification in DNA damage response.

Udayakumar D, Horikoshi N, Mishra L, Hunt C, Pandita TK.

Methods Mol Biol. 2015;1288:317-36. doi: 10.1007/978-1-4939-2474-5_18.


Systematic identification of cell size regulators in budding yeast.

Soifer I, Barkai N.

Mol Syst Biol. 2014 Nov 19;10:761. doi: 10.15252/msb.20145345.


Checkpoint-independent scaling of the Saccharomyces cerevisiae DNA replication program.

Gispan A, Carmi M, Barkai N.

BMC Biol. 2014 Oct 7;12:79. doi: 10.1186/s12915-014-0079-z.


Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups.

Rubinstein L, Ungar L, Harari Y, Babin V, Ben-Aroya S, Merenyi G, Marjavaara L, Chabes A, Kupiec M.

Nucleic Acids Res. 2014 Jun;42(10):6314-25. doi: 10.1093/nar/gku267. Epub 2014 Apr 11.


The dynamics of genome replication using deep sequencing.

Müller CA, Hawkins M, Retkute R, Malla S, Wilson R, Blythe MJ, Nakato R, Komata M, Shirahige K, de Moura AP, Nieduszynski CA.

Nucleic Acids Res. 2014 Jan;42(1):e3. doi: 10.1093/nar/gkt878. Epub 2013 Oct 1.


Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements.

Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H.

PLoS Genet. 2013;9(8):e1003670. doi: 10.1371/journal.pgen.1003670. Epub 2013 Aug 1. Erratum in: PLoS Genet. 2016 Aug;12(8):e1006302.


DNA replication timing.

Rhind N, Gilbert DM.

Cold Spring Harb Perspect Biol. 2013 Aug 1;5(8):a010132. doi: 10.1101/cshperspect.a010132. Review.


DNA replication stress-induced loss of reproductive capacity in S. cerevisiae and its inhibition by caloric restriction.

Weinberger M, Sampaio-Marques B, Ludovico P, Burhans WC.

Cell Cycle. 2013 Apr 15;12(8):1189-200. doi: 10.4161/cc.24232. Epub 2013 Mar 21.


Differential relationship of DNA replication timing to different forms of human mutation and variation.

Koren A, Polak P, Nemesh J, Michaelson JJ, Sebat J, Sunyaev SR, McCarroll SA.

Am J Hum Genet. 2012 Dec 7;91(6):1033-40. doi: 10.1016/j.ajhg.2012.10.018. Epub 2012 Nov 21.


Mathematical modeling of genome replication.

Retkute R, Nieduszynski CA, de Moura A.

Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Sep;86(3 Pt 1):031916. Epub 2012 Sep 17.


Conservation of replication timing reveals global and local regulation of replication origin activity.

Müller CA, Nieduszynski CA.

Genome Res. 2012 Oct;22(10):1953-62. doi: 10.1101/gr.139477.112. Epub 2012 Jul 5.

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