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K13 Propeller Alleles, mdr1 Polymorphism, and Drug Effectiveness at Day 3 after Artemether-Lumefantrine Treatment for Plasmodium falciparum Malaria in Colombia, 2014-2015.

Montenegro M, Neal AT, Posada M, De Las Salas B, Lopera-Mesa TM, Fairhurst RM, Tobon-Castaño A.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01036-17. doi: 10.1128/AAC.01036-17. Print 2017 Dec.


Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death.

Serrán-Aguilera L, Denton H, Rubio-Ruiz B, López-Gutiérrez B, Entrena A, Izquierdo L, Smith TK, Conejo-García A, Hurtado-Guerrero R.

Sci Rep. 2016 Sep 12;6:33189. doi: 10.1038/srep33189.


Stearylamine Liposomal Delivery of Monensin in Combination with Free Artemisinin Eliminates Blood Stages of Plasmodium falciparum in Culture and P. berghei Infection in Murine Malaria.

Rajendran V, Rohra S, Raza M, Hasan GM, Dutt S, Ghosh PC.

Antimicrob Agents Chemother. 2015 Dec 14;60(3):1304-18. doi: 10.1128/AAC.01796-15.


Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.

Chaorattanakawee S, Saunders DL, Sea D, Chanarat N, Yingyuen K, Sundrakes S, Saingam P, Buathong N, Sriwichai S, Chann S, Se Y, Yom Y, Heng TK, Kong N, Kuntawunginn W, Tangthongchaiwiriya K, Jacob C, Takala-Harrison S, Plowe C, Lin JT, Chuor CM, Prom S, Tyner SD, Gosi P, Teja-Isavadharm P, Lon C, Lanteri CA.

Antimicrob Agents Chemother. 2015 Aug;59(8):4631-43. doi: 10.1128/AAC.00366-15. Epub 2015 May 26.


Artemisinin-resistant Plasmodium falciparum parasites exhibit altered patterns of development in infected erythrocytes.

Hott A, Casandra D, Sparks KN, Morton LC, Castanares GG, Rutter A, Kyle DE.

Antimicrob Agents Chemother. 2015;59(6):3156-67. doi: 10.1128/AAC.00197-15. Epub 2015 Mar 16.


Decreasing pfmdr1 copy number suggests that Plasmodium falciparum in Western Cambodia is regaining in vitro susceptibility to mefloquine.

Lim P, Dek D, Try V, Sreng S, Suon S, Fairhurst RM.

Antimicrob Agents Chemother. 2015 May;59(5):2934-7. doi: 10.1128/AAC.05163-14. Epub 2015 Feb 23.


The outcome of a test-treat package versus routine outpatient care for Ghanaian children with fever: a pragmatic randomized control trial.

Ameyaw E, Nguah SB, Ansong D, Page I, Guillerm M, Bates I.

Malar J. 2014 Nov 26;13:461. doi: 10.1186/1475-2875-13-461.


Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine.

Zongo I, Somé FA, Somda SA, Parikh S, Rouamba N, Rosenthal PJ, Tarning J, Lindegardh N, Nosten F, Ouédraogo JB.

PLoS One. 2014 Aug 18;9(8):e103200. doi: 10.1371/journal.pone.0103200. eCollection 2014.


Interaction between rifampicin, amodiaquine and artemether in mice infected with chloroquine resistant Plasmodium berghei.

Badejo JA, Abiodun OO, Akinola O, Happi CT, Sowunmi A, Gbotosho GO.

Malar J. 2014 Aug 5;13:299. doi: 10.1186/1475-2875-13-299.


Ex vivo activity of endoperoxide antimalarials, including artemisone and arterolane, against multidrug-resistant Plasmodium falciparum isolates from Cambodia.

Lanteri CA, Chaorattanakawee S, Lon C, Saunders DL, Rutvisuttinunt W, Yingyuen K, Bathurst I, Ding XC, Tyner SD.

Antimicrob Agents Chemother. 2014 Oct;58(10):5831-40. doi: 10.1128/AAC.02462-14. Epub 2014 Jul 21.


A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum.

Sanchez CP, Liu CH, Mayer S, Nurhasanah A, Cyrklaff M, Mu J, Ferdig MT, Stein WD, Lanzer M.

PLoS Genet. 2014 May 15;10(5):e1004382. doi: 10.1371/journal.pgen.1004382. eCollection 2014 May.


Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria.

Bukirwa H, Unnikrishnan B, Kramer CV, Sinclair D, Nair S, Tharyan P.

Cochrane Database Syst Rev. 2014 Mar 4;(3):CD006404. doi: 10.1002/14651858.CD006404.pub2. Review.


Monitoring antimalarial drug resistance: Applying lessons learned from the past in a fast-moving present.

Sibley CH, Price RN.

Int J Parasitol Drugs Drug Resist. 2012 Apr 20;2:126-33. doi: 10.1016/j.ijpddr.2012.03.004. eCollection 2012 Dec. Review.


Four years' monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border.

Phompradit P, Muhamad P, Wisedpanichkij R, Chaijaroenkul W, Na-Bangchang K.

Malar J. 2014 Jan 15;13:23. doi: 10.1186/1475-2875-13-23.


Therapeutic efficacy of fixed dose artesunate-mefloquine for the treatment of acute, uncomplicated Plasmodium falciparum malaria in Kampong Speu, Cambodia.

Leang R, Ros S, Duong S, Navaratnam V, Lim P, Ariey F, Kiechel JR, Ménard D, Taylor WR.

Malar J. 2013 Sep 23;12:343. doi: 10.1186/1475-2875-12-343.


Factoring quality laboratory diagnosis into the malaria control agenda for sub-Saharan Africa.

Aidoo M.

Am J Trop Med Hyg. 2013 Sep;89(3):403-6. doi: 10.4269/ajtmh.13-0108.


A comprehensive survey of polymorphisms conferring anti-malarial resistance in Plasmodium falciparum across Pakistan.

Khattak AA, Venkatesan M, Jacob CG, Artimovich EM, Nadeem MF, Nighat F, Hombhanje F, Mita T, Malik SA, Plowe CV.

Malar J. 2013 Aug 29;12:300. doi: 10.1186/1475-2875-12-300.


Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers.

Lim P, Dek D, Try V, Eastman RT, Chy S, Sreng S, Suon S, Mao S, Sopha C, Sam B, Ashley EA, Miotto O, Dondorp AM, White NJ, Su XZ, Char MC, Anderson JM, Amaratunga C, Menard D, Fairhurst RM.

Antimicrob Agents Chemother. 2013 Nov;57(11):5277-83. doi: 10.1128/AAC.00687-13. Epub 2013 Aug 12.


The interplay between drug resistance and fitness in malaria parasites.

Rosenthal PJ.

Mol Microbiol. 2013 Sep;89(6):1025-38. doi: 10.1111/mmi.12349. Epub 2013 Aug 16. Review.


A novel flow cytometric hemozoin detection assay for real-time sensitivity testing of Plasmodium falciparum.

Rebelo M, Sousa C, Shapiro HM, Mota MM, Grobusch MP, Hänscheid T.

PLoS One. 2013 Apr 24;8(4):e61606. doi: 10.1371/journal.pone.0061606. Print 2013.

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