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Items: 1 to 20 of 74

1.

HIV integration sites and implications for maintenance of the reservoir.

Symons J, Cameron PU, Lewin SR.

Curr Opin HIV AIDS. 2018 Mar;13(2):152-159. doi: 10.1097/COH.0000000000000438.

PMID:
29206656
2.

Interactions between Retroviruses and the Host Cell Genome.

Poletti V, Mavilio F.

Mol Ther Methods Clin Dev. 2017 Oct 5;8:31-41. doi: 10.1016/j.omtm.2017.10.001. eCollection 2018 Mar 16. Review.

3.

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis.

El Ashkar S, Schwaller J, Pieters T, Goossens S, Demeulemeester J, Christ F, Van Belle S, Juge S, Boeckx N, Engelman A, Van Vlierberghe P, Debyser Z, De Rijck J.

Blood. 2018 Jan 4;131(1):95-107. doi: 10.1182/blood-2017-05-786962. Epub 2017 Oct 30.

4.

Engineering Next-Generation BET-Independent MLV Vectors for Safer Gene Therapy.

El Ashkar S, Van Looveren D, Schenk F, Vranckx LS, Demeulemeester J, De Rijck J, Debyser Z, Modlich U, Gijsbers R.

Mol Ther Nucleic Acids. 2017 Jun 16;7:231-245. doi: 10.1016/j.omtn.2017.04.002. Epub 2017 Apr 12.

5.

Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy.

Browning DL, Trobridge GD.

Biomedicines. 2016 Mar;4(1). pii: 4. doi: 10.3390/biomedicines4010004. Epub 2016 Feb 2.

6.

INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes.

Sherman E, Nobles C, Berry CC, Six E, Wu Y, Dryga A, Malani N, Male F, Reddy S, Bailey A, Bittinger K, Everett JK, Caccavelli L, Drake MJ, Bates P, Hacein-Bey-Abina S, Cavazzana M, Bushman FD.

Mol Ther Methods Clin Dev. 2016 Dec 18;4:39-49. doi: 10.1016/j.omtm.2016.11.002. eCollection 2017 Mar 17.

7.

Insight into HIV-2 latency may disclose strategies for a cure for HIV-1 infection.

Saleh S, Vranckx L, Gijsbers R, Christ F, Debyser Z.

J Virus Erad. 2017 Jan 1;3(1):7-14.

8.

Retargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-oncogenes.

Hocum JD, Linde I, Rae DT, Collins CP, Matern LK, Trobridge GD.

Sci Rep. 2016 Nov 4;6:36610. doi: 10.1038/srep36610.

9.

Towards a Safer, More Randomized Lentiviral Vector Integration Profile Exploring Artificial LEDGF Chimeras.

Vranckx LS, Demeulemeester J, Debyser Z, Gijsbers R.

PLoS One. 2016 Oct 27;11(10):e0164167. doi: 10.1371/journal.pone.0164167. eCollection 2016.

10.

Development of nanostars as a biocompatible tumor contrast agent: toward in vivo SERS imaging.

D'Hollander A, Mathieu E, Jans H, Vande Velde G, Stakenborg T, Van Dorpe P, Himmelreich U, Lagae L.

Int J Nanomedicine. 2016 Aug 4;11:3703-14. doi: 10.2147/IJN.S91340. eCollection 2016.

11.

Retroviral vector interactions with hematopoietic cells.

Everson EM, Trobridge GD.

Curr Opin Virol. 2016 Dec;21:41-46. doi: 10.1016/j.coviro.2016.07.010. Epub 2016 Aug 10. Review.

12.

LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV.

Vranckx LS, Demeulemeester J, Saleh S, Boll A, Vansant G, Schrijvers R, Weydert C, Battivelli E, Verdin E, Cereseto A, Christ F, Gijsbers R, Debyser Z.

EBioMedicine. 2016 Jun;8:248-264. doi: 10.1016/j.ebiom.2016.04.039. Epub 2016 May 13.

13.

Targeted, homology-driven gene insertion in stem cells by ZFN-loaded 'all-in-one' lentiviral vectors.

Cai Y, Laustsen A, Zhou Y, Sun C, Anderson MV, Li S, Uldbjerg N, Luo Y, Jakobsen MR, Mikkelsen JG.

Elife. 2016 Jun 9;5. pii: e12213. doi: 10.7554/eLife.12213.

14.

Retroviral DNA Integration.

Lesbats P, Engelman AN, Cherepanov P.

Chem Rev. 2016 Oct 26;116(20):12730-12757. doi: 10.1021/acs.chemrev.6b00125. Epub 2016 May 20. Review.

15.

What Integration Sites Tell Us about HIV Persistence.

Hughes SH, Coffin JM.

Cell Host Microbe. 2016 May 11;19(5):588-98. doi: 10.1016/j.chom.2016.04.010. Review.

16.

Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites.

Serrao E, Cherepanov P, Engelman AN.

J Vis Exp. 2016 Mar 22;(109). doi: 10.3791/53840.

17.

Comparative Analysis of HIV-1 and Murine Leukemia Virus Three-Dimensional Nuclear Distributions.

Quercioli V, Di Primio C, Casini A, Mulder LCF, Vranckx LS, Borrenberghs D, Gijsbers R, Debyser Z, Cereseto A.

J Virol. 2016 Apr 29;90(10):5205-5209. doi: 10.1128/JVI.03188-15. Print 2016 May 15.

18.

LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.

Basu A, Cajigas-Du Ross CK, Rios-Colon L, Mediavilla-Varela M, Daniels-Wells TR, Leoh LS, Rojas H, Banerjee H, Martinez SR, Acevedo-Martinez S, Casiano CA.

PLoS One. 2016 Jan 15;11(1):e0146549. doi: 10.1371/journal.pone.0146549. eCollection 2016.

19.

LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes.

Singh PK, Plumb MR, Ferris AL, Iben JR, Wu X, Fadel HJ, Luke BT, Esnault C, Poeschla EM, Hughes SH, Kvaratskhelia M, Levin HL.

Genes Dev. 2015 Nov 1;29(21):2287-97. doi: 10.1101/gad.267609.115.

20.

Sites of retroviral DNA integration: From basic research to clinical applications.

Serrao E, Engelman AN.

Crit Rev Biochem Mol Biol. 2016;51(1):26-42. doi: 10.3109/10409238.2015.1102859. Epub 2015 Oct 28. Review.

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